Article Figures & Data
Figures
- Fig 1.
A−C, DSA with selective ICA injection pre- (A) and postembolization (B) at the origin of the ICA, resulting in an occlusion of the right MCA (arrow in B). C, DWI performed 4 hours later confirms the presence of a right MCA infarct (arrow). D, C-arm CT and PCT (E) demonstrate corresponding decreased CBV as determined both by the color maps and measured values in the respective regions of interest. CBV values are in milliliters per 100 grams of brain tissue.
- Fig 2.
A and B, DSA with selective ICA injection pre-embolization demonstrates tortuosity of the ICA (asterisk in A). Embolization was performed near the origin of the right MCA, from a vertebral artery approach leading to occlusion of the proximal MCA. MCA infarct (arrow) was validated by DWI (C) done 4 hours after embolization. C-arm CT (D) and PCT (E) reveal corresponding decreased CBV as determined both by the color maps and measured values in the respective regions of interest.
Tables
Mean CBV (mL/100 g) P Valueb PCT infarct vs PCT normal 0.814/1.378 .0039 C-arm 1 infarct vs C-arm 1 normalc 0.662/1.429 .0008 C-arm 1.5 infarct vs C-arm 1.5 normald 0.561/1.163 .0014 PCT infarct vs C-arm 1 infarct 0.814/0.662 .158 PCT infarct vs C-arm 1.5 infarct 0.121/0.178 .072 PCT normal vs C-arm 1 normalc 1.378/1.429 .791 PCT normal vs C-arm 1.5 normal 1.378/1.163 .241 a Mean CBV values in the regions of interest within the infarcted territory (infarct) and in the normal contralateral side (normal) in the 10 canine experiments.
b Paired 2-sample t test.
c 1 indicates 1 mL/s; C-arm 1, values from the first C-arm CT acquisition.
d C-arm 2 indicates values from the second C-arm CT acquisition.
Mean CBV Ratio (infarct/normal) P Valueb PCT normal vs C-arm 1 normalc 0.626/0.496 .199 PCT normal vs C-arm 1.5 normald 0.626/0.467 .166 a Mean ratio of region-of-interest values between the infarcted territory (infarct) and the normal contralateral side (normal) in the 10 canine experiments.
b Paired 2-sample t test.
c 1 indicates 1 mL/s.
d 1.5 indicates 1.5 mL/s.
Reader 1 Reader 2 Reader 3 Mean TP readings of PCT 75.0% 70% 75% 73.3% TP readings of C-arm CT 83.3% 83.3% 86.7% 84.4% FP readings of PCT 0% 5% 0% 1.7% FP readings of C-arm CT 0% 3.3% 6.7% 3.3% FN readings of PCT 25% 25% 25% 25% FN readings of C-arm CT 16.7% 13.3% 6.7% 12.2% a Percentage of TP (infarct was correctly identified), FP (CBV abnormality identified in a location where there was no DWI abnormality), and FN (no abnormality identified in location where there was a DWI abnormality) readings are given for each reader individually and the mean of all 3 readers. C-arm CT readings demonstrate a better correlation with the criterion standard DWI. Most interesting, the rate of FP readings is very low. Please note the discrepancy of FN PCT and FN C-arm CT readings.
In this issue
Jump to section
Related Articles
Cited By...
- Exploring the Value of Using Color-Coded Quantitative DSA Evaluation on Bilateral Common Carotid Arteries in Predicting the Reliability of Intra-Ascending Aorta Flat Detector CT-CBV Maps
- A Novel Technique for the Measurement of CBF and CBV with Robot-Arm-Mounted Flat Panel CT in a Large-Animal Model
- C-Arm CT Measurement of Cerebral Blood Volume and Cerebral Blood Flow Using a Novel High-Speed Acquisition and a Single Intravenous Contrast Injection
- Initial experience with a combined multidetector CT and biplane digital subtraction angiography suite with a single interactive table for the diagnosis and treatment of neurovascular disease
- Frameless multimodal image guidance of localized convection-enhanced delivery of therapeutics in the brain
- C-Arm CT Measurement of Cerebral Blood Volume Using Intra-Arterial Injection of Contrast Medium: An Experimental Study in Canines
- Preclinical acute ischemic stroke modeling
- Feasibility of Cerebral Blood Volume Mapping by Flat Panel Detector CT in the Angiography Suite: First Experience in Patients with Acute Middle Cerebral Artery Occlusions
- Quantitative Evaluation of C-Arm CT Cerebral Blood Volume in a Canine Model of Ischemic Stroke
- Advances in Stroke: Advances in Interventional Neuroradiology
- Applicability of Tableside Flat Panel Detector CT Parenchymal Cerebral Blood Volume Measurement in Neurovascular Interventions: Preliminary Clinical Experience
- Cerebral CT Perfusion Using an Interventional C-Arm Imaging System: Cerebral Blood Flow Measurements
- Angiographic CT after Intravenous Contrast Agent Application: A Noninvasive Follow-Up Tool after Intracranial Angioplasty and Stenting
- Flat Detector CT in the Evaluation of Brain Parenchyma, Intracranial Vasculature, and Cerebral Blood Volume: A Pilot Study in Patients with Acute Symptoms of Cerebral Ischemia