Article Figures & Data
Figures
- Fig. 1.
The NIHSS score on admission and at 3 months. A, NIHSS score of all patients (n = 31) excluding 4 patients who died. Median NIHSS scores were 12 on admission and 4 at 3 months (3 patients went from 9 to 2, three patients went from 8 to 1, and 2 patients went from 9 to 1). B, NIHSS scores of patients (n = 22) with favorable outcomes (mRS, 0–2) (3 patients went from 9 to 2, three patients went from 8 to 1, and 2 patients went from 9 to 1). Median NIHSS scores were 9 and 2. C, NIHSS scores of patients (n = 9) with unfavorable outcomes (mRS, 3–6). Median NIHSS scores were 17 and 9, respectively.
Tables
- Table 1:
Summary of patient demographics, preprocedural findings, periprocedural findings, and outcomes after 3 months
Patient Demographics No. (%) or Median (IQR) Range Age (yr) 65 (63–76) 51–84 Male 31 (88.6) – Previous medical history – – Diabetes mellitus 7 (20.0) – Hypertension 19 (54.3) – Hypercholesterolemia 10 (28.6) – Smoking 17 (48.6) – Cardiac disease 5 (14.3) – Prior stroke 6 (17.1) – Preprocedural findings Time to hospital (min)a 180 (125–210) 60–340 Time to IA therapy (min)a 270 (190–310) 140–435 NIHSS at admission 12 (8–17) 6–22 Modified Rankin scale 4 (3–4) 3–5 3 11 (31.4) – 4 21 (60.0) – 5 3 (8.6) – Right-sided occlusion 15 (42.9) – Tandem occlusion site – – M1 25 (71.4) – M2 5 (14.3) – Distal ICA thrombus 5 (14.3) – Received IV rtPA 8 (22.9) – Periprocedural findings Procedure duration (min) 90 (68–120) 40–180 Urokinase dose (× 104 U) 10 (10–30) 10–50 TICI grade – – IIa 9 (25.7) – IIb 7 (20.0) – III 19 (54.3) – Complications 2 (5.7) – Symptomatic hemorrhage 1 (2.9) – Brain swelling 1 (2.9) – Follow-up evaluation at 3 months NIHSSb 4 (2–7) 1–17 Modified Rankin Scale 2 (1–3) 0–6 0 3 (8.6) – 1 11 (31.4) – 2 8 (22.9) – 3 5 (14.3) – 4 4 (11.4) – 5 0 (0.0) – 6 4 (11.4) – Favorable outcome 22 (62.9) – Mortality 4 (11.4) – - Table 2:
Comparisons between patients who had favorable and unfavorable outcomes 3 months after recanalization
Patient Demographics % or Median (IQR) P Favorable Outcome (n = 22) Unfavorable Outcome (n = 13) Age (yr) 64 (61–69) 73 (65–77) .040 Male 90.9 84.6 .618 Medical history – – – Diabetes mellitus 22.7 15.4 .689 Hypertension 54.5 53.8 1.000 Hypercholesterolemia 27.3 30.8 1.000 Smoking 45.5 53.8 .733 Cardiac disease 18.2 7.7 .630 Prior stroke 9.1 30.8 .166 Preprocedural findings Time to hospital (min)a 180 (138–208) 180 (100–210) .851 Time to IA therapy (min)a 255 (200–279) 280 (180–360) .669 NIHSS score at admission 9 (8–14) 17 (13–18) .003 Modified Rankin Scale score 4 (3–4) 4 (4–4) .005 3 45.5 7.7 .027 4 54.5 69.2 .486 5 0.0 23.1 .044 Right-sided occlusion 27.3 69.2 .032 Tandem occlusion site – – .247b M1 63.6 84.6 .259 M2 22.7 0.0 .134 Distal ICA thrombus 13.6 15.4 1.000 Received IV rtPA 18.2 30.8 .433 Periprocedural findings Procedure duration (min) 90 (66–128) 95 (70–110) .891 Urokinase dose (×104 U) 10 (10–30) 20 (10–20) .648 TICI grade – – .006c IIa 9.1 53.8 .006 IIb 22.7 15.4 .689 III 68.2 30.8 .043 Complications 0.0 15.4 .144 Symptomatic hemorrhage 0.0 7.7 .371 Brain swelling 0.0 7.7 .371 Follow-up evaluation at 3 months NIHSS scored 2 (2–4) 9 (6–16) <.001 - Table 3:
Multivariate logistic regression results for independent predictors of an unfavorable outcome after 3 monthsa
Predictor Univariate Multivariate OR (95% CI) P OR (95% CI) P NIHSS score at admission (per unit change) 1.4 (1.1–1.7) .003 1.8 (1.1–3.1) .022 TICI grade IIa 11.7 (1.9–71.8) .006 458 (3.4–627) .015 Right-sided occlusion 6.0 (1.3–27.0) .032 31.9 (1.1–9.1) .043 Note:—OR indicates odds ratio; CI, confidence interval.
↵a Variables were chosen by backward selection. Univariate columns show results for each variable fit separately. Multivariate columns show results from a single model fitting all variables simultaneously.
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