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Research ArticleINTERVENTIONAL

Stent-Assisted Angioplasty of Intracranial Vertebrobasilar Atherosclerosis: Midterm Analysis of Clinical and Radiologic Predictors of Neurological Morbidity and Mortality

Michael M. Chow, Thomas J. Masaryk, Henry H. Woo, Marc R. Mayberg and Peter A. Rasmussen
American Journal of Neuroradiology April 2005, 26 (4) 869-874;
Michael M. Chow
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Thomas J. Masaryk
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Henry H. Woo
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Marc R. Mayberg
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Peter A. Rasmussen
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  • Article
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Article Figures & Data

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    TABLE 1:

    Clinical predictors (P values) of neurologic morbidity and mortality

    Clinical PredictorAll NeurocomplicationsPermanent NeurocomplicationsNeuromortality
    Age0.40140.73920.2549
    Sex0.08460.08250.0283
    Race:
        White1.00001.00001.0000
        Black1.00000.65481.0000
    Failed antiplatelet0.44991.00001.0000
    Failed coumadin ± heparin0.13120.06850.1417
    Comorbidity history:
        Cardiac0.31721.00000.5142
        Hypertension0.71100.69270.4130
        Diabetes0.03780.06040.5277
        Smoking0.54700.18661.0000
        Lipids0.87590.47700.5142
        CRF1.00001.00001.0000
        PVD0.71100.69271.0000
        Other1.00001.00000.1498
        >3 factors0.09310.47700.5142
    Preprocedural U/S velocity0.97460.65570.3544
    Postprocedural U/S velocity0.74090.80190.8061
    • Note: Boldface indicates statistical significance. (P <.10).

    • View popup
    TABLE 2:

    Procedural predictors (P values) of neurologic morbidity and mortality

    Procedural PredictorsAll NeurocomplicationsPermanent NeurocomplicationsNeurologic Mortality
    Initial vs. later experience0.64850.64811.0000
    Primary Interventionalist:
        TM0.26770.43550.5277
        JP0.44011.00001.0000
        JB0.38460.28210.0513
        PR0.68570.64861.0000
    Type of stent (velocity vs. other)0.83940.79830.4872
    Use of abciximab0.25910.69851.0000
    • Note: Boldface indicates statistical significance. (P <.10).

    • View popup
    TABLE 3:

    Angiographic predictors (P values) of neurologic morbidity and mortality

    Angiographic PredictorsAll NeurocomplicationsPermanent NeurocomplicationsNeurologic Mortality
    Basilar lesion0.26510.15521.0000
    Maximum stenosis:
        Percentage0.31860.46520.7075
        L/S ratio0.54600.24410.0518
        Residual0.13860.24590.1144
        Concentric0.45511.00001.0000
        Mori A0.72670.41100.1477
        Mori B1.00001.00000.0530
        Mori C0.62850.11671.0000
    Tandem or bilateral vertebral artery lesions:
        Presence0.96580.71390.5294
        Both treated1.00001.00001.0000
        >50%0.80021.00000.5134
    PICA distal to lesion0.32011.00001.0000
    AICA distal to lesion0.63720.63050.4444
    Presence of collaterals0.98080.43281.0000
    Ulceration1.00000.64930.3176
    • Note: Boldface indicates statistical significance. (P <.10).

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American Journal of Neuroradiology: 26 (4)
American Journal of Neuroradiology
Vol. 26, Issue 4
1 Apr 2005
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Stent-Assisted Angioplasty of Intracranial Vertebrobasilar Atherosclerosis: Midterm Analysis of Clinical and Radiologic Predictors of Neurological Morbidity and Mortality
Michael M. Chow, Thomas J. Masaryk, Henry H. Woo, Marc R. Mayberg, Peter A. Rasmussen
American Journal of Neuroradiology Apr 2005, 26 (4) 869-874;

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Stent-Assisted Angioplasty of Intracranial Vertebrobasilar Atherosclerosis: Midterm Analysis of Clinical and Radiologic Predictors of Neurological Morbidity and Mortality
Michael M. Chow, Thomas J. Masaryk, Henry H. Woo, Marc R. Mayberg, Peter A. Rasmussen
American Journal of Neuroradiology Apr 2005, 26 (4) 869-874;
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  • Stenting for intracranial stenosis: potential future for the prevention of disabling or fatal stroke
  • Symptom Differences and Pretreatment Asymptomatic Interval Affect Outcomes of Stenting for Intracranial Atherosclerotic Disease
  • Standard of practice: endovascular treatment of intracranial atherosclerosis
  • Wingspan Stents for the Treatment of Symptomatic Atherosclerotic Stenosis in Small Intracranial Vessels: Safety and Efficacy Evaluation
  • Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
  • Reporting standards for angioplasty and stent-assisted angioplasty for intracranial atherosclerosis
  • Reporting Standards for Angioplasty and Stent-Assisted Angioplasty for Intracranial Atherosclerosis
  • A Systematic Review on Outcome After Stenting for Intracranial Atherosclerosis
  • Subacute Stent Thrombosis in Intracranial Stenting
  • Emerging Endovascular Therapies for Symptomatic Intracranial Atherosclerotic Disease
  • Long-term outcome of elective stenting for symptomatic intracranial vertebrobasilar stenosis
  • US Multicenter Experience With the Wingspan Stent System for the Treatment of Intracranial Atheromatous Disease: Periprocedural Results
  • Perforator stroke after elective stenting of symptomatic intracranial stenosis
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