Article Figures & Data
Figures
- Fig 1.
Case 1. A 27-year-old woman with a headache and hydrocephalus. Sagittal noncontrast T1-weighted 1.5T image (A) demonstrates a heterogeneously hyperintense mass involving the posterior commissure and pineal region. Postcontrast sagittal T1-weighted image (B) demonstrates subtle enhancement of the mass. Gradient-echo series (C) highlights calcification within the leftward displaced pineal gland but not within the mass itself. An arrow depicts a normal displaced pineal gland. There are no additional susceptibility effects to indicate hemorrhage, melanin, or mineralization elsewhere within the brain.
- Fig 2.
Cases 2, 3, and 4. Three women (aged 51 years, 50 years, and 51 years, respectively) presented with headaches and/or Parinaud syndrome. All cases are depicted by noncontrast T1-weighted sequences from 1.5T units (case 2 [A], case 3 [B], case 4 [C]). All 3 cases demonstrated intrinsic T1 hyperintensity and were centered on the posterior commissure.
- Fig 3.
Neuropathologic examination. Case 3, a patient with PTPR. All cases showed similar histologic and immunophenotypic features, including mixed solid and papillary areas (A). Cells in the solid areas displayed clear, vacuolated cytoplasm and tended to rosette around blood vessels. In the papillary areas (B), the tumor cells exhibited clear-to-eosinophilic cytoplasm and assumed a pseudostratified columnar-to-cuboidal epithelial appearance. The interface with adjacent brain parenchyma was sharp and pushing. All tumors exhibited an immunophenotype characteristic of PTPR, with strong expression of cytokeratin (C) and S-100 protein (D) (A and B, hematoxylin and eosin; C and D, immunoperoxidase with hematoxylin counter stain; original magnifications: A, x40; B, x200; C, x400; D, x400).
