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Research ArticleBRAIN

Magnetization Transfer Ratio Histogram Analysis of Gray Matter in Relapsing-remitting Multiple Sclerosis

Yulin Ge, Robert I. Grossman, Jayaram K. Udupa, James S. Babb, Dennis L. Kolson and Joseph C. McGowan
American Journal of Neuroradiology March 2001, 22 (3) 470-475;
Yulin Ge
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Robert I. Grossman
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Jayaram K. Udupa
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James S. Babb
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Dennis L. Kolson
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Joseph C. McGowan
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References

  1. ↵
    Grossman RI, Gomori JM, Ramer KN, et al. Magnetization transfer: theory and clinical applications in neuroradiology. Radiographics 1994;14:279-290
    PubMedWeb of Science
  2. van Buchem MA, Grossman RI, Armstrong C, et al. Correlation of volumetric magnetization transfer imaging with clinical data in multiple sclerosis. Neurology 1998;50:1609-1617
    Abstract/FREE Full Text
  3. ↵
    Grossman RI, McGowan JC. Perspective of multiple sclerosis. AJNR Am J Neuroradiol 1998;19:1251-1265
    PubMedWeb of Science
  4. ↵
    Wolff SD, Balaban RS. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med 1989;10:135-144
    CrossRefPubMedWeb of Science
  5. ↵
    Dousset V, Grossman RI, Ramer KN, et al. Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology 1992;182:483-491
    PubMedWeb of Science
  6. ↵
    van Buchem MA, McGowan JC, Kolson DL, Polansky M, Grossman RI. Quantitative volumetric magnetization transfer analysis in multiple sclerosis: estimation of macroscopic and microscopic disease burden. Magn Reson Med 1996;36:632-636
    PubMedWeb of Science
  7. Dousset V, Gayou A, Brochet B, Caille JM. Early structural changes in acute nascent MS lesions suggesting demyelination and remyelination assessed by in vivo serial quantitative magnetization transfer studies. Neurology 1998;51:1150-1155
    Abstract/FREE Full Text
  8. Lexa FJ, Grossman RI, Rosenquist AC. MR of wallerian degeneration in the feline visual system: characterization by magnetization transfer rate with histopathologic correlation. AJNR Am J Neuroradiol 1994;15:201-212
    Abstract/FREE Full Text
  9. ↵
    Kasner SE, Galetta SL, McGowan JC, Grossman RI. Magnetization transfer imaging in progressive multifocal leukoencephalopathy. Neurology 1997;48:534-536
    Abstract/FREE Full Text
  10. McGowan JC, McCormack TM, Grossman RI, et al. Diffuse axonal pathology detected with magnetization transfer imaging following brain injury in the pig. Magn Reson Med 1999;41:727-733
    CrossRefPubMedWeb of Science
  11. ↵
    Gass A, Barker GJ, Kidd D, Thorpe JW, et al. Correlation of magnetization transfer ratio with clinical disability in multiple sclerosis. Ann Neurol 1994;36:62-67
    CrossRefPubMedWeb of Science
  12. ↵
    Loevner LA, Grossman RI, Cohen JA, et al. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196:511-515
    PubMedWeb of Science
  13. Catalaa I, Grossman RI, Kolson DL, et al. Magnetization transfer histogram analysis of segmented normal-appearing white matter in multiple sclerosis. Radiology 2000;26:351-355
  14. ↵
    van Buchem MA, Udupa JK, Heyning FH, et al. Global volumetric estimation of disease burden in multiple sclerosis based on magnetization transfer imaging. AJNR Am J Neuroradiol 1997;18:1287-1290
    Abstract
  15. Philips MD, Grossman RI, Miki Y, et al. Comparison of T2 lesion volume on magnetization transfer ratio histogram analysis and of lesion burden in patients with multiple sclerosis. AJNR Am J Neuroradiol 1998;19:1055-1060
    Abstract
  16. ↵
    Miki Y, Grossman RI, Udupa JK, et al. Differences between relapsing-remitting and chronic progressive multiple sclerosis as determined with quantitative MR imaging. Radiology 1999;210:769-774
    PubMedWeb of Science
  17. ↵
    Brownell B, Hughes JT. The distribution of plaques in the cerebrum in multiple sclerosis. J Neurol Neurosurg Psychiatry 1962;25:315-320
  18. Ikuta F, Zimmerman HM. Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States. Neurology 1976;26:26-28
    FREE Full Text
  19. ↵
    Newcombe J, Hawkins CP, Henderson CL, et al. Histopathology of multiple sclerosis lesions detected by magnetic resonance imaging in unfixed postmortem central nervous system tissue. Brain 1991;114:1013-1023
    Abstract/FREE Full Text
  20. Catalaa I, Fulton JC, Zhang X, et al. MR imaging quantitation of gray matter involvement in multiple sclerosis and its correlation with disability measures and neurocognitive testing. AJNR Am J Neuroradiol 1999;20:1613-1618
    Abstract/FREE Full Text
  21. ↵
    Trapp BD, Peterson J, Ransohoff RM, Rudick R, Mork S, Bo L. Axonal transaction in the lesions of multiple sclerosis. New Engl J Med 1998;85:278-285
  22. ↵
    McAlpine D. Symptoms and signs. In: McAlpine D, Lumsden CE, Acheson ED. Multiple Sclerosis: A Reappraisal. 2nd ed. Edinburgh: Churchill Livingstone 1972:174-177
  23. ↵
    Kahana E, Leibowitz U, Alter M. Cerebral multiple sclerosis. Neurology 1971;21:1179-1185
    FREE Full Text
  24. ↵
    Matthews WB. Epilepsy and disseminated sclerosis. Quart J Med 1962;31:141-155
    FREE Full Text
  25. ↵
    Rao SM, Leo GJ, Haughton VM, St. Aubin-Faubert P, Bernardin L. Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis. Neurology 1989;39:161-166
    Abstract/FREE Full Text
  26. ↵
    Poser S. Multiple Sclerosis: an Analysis of 812 Cases by Means of Electronic Data Processing.. Berlin: Springer 1978;
  27. ↵
    Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-1452
    Abstract/FREE Full Text
  28. ↵
    McGowan JC, Schnall MD, Leigh JS. Magnetization transfer imaging with pulsed off-resonance saturation: variation in contrast with saturation duty cycle. JMRI 1994;4:79-82
  29. ↵
    Udupa JK, Odhner D, Samarasekera S, et al. 3DVIEWNIX: an open, transportable, multidimensional, multimodality, multiparametric imaging software system. SPIE Proc 1994;2164:58-73
    CrossRef
  30. ↵
    Udupa JK, Samarasekera S. Fuzzy connectedness and object definition: theory, algorithms and applications in imaging segmentation. Graph Models Image Proc 1996;33:480-489
  31. Udupa JK, Wei L, Samasekera S, Miki Y, van Buchem MA, Grossman RI. Multiple sclerosis lesion quantification using fuzzy connectedness principles. IEEE Trans Med Imaging 1997;16:598-609
    CrossRefPubMedWeb of Science
  32. ↵
    Schmidt RE. Demyelinating disease. In: Nelson JS, Parisi JE, Schochet SS, eds. Principles and Practice of Neuropathology. St Louis: Mosby 1993;369-379
  33. ↵
    Zimmerman HM, Netskey MG. The pathology of multiple sclerosis. Res Publ Assoc Nerv Ment Dis 1950;28:271-312
  34. Ge Y, Grossman RI, Udupa JK, et al. Longitudinal quantitative analysis of brain atrophy in relapsing-remitting and secondary-progressive multiple sclerosis. Radiology 2000;214:665-670
    PubMedWeb of Science
  35. ↵
    Grossman RI, Lenkinski RE, Ramer KN, et al. MR proton spectroscopy in multiple sclerosis. AJNR Am J Neuroradiol 1992;13:1535-1543
    Abstract/FREE Full Text
  36. Matthews PM, Pioro E, Narayanan S, et al. Assessment of lesion pathology in multiple sclerosis using quantitative MRI morphometry and magnetic resonance spectroscopy. Brain 1996;119:715-722
    Abstract/FREE Full Text
  37. ↵
    DeStefano N, Matthews P, Antel J, et al. Chemical pathology of acute demyelination lesions and its correlation with disability. Ann Neurol 1995;38:901-909
    CrossRefPubMedWeb of Science
  38. Arnord DL, Riess GT, Matthews PM, et al. Use of proton magnetic resonance spectroscopy for monitoring disease progression in multiple sclerosis. Ann Neurol 1994;36:76-82
    CrossRefPubMedWeb of Science
  39. Hiehle JF, Lenkinski RE, Grossman RI, et al. Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis. Magn Reson Med 1994;32:285-293
    PubMedWeb of Science
  40. ↵
    Gonen O, Catalaa I, Babb JS, et al. Total brain N-acetylaspartate concentration decline with age in relapsing-remitting multiple sclerosis. Neurology 2000;54:15-19
    Abstract/FREE Full Text
  41. ↵
    Losseff NA, Wang L, Lai HM, et al. Progressive cerebral atrophy in multiple sclerosis: a serial MRI study. Brain 1996;199:2009-2019
  42. ↵
    Mammi S, Filippi M, Martinelli V, et al. Correlation between brain MRI lesion volume and disability in patients with multiple sclerosis. Acta Neurol Scand 1996;94:93-96
    PubMed
  43. ↵
    Losseff NA, Webb SL, O'Riordan JI, et al. Spinal cord atrophy and disability in multiple sclerosis: a new reproducible and sensitive MRI method with potential to monitor disease progression. Brain 1996;119:701-708
    Abstract/FREE Full Text
  44. ↵
    Blinkenberg M, Jensen CV, Holm S, et al. A longitudinal study of cerebral glucose metabolism, MRI, and disability in patients with MS. Neurology 1999;53:149-153
    Abstract/FREE Full Text
  45. Yamada K, Patel U, Shrier DA, Tanaka H, Chang JK, Numaguchi Y. MR imaging of CNS tractopathy: wallerian and transneuronal degeneration. AJR Am J Roentgenol 1998;171:813-818
    PubMed
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American Journal of Neuroradiology
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Magnetization Transfer Ratio Histogram Analysis of Gray Matter in Relapsing-remitting Multiple Sclerosis
Yulin Ge, Robert I. Grossman, Jayaram K. Udupa, James S. Babb, Dennis L. Kolson, Joseph C. McGowan
American Journal of Neuroradiology Mar 2001, 22 (3) 470-475;

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Magnetization Transfer Ratio Histogram Analysis of Gray Matter in Relapsing-remitting Multiple Sclerosis
Yulin Ge, Robert I. Grossman, Jayaram K. Udupa, James S. Babb, Dennis L. Kolson, Joseph C. McGowan
American Journal of Neuroradiology Mar 2001, 22 (3) 470-475;
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