Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
    • COVID-19 Content and Resources
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
    • COVID-19 Content and Resources
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Research ArticleInterventionalE
Open Access

Higher Rates of Mortality but Not Morbidity Follow Intracranial Mechanical Thrombectomy in the Elderly

Y. Loh, D. Kim, Z.-S. Shi, S. Tateshima, P.M. Vespa, N.R. Gonzalez, S. Starkman, J.L. Saver, R. Jahan, D.S. Liebeskind, G.R. Duckwiler and F. Viñuela
American Journal of Neuroradiology August 2010, 31 (7) 1181-1185; DOI: https://doi.org/10.3174/ajnr.A2079
Y. Loh
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. Kim
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Z.-S. Shi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Tateshima
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.M. Vespa
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N.R. Gonzalez
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Starkman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.L. Saver
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. Jahan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D.S. Liebeskind
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G.R. Duckwiler
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F. Viñuela
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Gobin YP,
    2. Starkman S,
    3. Duckwiler GR,
    4. et al
    . MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke 2004;35:2848–54
    Abstract/FREE Full Text
  2. 2.↵
    1. Smith WS,
    2. Sung G,
    3. Starkman S,
    4. et al.
    , for the MERCI Trial Investigators. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36:1432–38
    Abstract/FREE Full Text
  3. 3.↵
    1. Day J
    . Population Projections of the United States by Age, Sex, Race, and Hispanic Origin: 1995–2050. Washington, DC: US Bureau of the Census; 1996. Current Population Reports, Series P25–1130
  4. 4.↵
    1. Brown RD,
    2. Whisnant JP,
    3. Sicks JD,
    4. et al
    . Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989. Stroke 1996;27:373–80
    PubMedWeb of Science
  5. 5.↵
    1. Sharma JC,
    2. Fletcher S,
    3. Vassallo M
    . Strokes in the elderly: higher acute and 3 month mortality—an explanation. Cerebrovasc Dis 1999;9:2–9
    PubMedWeb of Science
  6. 6.↵
    1. Arnold M,
    2. Schroth G,
    3. Nedeltchev K,
    4. et al
    . Intra-arterial thrombolysis in 100 patients with acute stroke due to middle cerebral artery occlusion. Stroke 2002;33:1828–33
    Abstract/FREE Full Text
  7. 7.↵
    1. Kim D,
    2. Ford GA,
    3. Kidwell CS,
    4. et al
    . Intra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 years. AJNR Am J Neurorad 2007;28:159–63
  8. 8.↵
    1. Tanne D,
    2. Gorman M,
    3. Bates V,
    4. et al
    . Intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 80 years and older: the TPA stroke survey experience. Stroke 2000;31:370–75
    Abstract/FREE Full Text
  9. 9.↵
    1. Khatri P,
    2. Neff J,
    3. Broderick JP,
    4. et al.
    , for the IMS-I Investigators. Revascularization end points in stroke interventional trials: recanalization versus reperfusion in IMS-I. Stroke 2005;36:2400–03
    Abstract/FREE Full Text
  10. 10.↵
    1. Hacke W,
    2. Kaste M,
    3. Fieschi C,
    4. et al.
    , for the ECASS Study Group. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: The European Cooperative Acute Stroke Study (ECASS). JAMA 1995;274:1017–25
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Kim D,
    2. Jahan R,
    3. Saver JL,
    4. et al.
    , for the MERCI and Multi MERCI Investigators. Mechanical thrombectomy with the Merci retriever for acute stroke in very elderly patients. In: Proceedings of the Fourth Annual Meeting of the American Society of Interventional and Therapeutic Neuroradiology, Dana Point, California, August 1, 2007
  12. 12.↵
    1. Furlan A,
    2. Higashida R,
    3. Weschler L,
    4. et al
    . Intra-arterial prourokinase for acute ischemic stroke: The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 1999;282:2003–11
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Kidwell CS,
    2. Saver JL,
    3. Carneado J,
    4. et al
    . Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke 2002;33:717–24
    Abstract/FREE Full Text
  14. 14.↵
    1. Kase CS,
    2. Furlan AJ,
    3. Wechsler LR,
    4. et al
    . Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial. Neurology 2001;57:1603–10
    Abstract/FREE Full Text
  15. 15.↵
    1. Tanne D,
    2. Kasner SE,
    3. Demchuk AM,
    4. et al
    . Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. Circulation 2002;105:1679–85
    Abstract/FREE Full Text
  16. 16.↵
    1. Larrue V,
    2. von Kummer RR,
    3. Müller A,
    4. et al
    . Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke 2001;32:438–41
    Abstract/FREE Full Text
  17. 17.↵
    1. Bang OY,
    2. Saver JL,
    3. Buck BH,
    4. et al.
    , for the UCLA Collateral Investigators. Impact of collateral flow on tissue fate in acute ischaemic stroke. J Neurol Neurosurg Psychiatry 2008;79:625–29. Epub 2007 Dec 12
    Abstract/FREE Full Text
  18. 18.↵
    1. Christoforidis GA,
    2. Karakasis C,
    3. Mohammad Y,
    4. et al
    . Predictors of hemorrhage following intra-arterial thrombolysis for acute ischemic stroke: the role of pial collateral formation. AJNR Am J Neuroradiol 2009;30:165–70
    Abstract/FREE Full Text
  19. 19.↵
    1. Nedelmann M,
    2. Wilhelm-Schwenkmezger T,
    3. Alessandri B,
    4. et al
    . Cerebral embolic ischemia in rats: correlation of stroke severity and functional deficit as important outcome parameter. Brain Res 2007;1130:188–96. Epub 2006 Dec 8
    CrossRefPubMed
  20. 20.↵
    1. Nighoghossian N,
    2. Hermier M,
    3. Adeleine P,
    4. et al
    . Baseline magnetic resonance imaging parameters and stroke outcome in patients treated by intravenous tissue plasminogen activator. Stroke 2003;34:458–63
    Abstract/FREE Full Text
  21. 21.↵
    1. Tomsick T
    . TIMI, TIBI, TICI: I came, I saw, I got confused. AJNR Am J Neuroradiol 2007;28:382–84
    FREE Full Text
  22. 22.↵
    1. Higashida R,
    2. Furlan A,
    3. Roberts H,
    4. et al.
    , for the Technology Assessment Committees of the American Society of Interventional and Therapeutic Neuroradiology and the Society of Interventional Radiology. Trial design and reporting standards for intraarterial cerebral thrombolysis for acute ischemic stroke. J Vasc Interv Radiol 2003;14:945–46
    PubMed
  23. 23.↵
    1. Tejima E,
    2. Katayama Y,
    3. Suzuki Y,
    4. et al
    . Hemorrhagic transformation after fibrinolysis with tissue plasminogen activator: evaluation of role of hypertension with rat thromboembolic stroke model. Stroke 2001;32:1336–40
    Abstract/FREE Full Text
  24. 24.↵
    1. Elewa HF,
    2. Kozak A,
    3. Johnson MH,
    4. et al
    . Blood pressure lowering after experimental cerebral ischemia provides neurovascular protection. J Hypertens 2007;25:855–59
    PubMed
  25. 25.↵
    1. Greer DM,
    2. Funk SE,
    3. Reaven NL,
    4. et al
    . Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis. Stroke 2008;39:3029–35
    Abstract/FREE Full Text
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 31 (7)
American Journal of Neuroradiology
Vol. 31, Issue 7
1 Aug 2010
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Higher Rates of Mortality but Not Morbidity Follow Intracranial Mechanical Thrombectomy in the Elderly
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Higher Rates of Mortality but Not Morbidity Follow Intracranial Mechanical Thrombectomy in the Elderly
Y. Loh, D. Kim, Z.-S. Shi, S. Tateshima, P.M. Vespa, N.R. Gonzalez, S. Starkman, J.L. Saver, R. Jahan, D.S. Liebeskind, G.R. Duckwiler, F. Viñuela
American Journal of Neuroradiology Aug 2010, 31 (7) 1181-1185; DOI: 10.3174/ajnr.A2079

