Research ArticleBRAIN
Anoxic Injury-Associated Cerebral Hyperperfusion Identified with Arterial Spin-Labeled MR Imaging
J.M. Pollock, C.T. Whitlow, A.R. Deibler, H. Tan, J.H. Burdette, R.A. Kraft and J.A. Maldjian
American Journal of Neuroradiology August 2008, 29 (7) 1302-1307; DOI: https://doi.org/10.3174/ajnr.A1095
J.M. Pollock
C.T. Whitlow
A.R. Deibler
H. Tan
J.H. Burdette
R.A. Kraft

References
- ↵Arbelaez A, Castillo M, Mukherji SK. Diffusion-weighted MR imaging of global cerebral anoxia. AJNR Am J Neuroradiol 1999;20:999–1007
- ↵McKinney AM, Teksam M, Felice R, et al. Diffusion-weighted imaging in the setting of diffuse cortical laminar necrosis and hypoxic-ischemic encephalopathy. AJNR Am J Neuroradiol 2004;25:1659–65
- ↵Tha KK, Terae S, Yamamoto T, et al. Early detection of global cerebral anoxia: improved accuracy by high-b-value diffusion-weighted imaging with long echo time. AJNR Am J Neuroradiol 2005;26:1487–97
- ↵Cohan SL, Mun SK, Petite J, et al. Cerebral blood flow in humans following resuscitation from cardiac arrest. Stroke 1989;20:761–65
- ↵
- ↵
- ↵Giubilei F, Lenzi GL, Di Piero V, et al. Predictive value of brain perfusion single-photon emission computed tomography in acute ischemic stroke. Stroke 1990;21:895–900
- ↵Luh WM, Wong EC, Bandettini PA, et al. QUIPSS II with thin-slice TI1 periodic saturation: a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling. Magn Reson Med 1999;41:1246–54
- ↵Yang Y, Frank JA, Hou L, et al. Multislice imaging of quantitative cerebral perfusion with pulsed arterial spin labeling. Magn Reson Med 1998;39:825–32
- ↵Maldjian J, Laurienti P, Burdette J, et al. Clinical implementation of spin tag perfusion MRI. J Comput Assist Tomogr 2008 . In press.
- ↵Friston KJ, Holmes AP, Worsley KJ, et al. Statistical paramteric maps in functional imaging: a general linear approach. Hum Brain Mapp 1995;2:189–202
- ↵Detre JA, Leigh JS, Williams DS, et al. Perfusion imaging. Magn Reson Med 1992;23:37–45
- ↵Detre JA, Williams DS, Koretsky AP. Nuclear magnetic resonance determination of flow, lactate, and phosphate metabolites during amphetamine stimulation of the rat brain. NMR Biomed 1990;3:272–78
- ↵Alsop DC, Detre JA. Multisection cerebral blood flow MR imaging with continuous arterial spin labeling. Radiology 1998;208:410–16
- ↵Wong EC, Buxton RB, Frank LR. Quantitative perfusion imaging using arterial spin labeling. Neuroimaging Clin N Am 1999;9:333–42
- ↵Busija DW, Heistad DD. Factors involved in the physiological regulation of the cerebral circulation. Rev Physiol Biochem Pharmacol 1984;101:161–211
- ↵Faraci FM, Breese KR, Heistad DD. Cerebral vasodilation during hypercapnia. Role of glibenclamide-sensitive potassium channels and nitric oxide. Stroke 1994;25:1679–83
- ↵Madden JA. The effect of carbon dioxide on cerebral arteries. Pharmacol Ther 1993;59:229–50
- ↵Claassen JA, Zhang R, Fu Q, et al. Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing. J Appl Physiol 2007;102:870–77
- ↵Hanigan WC, Aldag J, Sabo RA, et al. Strangulation injuries in children. Part 2. Cerebrovascular hemodynamics J Trauma 1996;40:73–77
- Kastrup A, Li TQ, Glover GH, et al. Cerebral blood flow-related signal changes during breath-holding. AJNR Am J Neuroradiol 1999;20:1233–38
- Vovk A, Cunningham DA, Kowalchuk JM, et al. Cerebral blood flow responses to changes in oxygen and carbon dioxide in humans. Can J Physiol Pharmacol 2002;80:819–27
- Ito H, Kanno I, Ibaraki M, et al. Effect of aging on cerebral vascular response to PaCO2 changes in humans as measured by positron emission tomography. J Cereb Blood Flow Metab 2002;22:997–1003
- Noth U, Kotajima F, Deichmann R, et al. Mapping of the cerebral vascular response to hypoxia and hypercapnia using quantitative perfusion MRI at 3 T. NMR Biomed.2007 Sep 13 [Epub ahead of print]
- ↵
- ↵Paulson OB, Strandgaard S, Edvinsson L. Cerebral autoregulation. Cerebrovasc Brain Metab Rev 1990;2:161–92
- ↵
- ↵Sundgreen C, Larsen FS, Herzog TM, et al. Autoregulation of cerebral blood flow in patients resuscitated from cardiac arrest. Stroke 2001;32:128–32
- Lillywhite N, Matta B. Loss of cerebral pressure autoregulation and vasoreactivity to carbon dioxide after cerebral hypoxia. Anaesth Intensive Care 1996;24:91–93
