The recent report in AJNR by dos Santos et al1 shows a case of MR imaging features in a child with horizontal gaze palsy with progressive scoliosis. This rare disorder has recently been shown by Jen et al2 to be secondary to defective brain stem crossing of descending corticospinal and somatosensory axons due to mutations in the ROBO3 gene that is necessary for axon crossing in the hindbrain.
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