Quantitative Assessment of Brain Stem and Cerebellar Atrophy in Spinocerebellar Ataxia Types 3 and 6: Impact on Clinical Status

References

1. 1.↵
   1. Schöls L,
   2. Bauer P,
   3. Schmidt T,
   4. et al

   . Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. Lancet Neurol 2004; 3: 291–304

   CrossRefPubMedWeb of Science
2. 2.↵
   1. Brenneis C,
   2. Bosch SM,
   3. Schocke M,
   4. et al

   . Atrophy pattern in SCA2 determined by voxel-based morphometry. Neuroreport 2003; 14: 1799–802

   CrossRefPubMedWeb of Science
3. 3.↵
   1. Della Nave R,
   2. Ginestroni A,
   3. Tessa C,
   4. et al

   . Brain white matter damage in SCA1 and SCA2: an in vivo study using voxel-based morphometry, histogram analysis of mean diffusivity and tract-based spatial statistics. Neuroimage 2008; 43: 10–19

   CrossRefPubMed
4. 4.↵
   1. Klockgether T,
   2. Skalej M,
   3. Wedekind D,
   4. et al

   . Autosomal dominant cerebellar ataxia type I: MRI-based volumetry of posterior fossa structures and basal ganglia in spinocerebellar ataxia types 1, 2 and 3. Brain 1998; 121: 1687–93

   Abstract/FREE Full Text
5. 5.↵
   1. Schulz JB,
   2. Borkert J,
   3. Wolf S,
   4. et al

   . Visualization, quantification and correlation of brain atrophy with clinical symptoms in spinocerebellar ataxia types 1, 3 and 6. Neuroimage 2010; 49: 158–68

   CrossRefPubMedWeb of Science
6. 6.↵
   1. Rub U,
   2. Brunt ER,
   3. Deller T

   . New insights into the pathoanatomy of spinocerebellar ataxia type 3 (Machado-Joseph disease). Curr Opin Neurol 2008;21:111–16

   PubMedWeb of Science
7. 7.↵
   1. Butteriss D,
   2. Chinnery P,
   3. Birchall D

   . Radiological characterization of spinocerebellar ataxia type 6. Br J Radiol 2005; 78: 694–96

   Abstract/FREE Full Text
8. 8.↵
   1. Murata Y,
   2. Kawakami H,
   3. Yamaguchi S,
   4. et al

   . Characteristic magnetic resonance imaging findings in spinocerebellar ataxia 6. Arch Neurol 1998; 55: 1348–52

   CrossRefPubMedWeb of Science
9. 9.↵
   1. Satoh JI,
   2. Tokumoto H,
   3. Yukitake M,
   4. et al

   . Spinocerebellar ataxia type 6: MRI of three Japanese patients. Neuroradiology 1998; 40: 222–27

   CrossRefPubMedWeb of Science
10. 10.↵
    1. Murata Y,
    2. Yamaguchi S,
    3. Kawakami H,
    4. et al

    . Characteristic magnetic resonance imaging findings in Machado-Joseph disease. Arch Neurol 1998; 55: 33–37

    CrossRefPubMedWeb of Science
11. 11.↵
    1. Yoshizawa T,
    2. Watanabe M,
    3. Frusho K,
    4. et al

    . Magnetic resonance imaging demonstrates differential atrophy of pontine base and tegmentum in Machado-Joseph disease. J Neurol Sci 2003; 215: 45–50

    CrossRefPubMed
12. 12.↵
    1. Rub U,
    2. Brunt ER,
    3. Petrasch-Parwez E,
    4. et al

    . Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7. Neuropathol Appl Neurobiol 2006; 32: 635–49

    CrossRefPubMedWeb of Science
13. 13.↵
    1. Gierga K,
    2. Schelhaas HJ,
    3. Brunt ER,
    4. et al

    . Spinocerebellar ataxia type 6 (SCA6): neurodegeneration goes beyond the known brain predilection sites. Neuropathol Appl Neurobiol 2009; 35: 515–27

    CrossRefPubMed
14. 14.↵
    1. Trouillas P,
    2. Takayanagi T,
    3. Hallett M,
    4. et al

    . International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome: the Ataxia Neuropharmacology Committee of the World Federation of Neurology. J Neurol Sci 1997; 145: 205–11

    CrossRefPubMedWeb of Science
15. 15.↵
    1. Lukas C,
    2. Hahn HK,
    3. Bellenberg B,
    4. et al

    . Spinal cord atrophy in spinocerebellar ataxia type 3 and 6: impact on clinical disability. J Neurol 2008; 255: 1244–49