- Nishizawa H, Kudoh I. Cerebral autoregulation is impaired in patients resuscitated after cardiac arrest. Acta Anaesthesiol Scand 1996;40:1149–53
- Immink RV, van den Born BJ, van Montfrans GA, et al. Impaired cerebral autoregulation in patients with malignant hypertension. Circulation 2004;110:2241–45
- Cruz J, Jaggi JL, Hoffstad OJ. Cerebral blood flow, vascular resistance, and oxygen metabolism in acute brain trauma: redefining the role of cerebral perfusion pressure? Crit Care Med 1995;23:1412–17
- Agnoli A, Fieschi C, Bozzao L, et al. Autoregulation of cerebral blood flow. Studies during drug-induced hypertension in normal subjects and in patients with cerebral vascular diseases. Circulation 1968;38:800–12
- ↵
- ↵Schaafsma A, de Jong BM, Bams JL, et al. Cerebral perfusion and metabolism in resuscitated patients with severe post-hypoxic encephalopathy. J Neurol Sci 2003;210:23–30
- ↵Deibler A, Pollock JM, Kraft R, et al. M. Arterial spin-labeling in routine clinical practice part 3: hypoperfusion patterns. AJNR Am J Neuroradiol.2008 Mar 20 [Epub ahead of print]
- ↵Panerai RB. Assessment of cerebral pressure autoregulation in humans–a review of measurement methods. Physiol Meas 1998;19:305–38
- Bickler PE. Cerebral anoxia tolerance in turtles: regulation of intracellular calcium and pH. Am J Physiol 1992;263:R1298–302
- Bickler PE. Effects of temperature and anoxia on regional cerebral blood flow in turtles. Am J Physiol 1992;262:R538–41
- ↵Laudignon N, Farri E, Beharry K, et al. Influence of adenosine on cerebral blood flow during hypoxic hypoxia in the newborn piglet. J Appl Physiol 1990;68:1534–41
- ↵Paulson OB, Lassen NA, Skinhoj E. Regional cerebral blood flow in apoplexy without arterial occlusion. Neurology 1970;20:125–38
- ↵Wang J, Licht DJ, Jahng GH, et al. Pediatric perfusion imaging using pulsed arterial spin labeling. J Magn Reson Imaging 2003;18:404–13
- ↵Wintermark M, Lepori D, Cotting J, et al. Brain perfusion in children: evolution with age assessed by quantitative perfusion computed tomography. Pediatrics 2004;113:1642–52
- ↵Hoesch RE, Geocadin RG. Therapeutic hypothermia for global and focal ischemic brain injury—a cool way to improve neurologic outcomes. Neurologist 2007;13:331–42
- Agnew DM, Koehler RC, Guerguerian AM, et al. Hypothermia for 24 hours after asphyxic cardiac arrest in piglets provides striatal neuroprotection that is sustained 10 days after rewarming. Pediatr Res 2003;54:253–62
- Shaffner DH, Eleff SM, Koehler RC, et al. Effect of the no-flow interval and hypothermia on cerebral blood flow and metabolism during cardiopulmonary resuscitation in dogs. Stroke 1998;29:2607–15
- ↵Rutherford MA, Azzopardi D, Whitelaw A, et al. Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy. Pediatrics 2005;116:1001–06
- ↵Wijdicks EF, Campeau NG, Miller GM. MR imaging in comatose survivors of cardiac resuscitation. AJNR Am J Neuroradiol 2001;22:1561–65
- ↵Paulson OB, Olesen J, Christensen MS. Restoration of autoregulation of cerebral blood flow by hypocapnia. Neurology 1972;22:286–93
In this issue
Advertisement
Anoxic Injury-Associated Cerebral Hyperperfusion Identified with Arterial Spin-Labeled MR Imaging
J.M. Pollock, C.T. Whitlow, A.R. Deibler, H. Tan, J.H. Burdette, R.A. Kraft, J.A. Maldjian
American Journal of Neuroradiology Aug 2008, 29 (7) 1302-1307; DOI: 10.3174/ajnr.A1095
Jump to section
Related Articles
- No related articles found.
Cited By...
- Anoxic Brain Injury Detection with the Normalized Diffusion to ASL Perfusion Ratio: Implications for Blood-Brain Barrier Injury and Permeability
- Arterial Spin Labeling Perfusion Magnetic Resonance Imaging Performed in Acute Perinatal Stroke Reveals Hyperperfusion Associated With Ischemic Injury
- Medial Occipital Lobe Hyperperfusion Identified by Arterial Spin-Labeling: A Poor Prognostic Sign in Patients with Hypoxic-Ischemic Encephalopathy
- Brain Perfusion in Encephalopathic Newborns after Therapeutic Hypothermia
- Thalamocortical Dysfunction and Thalamic Injury after Asphyxial Cardiac Arrest in Developing Rats
- Novel MRI Approaches for Assessing Cerebral Hemodynamics in Ischemic Cerebrovascular Disease
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement