Atypical Diffusion-Restricted Lesion in 5-Fluorouracil Encephalopathy

Initial and follow-up brain MR images. Brain MR imaging shows high signal intensities in the bilateral basal ganglia, thalami, and parasagittal frontal cortex at symptom onset (A); improved status after 1 week (B); and no remarkable abnormalities after 3 months (C). There are axial diffusion-weighted images in the left column, an axial apparent diffusion coefficient map in the middle column, and axial FLAIR in the right column.