Article Figures & Data
Figures
- Fig 1.
Bar graph shows relative volume differences of several brain structures and relative difference of two-dimensional extension of the corpus callosum (call) in phenylketonuria versus the normal group. Pons and hippocampus (hippo) are the most severely affected structures. cbr = cerebrum.
Tables
Mean ± SD Minimum Maximum IQ 107.5 ± 18.7 64 148.0 IQperf 106.9 ± 17.7 76 149.0 IQverb 103.2 ± 16.1 56 134.0 Phecurr 1276.5 ± 490 205.7 2601.5 Phe5 308.6 ± 102.2 181.5 570.5 Phe12 399.3 ± 163.3 208.12 686.1 Note.—All volumes are given in mL. Phecurr, Phe5, and Phe12 are given in μmol/L. SD signifies standard deviation.
- TABLE 2:
Volumetric data of the analyzed brain structures and two-dimensional extension of the corpus callosum, PKU vs control group
Normal PKU P Value Mean value ± SD Mean value ± SD brain 1674.2 ± 99.7 1460.32 ± 179.72 <.001 cbr 1101.1 ± 95.5 960.64 ± 117.45 <.001 cbl 140.3 ± 11.3 132.30 ± 9.35 ns pons 34.9 ± 6.9 29.27 ± 6.38 <.005 call 6.31 ± 0.74 5.70 ± 0.71 <.005 hippo 6.13 ± 1.43 5.24 ± 0.80 <.001 caud 7.42 ± 0.85 7.32 ± 1.01 ns lent 9.96 ± 0.79 9.90 ± 0.70 ns thal 11.75 ± 0.67 12.10 ± 0.88 ns ventr 12.50 ± 2.15 13.71 ± 1.75 <.005 Note.—All volumes are given in mL; call is given in cm2; ns, no significance. Abbreviations identified in “Volumetric measurements” section.
