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Research ArticleBRAIN

Multivoxel 3D Proton Spectroscopy in the Brain at 1.5 Versus 3.0 T: Signal-to-Noise Ratio and Resolution Comparison

Oded Gonen, Stephan Gruber, Belinda S. Y. Li, Vladimir Mlynárik and Ewald Moser
American Journal of Neuroradiology October 2001, 22 (9) 1727-1731;
Oded Gonen
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Stephan Gruber
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Belinda S. Y. Li
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Vladimir Mlynárik
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Ewald Moser
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    fig 1.

    Schematic of the hybrid HSI-CSI localization sequence. A 25.6- or 15-ms, 60- or 120-Hz water suppression at 1.5 or 3.0 T was followed by VOI excitation. The PRESS 5.12-ms 90° pulse also performed fourth-order HSI (HSI) along ZIS with 3 or 4.5 mT/m gradients at 1.5 or 3.0 T, respectively, followed 26.07 and 98.69 ms later by 10.24 ms SLR 180° pulses with 1 mT/m. Localization along XLR and YAP was 16 × 16 2D CSI. A 25.6- or 15-ms gaussian 180° BASING pulse was applied between the two SLR pulses for extra water suppression

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    fig 2.

    Corresponding (within 2–3 mm IS) axial T1-weighted MR images from the section richest in anatomic features from the same subject. Both are superimposed with the outline of the 9 × 9-cm VOIs and the real part of the corresponding 9 × 9 1H-spectra matrices. The horizontal (1.8–3.5-ppm) scale is common to both fields.

    A, Examination at 1.5 T.

    B, Examination at 3.0 T.

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    fig 3.

    Five spectra from the corresponding dashed boxes in figure 2 scaled to the same maximum NAA peak height. Note an improved Cr-Cho spectral resolution, better SNR, and flatter baseline between 2 and 3 ppm at 3.0 versus 1.5 T

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  • Table1

    Average voxel linewidths and SNRs from approximately 900 voxels

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American Journal of Neuroradiology: 22 (9)
American Journal of Neuroradiology
Vol. 22, Issue 9
1 Oct 2001
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Multivoxel 3D Proton Spectroscopy in the Brain at 1.5 Versus 3.0 T: Signal-to-Noise Ratio and Resolution Comparison
Oded Gonen, Stephan Gruber, Belinda S. Y. Li, Vladimir Mlynárik, Ewald Moser
American Journal of Neuroradiology Oct 2001, 22 (9) 1727-1731;

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Multivoxel 3D Proton Spectroscopy in the Brain at 1.5 Versus 3.0 T: Signal-to-Noise Ratio and Resolution Comparison
Oded Gonen, Stephan Gruber, Belinda S. Y. Li, Vladimir Mlynárik, Ewald Moser
American Journal of Neuroradiology Oct 2001, 22 (9) 1727-1731;
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