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Higher Rates of Mortality but Not Morbidity Follow Intracranial Mechanical Thrombectomy in the Elderly
Y. Loh, D. Kim, Z.-S. Shi, S. Tateshima, P.M. Vespa, N.R. Gonzalez, S. Starkman, J.L. Saver, R. Jahan, D.S. Liebeskind, G.R. Duckwiler, F. Viñuela
American Journal of Neuroradiology Aug 2010, 31 (7) 1181-1185; DOI: 10.3174/ajnr.A2079
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis
  • Endovascular treatment in older adults with acute ischemic stroke in the MR CLEAN Registry
  • An international multicenter retrospective study to survey the landscape of thrombectomy in the treatment of anterior circulation acute ischemic stroke: outcomes with respect to age
  • Using machine learning to optimize selection of elderly patients for endovascular thrombectomy
  • Outcomes of endovascular thrombectomy in the elderly: a 'real-world multicenter study
  • Thrombectomy for acute ischemic stroke in the elderly: a 'real world experience
  • Efficacy of intra-arterial therapy in the elderly requires further study
  • Efficacy of endovascular stroke management in elderly patients
  • Patient Selection for Stroke Endovascular Therapy-- DWI-ASPECTS Thresholds Should Vary among Age Groups: Insights from the RECOST Study
  • Influence of Age on Clinical and Revascularization Outcomes in the North American Solitaire Stent-Retriever Acute Stroke Registry
  • Multimodal endovascular management of acute ischemic stroke in patients over 75 years old is safe and effective
  • Elderly Patients Are at Higher Risk for Poor Outcomes After Intra-Arterial Therapy
  • Patient Outcomes With Endovascular Embolectomy Therapy for Acute Ischemic Stroke: A Study of the National Inpatient Sample: 2006 to 2008
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Use of the Woven EndoBridge Device for Sidewall Aneurysms: Systematic Review and Meta-analysis
  • Association between Infarct Location and Hemorrhagic Transformation of Acute Ischemic Stroke following Successful Recanalization after Mechanical Thrombectomy
  • Viz.ai Implementation of Stroke Augmented Intelligence and Communications Platform to Improve Indicators and Outcomes for a Comprehensive Stroke Center and Network
Show more Interventional

Similar Articles

Advertisement

News and Updates

  • Lucien Levy Best Research Article Award
  • Thanks to our 2022 Distinguished Reviewers
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2023 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire