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Research ArticleInterventionalT
Open Access

A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices

I. Kan, I. Yuki, Y. Murayama, F.A. Viñuela, R.H. Kim, H.V. Vinters and F. Viñuela
American Journal of Neuroradiology October 2010, 31 (9) 1741-1743; DOI: https://doi.org/10.3174/ajnr.A1991
I. Kan
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I. Yuki
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Y. Murayama
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F.A. Viñuela
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R.H. Kim
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H.V. Vinters
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F. Viñuela
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SUMMARY:

We report the development of a novel technique of thrombus preparation for use in a swine model for evaluation of thrombectomy devices. The experimental thrombus prepared using plain sedimentation showed mechanical stability due to its solid fibrin-rich component. The thrombus also showed histologic similarity to the typical thromboemboli recovered from patients with stroke in the course of therapeutic thrombectomy. This new technique may be beneficial for preclinical evaluation of thrombectomy devices.

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American Journal of Neuroradiology: 31 (9)
American Journal of Neuroradiology
Vol. 31, Issue 9
1 Oct 2010
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A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices
I. Kan, I. Yuki, Y. Murayama, F.A. Viñuela, R.H. Kim, H.V. Vinters, F. Viñuela
American Journal of Neuroradiology Oct 2010, 31 (9) 1741-1743; DOI: 10.3174/ajnr.A1991

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A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices
I. Kan, I. Yuki, Y. Murayama, F.A. Viñuela, R.H. Kim, H.V. Vinters, F. Viñuela
American Journal of Neuroradiology Oct 2010, 31 (9) 1741-1743; DOI: 10.3174/ajnr.A1991
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Cited By...

  • Novel methodology to replicate clot analogs with diverse composition in acute ischemic stroke
  • Histopathologic Evaluation of Arterial Wall Response to 5 Neurovascular Mechanical Thrombectomy Devices in a Swine Model
  • A Swine Model to Analyze Arterial Structural Changes Induced by Mechanical Thrombectomy
  • The hyperdense vessel sign on CT predicts successful recanalization with the Merci device in acute ischemic stroke
  • Characterization of Arterial Thrombus Composition by Magnetic Resonance Imaging in a Swine Stroke Model
  • A Comparison of 2 Stroke Devices: The New Aperio Clot-Removal Device and the Solitaire AB/FR
  • The Impact of Thromboemboli Histology on the Performance of a Mechanical Thrombectomy Device
  • Mechanical Characterization of Thromboemboli in Acute Ischemic Stroke and Laboratory Embolus Analogs
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More in this TOC Section

  • Clinical Significance of Prehospital Telecommunication Defined as the Critical Stroke Call Pathway in Acute Ischemic Stroke Requiring Intra-Arterial Recanalization Therapy
  • ADC Level is Related to DWI Reversal in Patients Undergoing Mechanical Thrombectomy: A Retrospective Cohort Study
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