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Research ArticleBRAIN

Contrast-Enhanced 2D Cine Phase MR Angiography for Measurement of Basilar Artery Blood Flow in Posterior Circulation Ischemia

Takeshi Kato, Toshikatsu Indo, Eiji Yoshida, Yasushi Iwasaki, Mie Sone and Gen Sobue
American Journal of Neuroradiology September 2002, 23 (8) 1346-1351;
Takeshi Kato
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Toshikatsu Indo
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Eiji Yoshida
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Yasushi Iwasaki
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Mie Sone
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Gen Sobue
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    Fig 1.

    Gradient recalled acquisition in the steady state and contrast-enhanced 2D cine phase MR images.

    A, For the determination of the transverse image plane, a sagittal gradient recalled acquisition in the steady state MR image (20/5; flip angle, 60 degrees) was created. The imaging plane was determined at the midpontine level to be perpendicular to the basilar artery.

    B, Contrast-enhanced 2D cine phase MR image (40/11.8; flip angle, 30 degrees), acquired at 32 phase. Note the basilar artery as an area of hypointensity (arrow).

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    Fig 2.

    3D time-of-flight MR angiograms and blood flow velocity data plots.

    A, 3D time-of-flight MR angiogram (33/4; flip angle, 20 degrees) of a 49-year-old male patient with PCI and dizziness shows narrowing of the right vertebral and basilar arteries. Change of blood flow velocity between systolic and diastolic phases was greater in the patient than in the normal control volunteer (see B).

    B, 3D time-of-flight MR angiogram (33/4; flip angle, 20 degrees) of a 54-year-old female control participant with no clinical signs or symptoms shows mild meandering of the basilar artery.

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    TABLE 1:

    Clinical backgrounds, symptoms, and risk factors in posterior circulation ischemia and control groups

    PCI GroupControl GroupP
    Clinical Backgrounds
    N (male vs female)21 (10:11)16 (11:5)NS†
    Age range, y (mean)41–80 (61.3)40–85 (61.6)NS*
    Body mass index,kg/m224.8 ± 4.022.7 ± 3.9NS*
    SBP, mm Hg
     Intermittent135.0 ± 18.1NS*
     Attack148.6 ± 19.6132.3 ± 12.9<.001
    Clinical Symptoms
    Paroxysmal vertigo (with nystagmus)5 (3)0
    Paroxysmal dizziness (with nystagmus)16 (1)0
    Hearing loss22
    Headache01
    Chronic neurologic deficit03
    Transient neurologic deficit40
    Risk Factors for Cerebral Blood Flow
    Hypertension113NS†
    Diabetes Mellitus10NS†
    Hyperlipidemia77NS†
    Smoking34NS†
    • Note.—PCB, posterior circulation ischemia; SBP, systolic blood pressure; hypertension, SBP > 140 mm Hg; diabetes mellitus, fasting blood glucose level > 200 mg/dL; hyperlipidemia, total blood cholesterol level > 200 mg/dL or neutral fat > 160 mg/dL; smoker, habitual smoking during study.

    • * Student t test.

    • † Fisher exact probability test.

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    TABLE 2:

    Average flow velocity and flow volume rate of the basilar artery in posterior circulation ischemia and control groups

    PCI GroupControl GroupP*
    Range of interest, cm20.10 ± 0.030.11 ± 0.03NS
    Maximum average velocity, cm/s29.2 ± 9.238.5 ± 8.2<.005
    Minimum average velocity, cm/s10.0 ± 4.011.3 ± 5.0NS
    Mean average velocity, cm/s18.0 ± 5.622.6 ± 5.0<.01
    Flow volume rate, mL/min103.3 ± 37.3148.8 ± 40.0<.001
    • Note.—PCI indicates posterior cerebral ischemia.

    • * Student t test.

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American Journal of Neuroradiology: 23 (8)
American Journal of Neuroradiology
Vol. 23, Issue 8
1 Sep 2002
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Contrast-Enhanced 2D Cine Phase MR Angiography for Measurement of Basilar Artery Blood Flow in Posterior Circulation Ischemia
Takeshi Kato, Toshikatsu Indo, Eiji Yoshida, Yasushi Iwasaki, Mie Sone, Gen Sobue
American Journal of Neuroradiology Sep 2002, 23 (8) 1346-1351;

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Contrast-Enhanced 2D Cine Phase MR Angiography for Measurement of Basilar Artery Blood Flow in Posterior Circulation Ischemia
Takeshi Kato, Toshikatsu Indo, Eiji Yoshida, Yasushi Iwasaki, Mie Sone, Gen Sobue
American Journal of Neuroradiology Sep 2002, 23 (8) 1346-1351;
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