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Research ArticleBRAIN

Angiotropic Large Cell Lymphoma with Imaging Characteristics of CNS Vasculitis

Debbie K. Song, Nicholas M. Boulis, Paul E. McKeever and Douglas J. Quint
American Journal of Neuroradiology February 2002, 23 (2) 239-242;
Debbie K. Song
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Nicholas M. Boulis
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Paul E. McKeever
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Douglas J. Quint
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Fig 4.

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Fig 4.

Histologic specimens confirming ALCL.

A, Immunostaining with L26, a monoclonal antibody B cell marker, reveals large, atypical intravascular tumor cells occluding the lumen of a small cerebral blood vessel. Note the large ratio of vessel diameter to wall thickness, indicative of neoplastic lymphocytes occluding and distending the vessel lumen. In contrast to a true vasculitic process, the vessel wall itself does not show inflammatory damage.

B, Hematoxylin and eosin staining shows gray (black arrow) and white (white arrows) matter infarctions resulting from blood flow compromised by intravascular lymphoma.

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American Journal of Neuroradiology: 42 (2)
American Journal of Neuroradiology
Vol. 42, Issue 2
1 Feb 2021
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Angiotropic Large Cell Lymphoma with Imaging Characteristics of CNS Vasculitis
Debbie K. Song, Nicholas M. Boulis, Paul E. McKeever, Douglas J. Quint
American Journal of Neuroradiology Feb 2002, 23 (2) 239-242;

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Angiotropic Large Cell Lymphoma with Imaging Characteristics of CNS Vasculitis
Debbie K. Song, Nicholas M. Boulis, Paul E. McKeever, Douglas J. Quint
American Journal of Neuroradiology Feb 2002, 23 (2) 239-242;
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  • Intravascular Lymphoma: The Oncologist's "Great Imitator".
  • Paraplegia and Sensory Deficit Caused by Angiotropic Large Cell Lymphoma
  • A Case of Intravascular Lymphoma with Increased Regional Cerebral Blood Flow in I-123 IMP Single-Photon Emission CT
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