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Research ArticleBrainC

Suspicious Neuroimaging Pattern of Thrombotic Microangiopathy

T.N. Ellchuk, L.M. Shah, R.H. Hewlett and A.G. Osborn
American Journal of Neuroradiology April 2011, 32 (4) 734-738; DOI: https://doi.org/10.3174/ajnr.A2351
T.N. Ellchuk
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L.M. Shah
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R.H. Hewlett
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A.G. Osborn
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Abstract

SUMMARY: The TMAs are a group of microvascular occlusive disorders characterized by thrombocytopenia and intravascular hemolysis. Literature review reveals a spectrum of neuroimaging findings, including a single case report of multifocal hemorrhagic infarctions. We present a series of 12 patients with TMA demonstrating a similar pattern of multifocal cortical and subcortical hemorrhagic infarctions.

Abbreviations

ADC
apparent diffusion coefficient
AML
acute myelogenous leukemia
CLL
chronic lymphocytic leukemia
CNS
central nervous system
CTV
CT venography
DIC
disseminated intravascular coagulation
DWI
diffusion-weighted imaging
GRE
gradient recalled-echo
HIV
human immunodeficiency virus
HUS
hemolytic uremic syndrome
mHTN
malignant hypertension
MRI
MR imaging
MRV
MR venography
PRES
posterior reversible encephalopathy syndrome
SWI
susceptibility-weighted imaging
TMA
thrombotic microangiopathy
TTP
thrombotic thrombocytopenic purpura
vWF
von Willebrand factor
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American Journal of Neuroradiology: 32 (4)
American Journal of Neuroradiology
Vol. 32, Issue 4
1 Apr 2011
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Suspicious Neuroimaging Pattern of Thrombotic Microangiopathy
T.N. Ellchuk, L.M. Shah, R.H. Hewlett, A.G. Osborn
American Journal of Neuroradiology Apr 2011, 32 (4) 734-738; DOI: 10.3174/ajnr.A2351

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Suspicious Neuroimaging Pattern of Thrombotic Microangiopathy
T.N. Ellchuk, L.M. Shah, R.H. Hewlett, A.G. Osborn
American Journal of Neuroradiology Apr 2011, 32 (4) 734-738; DOI: 10.3174/ajnr.A2351
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