    CrossRefPubMed
16. 16.↵
    1. Lukas C,
    2. Hahn HK,
    3. Bellenberg B,
    4. et al

    . Sensitivity and reproducibility of a new fast 3D segmentation technique for clinical MR-based brain volumetry in multiple sclerosis. Neuroradiology 2004; 46: 906–15

    CrossRefPubMedWeb of Science
17. 17.↵
    1. Lukas C,
    2. Bellenberg B,
    3. Rexilius J,
    4. et al

    . A new sulcus-corrected approach for assessing cerebellar volume in spinocerebellar ataxia. European Congress of Radiology; ECR 2010, March 4–8, 2010, Vienna, Austria
18. 18.↵
    1. Luft AR,
    2. Skalej M,
    3. Welte D,
    4. et al

    . A new semiautomated, three-dimensional technique allowing precise quantification of total and regional cerebellar volume using MRI. Magn Reson Med 1998; 40: 143–51

    PubMedWeb of Science
19. 19.↵
    1. Bland M,
    2. Altman DG

    . Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307–10

    CrossRefPubMedWeb of Science
20. 20.↵
    1. Whitwell JL,
    2. Crum WR,
    3. Watt HC,
    4. et al

    . Normalization of cerebral volumes by use of intracranial volume: implications for longitudinal quantitative MR imaging. AJNR Am J Neuroradiol 2001; 22: 1483–89

    Abstract/FREE Full Text
21. 21.↵
    1. Blatter DD,
    2. Bigler ED,
    3. Gale SD,
    4. et al

    . Quantitative volumetric analysis of brain MR: normative database spanning 5 decades of life. AJNR Am J Neuroradiol 1995; 16: 241–51

    Abstract/FREE Full Text
22. 22.↵
    1. Pfefferbaum A,
    2. Mathalon DH,
    3. Sullivan EV,
    4. et al

    . A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch Neurol 1994; 51: 874–87

    CrossRefPubMedWeb of Science
23. 23.↵
    1. Luft AR,
    2. Skalej M,
    3. Schulz JB,
    4. et al

    . Patterns of age-related shrinkage in cerebellum and brainstem observed in vivo using three-dimensional MRI volumetry. Cereb Cortex 1999; 9: 712–21

    Abstract/FREE Full Text
24. 24.↵
    1. Burk K,
    2. Malzig U,
    3. Wolf S,
    4. et al

    . Comparison of three clinical rating scales in Friedreich ataxia (FRDA). Mov Disord 2009; 24: 1779–84

    CrossRefPubMed
25. 25.↵
    1. Schmitz-Hubsch T,
    2. du Montcel ST,
    3. Baliko L,
    4. et al

    . Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology 2006; 66:
26. 26.↵
    1. Schmitz-Hubsch T,
    2. Coudert M,
    3. Bauer P,
    4. et al

    . Spinocerebellar ataxia types 1, 2, 3, and 6: disease severity and nonataxia symptoms. Neurology 2008; 71: 982–89

    Abstract/FREE Full Text
27. 27.↵
    1. Richter S,
    2. Dimitrova A,
    3. Maschke M,
    4. et al

    . Degree of cerebellar ataxia correlates with three-dimensional MRI-based cerebellar volume in pure cerebellar degeneration. Eur Neurol 2005; 54: 23–27

    CrossRefPubMedWeb of Science
28. 28.↵
    1. Mitoma H,
    2. Hayashi R,
    3. Yanagisawa N,
    4. et al

    . Gait disturbances in patients with pontine medial tegmental lesions: clinical characteristics and gait analysis. Arch Neurol 2000; 57: 1048–57

    CrossRefPubMedWeb of Science
29. 29.↵
    1. Dietrichs E

    . Clinical manifestation of focal cerebellar disease as related to the organization of neural pathways. Acta Neurol Scand Suppl 2008; 188: 6–11

    PubMed
30. 30.↵
    1. Wessel K,
    2. Moschner C,
    3. Wandinger KP,
    4. et al

    . Oculomotor testing in the differential diagnosis of degenerative ataxic disorders. Arch Neurol 1998; 55: 949–56

    CrossRefPubMedWeb of Science
31. 31.↵
    1. Thier P,
    2. Dicke PW,
    3. Haas R,
    4. et al

    . The role of the oculomotor vermis in the control of saccadic eye movements. Ann N Y Acad Sci 2002; 978: 50–62

    CrossRefPubMedWeb of Science
32. 32.↵
    1. Lukas C,
    2. Schols L,
    3. Bellenberg B,
    4. et al

    . Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: a voxel-based morphometry study. Neurosci Lett 2006; 408: 230–35

    CrossRefPubMedWeb of Science