Visualization of Intravenously Administered Contrast Material in the CSF on Fluid-AttenuatedInversion-Recovery MR Images: An In Vitro and Animal-Model Investigation

fig. 2. A and B, Noncontrast FLAIR image (A) shows the expected dark cortical sulci over the frontal convexity. Contrast-enhanced FLAIR image (B) 15 minutes after injection of a triple dose of contrast material shows high signal in multiple sulci, most consistent with contrast effects

fig. 3. A and B, Sagittal FLAIR image (A) (10,007/189, TI = 2200; 5-mm-thick sections) in dog 2 immediately after injection of contrast agent (0.1 mmol/kg) reveals the expected low signal intensity of CSF in the fourth ventricle (arrow). Sagittal FLAIR image 30 minutes after contrast administration (B) shows that the CSF in the fourth ventricle is now isointense with surrounding brain (arrow)

fig. 4. A–C, Sagittal T1-weighted image (A) (550/15/1) obtained 6 hours after IV contrast administration (0.3 mmol/kg) shows the expected low-signal CSF in the cingulate sulcus (arrow). Sagittal FLAIR image (B), also obtained 6 hours after triple-dose contrast injection, shows abnormal high signal in the premedullary cistern (black arrow) as well as the cingulate sulcus (white arrow). The abnormal CSF signal on the coronal FLAIR image (C) is striking in the occipital sulci (arrows)

fig. 5. A and B, Images of the phantom obtained with FLAIR (10,000/154, TI = 1630) (A) and T1-weighted (400/16/1) (B) techniques. The lower tubes contain increasing dilutions of gadodiamide. There are more bright tubes in the lower two rows (lowest concentrations of contrast material) on the FLAIR image than on the T1-weighted image.