Investigation of Long-Term Reproducibility of Intrinsic Connectivity Network Mapping: A Resting-State fMRI Study

Within-subject test-retest reproducibility (A) and between-subject reproducibility (B) of the inter-regional correlation coefficients among the 116 regions of the whole brain. In this 116 × 116 square matrix, the x- and y-axes represent the 116 regions of the whole brain listed in On-line Table 1, and each matrix element indicates the link between a pair of listed brain regions. For example, the element marked by a red circle (ie, x = 31, y = 68) represents a link between the left anterior cingulate gyrus and the right precuneus. A, Each matrix element shows the level of within-subject reproducibility, measured by the ICC, of an inter-regional link. Note that >78% of the elements have outstanding or substantial within-subject test-retest reproducibility. B, Each element shows the level of between-subject reproducibility, measured by the COV. Less than 14% of the elements have acceptable between-subject reproducibility.