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Histopathologic Findings in Human Cerebral Aneurysms Embolized with Platinum Coils: Report of Two Cases and Review of the Literature
Shoichiro Ishihara, Michel E. Mawad, Kentaro Ogata, Chihiro Suzuki, Nobusuke Tsuzuki, Hiroshi Katoh, Akira Ohnuki, Takahito Miyazawa, Hiroshi Nawashiro, Tatsumi Kaji and Katsuji Shima
American Journal of Neuroradiology June 2002, 23 (6) 970-974;
Shoichiro Ishihara
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
Michel E. Mawad
eDepartment of Neuroradiology, The Methodist Hospital, Baylor College of Medicine, Houston, TX
Kentaro Ogata
cDepartment of Pathology, National Defense Medical College, Tokorozawa, Japan
Chihiro Suzuki
dDepartment of Neurosurgery, Musashino General Hospital, Kawagoe, Japan
Nobusuke Tsuzuki
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
Hiroshi Katoh
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
Akira Ohnuki
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
Takahito Miyazawa
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
Hiroshi Nawashiro
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
Tatsumi Kaji
bDepartment of Radiology, National Defense Medical College, Tokorozawa, Japan
Katsuji Shima
aDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Japan

Abstract
Summary: This report describes 2-week and 20-month histopathologic findings in small aneurysms embolized with platinum coils. Electron microscopy showed the presence of endothelial cells encroaching on the platinum coils at the orifice of the aneurysm in both cases. We confirm that endothelial growth can be induced as early as 2 weeks after embolization of small human aneurysms with platinum coils, similar to previous observations in animal models and human cases.
- Copyright © American Society of Neuroradiology
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Histopathologic Findings in Human Cerebral Aneurysms Embolized with Platinum Coils: Report of Two Cases and Review of the Literature
Shoichiro Ishihara, Michel E. Mawad, Kentaro Ogata, Chihiro Suzuki, Nobusuke Tsuzuki, Hiroshi Katoh, Akira Ohnuki, Takahito Miyazawa, Hiroshi Nawashiro, Tatsumi Kaji, Katsuji Shima
American Journal of Neuroradiology Jun 2002, 23 (6) 970-974;
Histopathologic Findings in Human Cerebral Aneurysms Embolized with Platinum Coils: Report of Two Cases and Review of the Literature
Shoichiro Ishihara, Michel E. Mawad, Kentaro Ogata, Chihiro Suzuki, Nobusuke Tsuzuki, Hiroshi Katoh, Akira Ohnuki, Takahito Miyazawa, Hiroshi Nawashiro, Tatsumi Kaji, Katsuji Shima
American Journal of Neuroradiology Jun 2002, 23 (6) 970-974;
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