Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
    • COVID-19 Content and Resources
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in
  • Log out

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in
  • Log out

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
    • COVID-19 Content and Resources
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Abstract

MR in temporal lobe epilepsy: analysis with pathologic confirmation.

D H Lee, F Q Gao, J M Rogers, I Gulka, I R Mackenzie, A G Parrent, C S Kubu, D G Munoz, R S McLachlan, W T Blume and J P Girvin
American Journal of Neuroradiology January 1998, 19 (1) 19-27;
D H Lee
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F Q Gao
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J M Rogers
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
I Gulka
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
I R Mackenzie
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A G Parrent
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C S Kubu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D G Munoz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R S McLachlan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W T Blume
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J P Girvin
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

PURPOSE We evaluated the MR findings in patients with temporal lobe epilepsy to determine the predictive value of MR imaging in assessing patient outcome.

METHODS MR studies from 186 of 274 consecutive patients who underwent temporal lobectomy for intractable epilepsy were reviewed retrospectively. Images were interpreted by an experienced neuroradiologist, who was blinded to the side of seizure activity and to pathologic findings.

RESULTS MR imaging exhibited 93% sensitivity and 83% specificity in detecting hippocampal/amygdalar abnormalities (n = 121), and 97% sensitivity and 97% specificity in detecting abnormalities in the rest of the temporal lobe (n = 60). Abnormal high signal of the hippocampus on T2-weighted images had a sensitivity of 93% and specificity of 74% in predicting mesial temporal sclerosis (n = 115). The presence of hippocampal atrophy on MR correlated with the duration of seizures. Sensitivity and specificity of MR imaging in detecting temporal lobe tumors (n = 42) were 83% and 97%, respectively, based on abnormal signal and mass effect. After surgery, 63% of patients were seizure free and 28% had a significant reduction of seizure frequency at an average of 24 months (range, 12 to 78 months) after surgery. Patients with a single lesion in the anterior temporal lobe or hippocampus/amygdala had a better outcome than patients with multiple lesions (n = 22). Interrater agreement varied from 0.4 to 0.93, with best agreement for tumors or abnormal hippocampal signal on T2-weighted images.

CONCLUSION MR imaging is highly sensitive in detecting and locating abnormalities in the temporal lobe and the hippocampus/amygdala in patients with temporal lobe epilepsy. Hippocampal atrophy appears to correspond to the duration of seizure disorder.

  • Copyright © American Society of Neuroradiology
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology
Vol. 19, Issue 1
1 Jan 1998
  • Table of Contents
  • Index by author
Advertisement
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
MR in temporal lobe epilepsy: analysis with pathologic confirmation.
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
MR in temporal lobe epilepsy: analysis with pathologic confirmation.
D H Lee, F Q Gao, J M Rogers, I Gulka, I R Mackenzie, A G Parrent, C S Kubu, D G Munoz, R S McLachlan, W T Blume, J P Girvin
American Journal of Neuroradiology Jan 1998, 19 (1) 19-27;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
MR in temporal lobe epilepsy: analysis with pathologic confirmation.
D H Lee, F Q Gao, J M Rogers, I Gulka, I R Mackenzie, A G Parrent, C S Kubu, D G Munoz, R S McLachlan, W T Blume, J P Girvin
American Journal of Neuroradiology Jan 1998, 19 (1) 19-27;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Voxel-Based Morphometry--from Hype to Hope. A Study on Hippocampal Atrophy in Mesial Temporal Lobe Epilepsy
  • Seizure outcome after epilepsy surgery in patients with normal preoperative MRI
  • Paroxysmal hypertension during a complex partial seizure
  • Quantitative magnetic resonance characterization of mesial temporal sclerosis in childhood
  • BRAIN IMAGING
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

Similar Articles

Advertisement

News and Updates

  • Lucien Levy Best Research Article Award
  • Thanks to our 2022 Distinguished Reviewers
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2023 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire