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Research ArticleHEAD & NECK

Clinical Relevance of Musical Murmurs in Color-Coded Carotid and Transcranial Duplex Sonographies

S.-K. Lin, S.-J. Ryu, Y.-J. Chang and T.-H. Lee
American Journal of Neuroradiology August 2006, 27 (7) 1493-1497;
S.-K. Lin
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S.-J. Ryu
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Y.-J. Chang
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T.-H. Lee
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  • Fig. 1.
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    Fig. 1.

    A, Color-coded carotid duplex sonography reveals a tight stenotic internal carotid artery with concurrent musical murmurs (arrowheads) and markedly elevated turbulent flow velocities. Stenosis of the internal carotid artery is confirmed by digital subtraction cerebral angiography (arrow).

    B, Transcranial color-coded duplex sonography (TCCS) shows musical murmurs (arrowhead) in the proximal portion of the M2 segment of the right middle cerebral artery. MR angiography shows a tight stenotic artery (arrow) at the corresponding artery.

    C, TCCS discloses a color flash just below the bifurcation of the right anterior and middle cerebral arteries with continuous musical murmurs (arrowhead) sounding like a Chinese bamboo flute. Cerebral angiography shows a severe stenotic lesion at the right terminal internal carotid artery (arrow).

    D, TCCS shows concurrence of turbulent systolic spindle and musical murmurs of the left middle cerebral artery. MR angiography shows a tight stenotic lesion (arrow) at the corresponding artery.

    E and F, Transorbital detection of retro-orbital vessels in 2 patients with an angiography-proved carotid cavernous sinus fistula (right) show an abnormal color flash with musical murmurs (left).

  • Fig. 2.
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    Fig. 2.

    A, Doppler detection of a stenotic posterior cerebral artery with a high velocity scale (0–300 cm/s) shows elevated flow velocity with musical murmurs (arrows) embedded in the lower velocity area near the baseline.

    B, Proper adjustment of the Doppler velocity scale to a lower setting (±30 cm/s) clearly demonstrates the musical murmurs (arrowheads).

Tables

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    TABLE 1:

    Distribution and underlying vascular change of 66 musical murmurs in 60 patients

    Location of Musical MurmursSevere Stenosis (n = 58)*Collaterals (n = 5)C-C Fistula (n = 2)Moyamoya Disease (n = 1)
    Extracranial (n = 4)
        Internal carotid artery3
        Vertebral artery1
    Intracranial (n = 62)
        Retro-orbital area1†2
        Terminal internal carotid artery2
        Middle cerebral artery201
        Anterior cerebral artery9
        Posterior cerebral artery13
        Anterior communicating artery5‡
        Vertebral artery5
        Basilar artery4
    • Note:—C-C fistula indicates carotid cavernous sinus fistula.

    • * Number of musical murmurs.

    • † Transmitted from stenotic terminal internal carotid artery.

    • ‡ Were grouped into anterior cerebral artery by sonographic findings.

    • View popup
    TABLE 2:

    Clinical features and risk factors of 57 patients with musical murmurs due to stenotic vascular lesion

    Clinical PresentationTransient Ischemic AttackInfarctDizziness, Vertigo, and FaintnessTotal
    No. of patients941757
    Risk factors
        Hypertension834648
        Old age (>65 y)621734
        Diabetes mellitus216422
        Smoking512219
        Hyperlipidemia311317
        Ischemic heart disease17412
        Previous stroke0909
        Previous transient ischemic attack1102
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American Journal of Neuroradiology: 27 (7)
American Journal of Neuroradiology
Vol. 27, Issue 7
August 2006
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Clinical Relevance of Musical Murmurs in Color-Coded Carotid and Transcranial Duplex Sonographies
S.-K. Lin, S.-J. Ryu, Y.-J. Chang, T.-H. Lee
American Journal of Neuroradiology Aug 2006, 27 (7) 1493-1497;

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Clinical Relevance of Musical Murmurs in Color-Coded Carotid and Transcranial Duplex Sonographies
S.-K. Lin, S.-J. Ryu, Y.-J. Chang, T.-H. Lee
American Journal of Neuroradiology Aug 2006, 27 (7) 1493-1497;
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