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Research ArticleBrain
Open Access

Overcoming the Clinical–MR Imaging Paradox of Multiple Sclerosis: MR Imaging Data Assessed with a Random Forest Approach

K. Kac̆ar, M.A. Rocca, M. Copetti, S. Sala, Š. Mesaroš, T. Stosić Opinćal, D. Caputo, M. Absinta, J. Drulović, V.S. Kostić, G. Comi and M. Filippi
American Journal of Neuroradiology December 2011, 32 (11) 2098-2102; DOI: https://doi.org/10.3174/ajnr.A2864
K. Kac̆ar
aFrom the Neuroimaging Research Unit (K.K., M.A.R., S.S., S.M., M.A., M.F.)
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M.A. Rocca
aFrom the Neuroimaging Research Unit (K.K., M.A.R., S.S., S.M., M.A., M.F.)
bInstitute of Experimental Neurology, Division of Neuroscience, and Department of Neurology (M.A.R., M.A., G.C., M.F.), Scientific Institute and University Hospital San Raffaele, Milan, Italy
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M. Copetti
cthe Biostatistics Unit (M.C.), Istituto di Ricovero e Cura a Carattere Scientifico-Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy
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S. Sala
aFrom the Neuroimaging Research Unit (K.K., M.A.R., S.S., S.M., M.A., M.F.)
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Š. Mesaroš
aFrom the Neuroimaging Research Unit (K.K., M.A.R., S.S., S.M., M.A., M.F.)
dClinics of Neurology (S.M., J.D., V.S.K.)
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T. Stosić Opinćal
eRadiology (T.S.O.), Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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D. Caputo
fDepartment of Neurology (D.C.), Scientific Institute Fondazione Don Gnocchi, Milan, Italy.
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M. Absinta
aFrom the Neuroimaging Research Unit (K.K., M.A.R., S.S., S.M., M.A., M.F.)
bInstitute of Experimental Neurology, Division of Neuroscience, and Department of Neurology (M.A.R., M.A., G.C., M.F.), Scientific Institute and University Hospital San Raffaele, Milan, Italy
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J. Drulović
dClinics of Neurology (S.M., J.D., V.S.K.)
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V.S. Kostić
dClinics of Neurology (S.M., J.D., V.S.K.)
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G. Comi
bInstitute of Experimental Neurology, Division of Neuroscience, and Department of Neurology (M.A.R., M.A., G.C., M.F.), Scientific Institute and University Hospital San Raffaele, Milan, Italy
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M. Filippi
aFrom the Neuroimaging Research Unit (K.K., M.A.R., S.S., S.M., M.A., M.F.)
bInstitute of Experimental Neurology, Division of Neuroscience, and Department of Neurology (M.A.R., M.A., G.C., M.F.), Scientific Institute and University Hospital San Raffaele, Milan, Italy
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Data supplements

  • Supplemental Online Appendix and Tables

    Files in this Data Supplement:

    • Online Appendix and Tables 1-4 (PDF) -
      Appendix: see PDF

      Online Table 1: Main demographic and clinical findings from the cohorts of patients with MS studied

      Online Table 2: Number of patients with impairment in the different functional systems of the EDSS

      Online Table 3: Structural MR imaging findings from healthy controls and patients with MS studied

      Online Table 4: Results of the random forest analysis
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American Journal of Neuroradiology: 32 (11)
American Journal of Neuroradiology
Vol. 32, Issue 11
1 Dec 2011
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Overcoming the Clinical–MR Imaging Paradox of Multiple Sclerosis: MR Imaging Data Assessed with a Random Forest Approach
K. Kac̆ar, M.A. Rocca, M. Copetti, S. Sala, Š. Mesaroš, T. Stosić Opinćal, D. Caputo, M. Absinta, J. Drulović, V.S. Kostić, G. Comi, M. Filippi
American Journal of Neuroradiology Dec 2011, 32 (11) 2098-2102; DOI: 10.3174/ajnr.A2864

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Overcoming the Clinical–MR Imaging Paradox of Multiple Sclerosis: MR Imaging Data Assessed with a Random Forest Approach
K. Kac̆ar, M.A. Rocca, M. Copetti, S. Sala, Š. Mesaroš, T. Stosić Opinćal, D. Caputo, M. Absinta, J. Drulović, V.S. Kostić, G. Comi, M. Filippi
American Journal of Neuroradiology Dec 2011, 32 (11) 2098-2102; DOI: 10.3174/ajnr.A2864
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