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Abstract

Sagittal MR of multiple sclerosis in the spinal cord: fast versus conventional spin-echo imaging.

G J Lycklama à Nijeholt, J A Castelijns, J Weerts, H Adèr, J H van Waesberghe, C Polman and F Barkhof
American Journal of Neuroradiology February 1998, 19 (2) 355-360;
G J Lycklama à Nijeholt
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J A Castelijns
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J Weerts
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H Adèr
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J H van Waesberghe
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C Polman
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F Barkhof
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Abstract

PURPOSE We compared conventional spin-echo (CSE) with fast spin-echo (FSE) dual-echo MR images to determine which of these sequences was better able to depict spinal cord abnormalities in patients with multiple sclerosis (MS).

METHODS CSE and FSE dual-echo MR images were obtained in 37 patients with MS and in six healthy control subjects, all of whom were examined on a 1.0-T MR unit with a phased-array coil and cardiac triggering. Two blinded interpreters graded the MR studies, first separately and then by consensus. Images were scored for presence of artifacts, number of focal lesions, and presence of a diffuse increase in signal intensity.

RESULTS No abnormalities were seen in the volunteers. The CSE sequences were significantly less hindered by MR imaging artifacts than were the FSE sequences. Interobserver agreement was slightly higher for the CSE than the FSE sequences. After reaching a consensus, the observers found that both CSE and FSE techniques enabled detection of approximately the same number of focal lesions; however, in three patients, small single lesions seen on the CSE images were missed on the FSE images. Also, depiction of a diffuse increase in signal intensity was better on the CSE images. As a result, more patients had abnormal findings on the CSE sequences than on the FSE sequences (35 versus 31).

CONCLUSION Cardiac-triggered dual-echo FSE sequences are almost as good as CSE sequences for depicting spinal MS lesions. Therefore, in cases of established spinal MS, FSE techniques may be as effective as CSE techniques. Because sensitivity for subtle abnormalities is lower with FSE imaging, CSE remains the preferred technique for patients with suspected MS of the spinal cord.

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American Journal of Neuroradiology
Vol. 19, Issue 2
1 Feb 1998
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Sagittal MR of multiple sclerosis in the spinal cord: fast versus conventional spin-echo imaging.
G J Lycklama à Nijeholt, J A Castelijns, J Weerts, H Adèr, J H van Waesberghe, C Polman, F Barkhof
American Journal of Neuroradiology Feb 1998, 19 (2) 355-360;

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Sagittal MR of multiple sclerosis in the spinal cord: fast versus conventional spin-echo imaging.
G J Lycklama à Nijeholt, J A Castelijns, J Weerts, H Adèr, J H van Waesberghe, C Polman, F Barkhof
American Journal of Neuroradiology Feb 1998, 19 (2) 355-360;
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Cited By...

  • Spinal cord abnormalities in recently diagnosed MS patients: Added value of spinal MRI examination
  • Magnetization-Transfer Histogram Analysis of the Cervical Cord in Patients with Multiple Sclerosis
  • Comparison of Three MR Sequences for the Detection of Cervical Cord Lesions in Patients with Multiple Sclerosis
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