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Abstract

MR anatomy of the substantia innominata and findings in Alzheimer disease: a preliminary report.

M Sasaki, S Ehara, Y Tamakawa, S Takahashi, H Tohgi, A Sakai and T Mita
American Journal of Neuroradiology November 1995, 16 (10) 2001-2007;
M Sasaki
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S Ehara
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Y Tamakawa
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S Takahashi
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H Tohgi
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A Sakai
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T Mita
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Abstract

PURPOSE To demonstrate normal MR anatomy of the substantia innominata and its changes in Alzheimer disease on MR imaging.

METHODS Using a 1.5-T superconductive MR unit, thickness of the substantia innominata was measured on coronal thin-section images obtained in 22 patients with Alzheimer disease and 14 age-matched control subjects. Comparison of these images with postmortem specimens of human brain was also performed.

RESULTS On T2-weighted images through the anterior commissure, the substantia innominata was clearly identified between the globus pallidus and the anterior perforated substance. In Alzheimer disease, thinning of the substantia innominata was more frequently observed than in the age-matched controls.

CONCLUSION Thin-section T2-weighted coronal MR images can demonstrate shrinkage of the substantia innominata, a finding that may aid in the diagnosis of Alzheimer disease.

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American Journal of Neuroradiology
Vol. 16, Issue 10
1 Nov 1995
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MR anatomy of the substantia innominata and findings in Alzheimer disease: a preliminary report.
M Sasaki, S Ehara, Y Tamakawa, S Takahashi, H Tohgi, A Sakai, T Mita
American Journal of Neuroradiology Nov 1995, 16 (10) 2001-2007;

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MR anatomy of the substantia innominata and findings in Alzheimer disease: a preliminary report.
M Sasaki, S Ehara, Y Tamakawa, S Takahashi, H Tohgi, A Sakai, T Mita
American Journal of Neuroradiology Nov 1995, 16 (10) 2001-2007;
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Cited By...

  • Assessment of the Virchow-Robin Spaces in Alzheimer Disease, Mild Cognitive Impairment, and Normal Aging, Using High-Field MR Imaging
  • Atrophy Measurement of the Anterior Commissure and Substantia Innominata with 3T High-Resolution MR Imaging: Does the Measurement Differ for Patients with Frontotemporal Lobar Degeneration and Alzheimer Disease and for Healthy Subjects?
  • MR Analysis of the Substantia Innominata in Normal Aging, Alzheimer Disease, and Other Types of Dementia
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