Article Figures & Data
Figures
- Fig 1.
CS system: 0 = absent collaterals >50% of an M2 territory; 1 = diminished collaterals >50% M2 territory; 2 = diminished collaterals <50% M2 territory; 3 = collaterals equal to contralateral side; 4 = increased collaterals.
- Fig 2.
There is progressive decrease in admission (A) DWI lesion volumes (P < .001) and (B) NIHSS (P < .001) as CS increases. Error bars represent 95% confidence intervals.
- Fig 3.
ROC curves for CS versus DWI volumes (A) >100 mL (AUC = 0.84, P < .001) and (B) >70 mL (AUC = 0.78, P < .001). Tables display test characteristics for various scores, including optimal operating points (*), and positive (PPV) and negative predictive values (NPV).
- Fig 4.
Scatterplot of DWI volumes versus CSs. Most CS = 0 patients have lesion volumes >70–100 mL (horizontal lines). There is great overlap between the other CS categories.
- Fig 5.
Distribution of mRS scores between patients with CS = 0 versus >0.
Tables
Collateral = 0 Collateral > 0 P value Number of patients 22 175 Age 71 ± 15 66 ± 17 0.25 Sex (female) 41% 36% 0.88 Side of stroke (left side) 59% 47% 0.44 Blood glucose (mg/dl) 149 ± 63 140 ± 50 0.56 Systolic blood pressure (mm Hg) 153 ± 125 150 ± 33 0.73 NIHSS score 21 (17–26) 15 (11–18) <0.001 DWI lesion volume (ml) 165.8 ± 19 32.7 ± 2.7 <0.001 3-month mRS 5 (3–6) 3 (1–5) 0.022 Dependent or deceased (mRS >2) 95.5% 64.0% 0.003 Treatment (IV and/or IA) 63.6% 67.2% 0.74 Note:—Results are expressed in mean ± SD, median (interquartile range), or percentages.
Collateral = 0 Collateral > 0 P value No treatment (# patients) 8 45 Good outcome (mRS ≤ 2) 0% 35.6% 0.044 Poor outcome (mRS > 2) 100% 64.4% IV treatment only (# patients) 13 30 Good outcome (mRS ≤ 2) 7.7% 50.0% 0.008 Poor outcome (mRS > 2) 92.3% 50.0% IA treatment ± IV (# patients) 1 75 Good outcome (mRS ≤ 2) 0% 30.7% 0.507 Poor outcome (mRS > 2) 100% 69.3%
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Malignant CTA Collateral Profile Is Highly Specific for Large Admission DWI Infarct Core and Poor Outcome in Acute Stroke
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