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OtherPEDIATRICS

Central Nervous System Extraosseous Ewing Sarcoma: Radiologic Manifestations of This Newly Defined Pathologic Entity

J.S. Pekala, S. Gururangan, J.M. Provenzale and S. Mukundan
American Journal of Neuroradiology March 2006, 27 (3) 580-583;
J.S. Pekala
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S. Gururangan
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J.M. Provenzale
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S. Mukundan Jr.
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Abstract

Summary: Although these entities are histologically similar, recent advances in molecular genetics have allowed the distinction of central nervous system extraosseous Ewing sarcoma (CNS-EES) from central primitive neuroectodermal tumors (c-PNET) including medulloblastoma and supratentorial PNET. We present 2 cases of pathologically confirmed CNS-EES. Knowledge of CNS-EES as a distinct entity enables the neuroradiologist to suggest the proper diagnosis and the need for special immuno-histochemical and molecular studies to confirm the diagnosis. Because treatment and prognosis are vastly different, the proper diagnosis of CNS-EES versus c-PNET is critical.

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American Journal of Neuroradiology: 27 (3)
American Journal of Neuroradiology
Vol. 27, Issue 3
March, 2006
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Central Nervous System Extraosseous Ewing Sarcoma: Radiologic Manifestations of This Newly Defined Pathologic Entity
J.S. Pekala, S. Gururangan, J.M. Provenzale, S. Mukundan
American Journal of Neuroradiology Mar 2006, 27 (3) 580-583;

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Central Nervous System Extraosseous Ewing Sarcoma: Radiologic Manifestations of This Newly Defined Pathologic Entity
J.S. Pekala, S. Gururangan, J.M. Provenzale, S. Mukundan
American Journal of Neuroradiology Mar 2006, 27 (3) 580-583;
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