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Research ArticlePEDIATRICS

Reproducibility and Accuracy of MR Imaging of the Brain after Severe Birth Asphyxia

Phillipe Jouvet, Francis M. Cowan, Philip Cox, Edward Lazda, Mary A. Rutherford, Jonathan Wigglesworth, Huseyin Mehmet and A. David Edwards
American Journal of Neuroradiology July 1999, 20 (7) 1343-1348;
Phillipe Jouvet
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Francis M. Cowan
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Philip Cox
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Edward Lazda
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Mary A. Rutherford
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Jonathan Wigglesworth
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Huseyin Mehmet
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A. David Edwards
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    fig 1.

    MR images.

    A, Normal control participant, aged 2 days. Inversion recovery sequence (3800/30; inversion time, 950) shows normal appearances with high signal intensity, consistent with myelin within the posterior half of the posterior limb of the internal capsule.

    B, Neonate with severe birth asphyxia, aged 2 days. No high signal from myelin in the posterior limb of the internal capsule occurs.

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    fig 2.

    Histologic findings of the posterior limb of the internal capsule sections stained with hematoxylin and eosin (original magnification, ×300).

    A, Normal histologic findings of the posterior limb of the internal capsule.

    B, Abnormal histologic findings of the posterior limb of the internal capsule show marked interstitial edema and nuclear pyknosis of many of the glial cells.

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    TABLE 1:

    Characteristics of the newborns included in the accuracy and reproducibility study of early MR brain imaging

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    TABLE 2:

    MR imaging criteria used to compare early MR imaging and pathology findings in 8 infants with severe hypoxic-ischaemic encephalopathy

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    TABLE 3:

    Interobserver variation in imaging interpretation

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    TABLE 4:

    Accuracy of MR imaging for prediction of neuropathological findings after birth asphyxia

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American Journal of Neuroradiology
Vol. 20, Issue 7
1 Jul 1999
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Reproducibility and Accuracy of MR Imaging of the Brain after Severe Birth Asphyxia
Phillipe Jouvet, Francis M. Cowan, Philip Cox, Edward Lazda, Mary A. Rutherford, Jonathan Wigglesworth, Huseyin Mehmet, A. David Edwards
American Journal of Neuroradiology Jul 1999, 20 (7) 1343-1348;

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Reproducibility and Accuracy of MR Imaging of the Brain after Severe Birth Asphyxia
Phillipe Jouvet, Francis M. Cowan, Philip Cox, Edward Lazda, Mary A. Rutherford, Jonathan Wigglesworth, Huseyin Mehmet, A. David Edwards
American Journal of Neuroradiology Jul 1999, 20 (7) 1343-1348;
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Cited By...

  • Antemortem cranial MRI compared with postmortem histopathologic examination of the brain in term infants with neonatal encephalopathy following perinatal asphyxia
  • Prognostic Tests in Term Neonates With Hypoxic-Ischemic Encephalopathy: A Systematic Review
  • Comparative Prognostic Utilities of Early Quantitative Magnetic Resonance Imaging Spin-Spin Relaxometry and Proton Magnetic Resonance Spectroscopy in Neonatal Encephalopathy
  • Diffusion-Weighted Magnetic Resonance Imaging in Term Perinatal Brain Injury: A Comparison With Site of Lesion and Time From Birth
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More in this TOC Section

  • Thalamus L-Sign: A Potential Biomarker of Neonatal Partial, Prolonged Hypoxic-Ischemic Brain Injury or Hypoglycemic Encephalopathy?
  • Stroke Recurrence in Children with Vertebral Artery Dissecting Aneurysm
  • An In-Depth Analysis of Brain and Spine Neuroimaging in Children with Abusive Head Trauma: Beyond the Classic Imaging Findings
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