Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Research ArticleHead & Neck

Incidental Thyroid Nodules on CT: Evaluation of 2 Risk-Categorization Methods for Work-Up of Nodules

X.V. Nguyen, K. Roy Choudhury, J.D. Eastwood, G.H. Lyman, R.M. Esclamado, J.D. Werner and J.K. Hoang
American Journal of Neuroradiology September 2013, 34 (9) 1812-1817; DOI: https://doi.org/10.3174/ajnr.A3487
X.V. Nguyen
aFrom the Department of Radiology (X.N., K.R.C., J.D.E., J.D.W., J.K.H.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K. Roy Choudhury
aFrom the Department of Radiology (X.N., K.R.C., J.D.E., J.D.W., J.K.H.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.D. Eastwood
aFrom the Department of Radiology (X.N., K.R.C., J.D.E., J.D.W., J.K.H.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G.H. Lyman
bDivision of Otolaryngology, Head and Neck Surgery (G.H.L.), Department of Surgery
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R.M. Esclamado
cDivision of Oncology (R.M.E.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.D. Werner
aFrom the Department of Radiology (X.N., K.R.C., J.D.E., J.D.W., J.K.H.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.K. Hoang
aFrom the Department of Radiology (X.N., K.R.C., J.D.E., J.D.W., J.K.H.)
dDepartment of Radiation Oncology (J.K.H.), Department of Medicine; Duke University Medical Center, Durham, North Carolina.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Cause-specific survival curves as a function of tumor size for thyroid cancers in the SEER data base. This represents method A of risk categorization.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Cause-specific survival curves of thyroid cancers in SEER stratified by the 3-tiered system (method B).

Tables

  • Figures
    • View popup
    Table 1:

    Survival of patients with thyroid carcinoma by patient demographics and tumor characteristics

    Percentage Total10-Year Relative Survival (%)95% CI10-Year Thyroid Cancer–Specific Survival (%)95% CI
    Total100%97.497.0–97.795.795.5–95.9
    Sex
        Male23%93.892.9–94.792.091.4–92.5
        Female77%98.498.0–98.696.896.6–97.0
    Age (yr)
        0–192.2%99.198.3–99.599.398.7–99.6
        20–3421%99.398.9–99.599.799.5–99.8
        35–4936%99.398.9–99.598.998.7–99.0
        50–6427%96.295.3–96.994.694.1–95.1
        ≥6515%90.388.1–92.181.079.9–82.0
    SEER summary stage
        Localized or unstaged61%99.999.8–99.999.098.9–99.1
        Regional35%95.695.0–96.294.494.0–94.8
        Distant4.1%56.153.5–58.558.256.0–60.4
    Tumor size (mm)
        <512%99.999.7–99.999.499.0–99.6
        5–1014%99.899.6–99.998.998.6–99.2
        10–1415%99.899.5–99.999.098.7–99.2
        15–1913%99.899.5–99.998.397.9–98.6
        20–2920%99.498.3–99.897.096.7–97.4
        30–3911%96.695.5–97.495.294.6–95.7
        ≥4014%84.082.7–85.283.382.4–84.2
    • View popup
    Table 2:

    Survival in patients with thyroid malignancy in the SEER data base using risk-categorization methods of size cutoff (method A) and the 3-tiered system (method B)a

    Percentage Total10-Year Relative Survival (%)95% CI10-Year Thyroid Cancer-Specific Survival (%)95% CI
    Method A (size cutoff)
        ≥10 mm74%96.496.0–96.794.794.4–94.9
        <10 mm26%99.899.7–99.999.198.9–99.3
        ≥15 mm59%95.494.9–95.893.793.4–94.0
        <15 mm41%99.899.8–99.999.198.9–99.2
        ≥20 mm46%94.193.5–94.692.492.0–92.7
        <20 mm54%99.999.8–99.998.998.7–99.0
    Method B (3-tiered risk categories)
        Categories 1, 2, and 374%96.095.6–96.394.694.3–94.8
        Category 139%91.590.9–92.190.790.3–91.1
        Category 213%99.799.2–99.999.999.7–99.9
        Category 323%99.899.7–99.998.097.7–98.3
        Not categorized26%99.999.8–99.999.599.3–99.7
    • ↵a Nodules smaller than the size cutoff and in the “not categorized” group for method B would represent nodules that would not receive work-up if the methods were applied.

    • View popup
    Table 3:

    Comparison of capture rates of incidental thyroid nodules by methods A and Ba

    Categorization MethodPatientsTotal
    Method A (size cutoff)
        ≥10 mm5743%
        <10 mm7657%
        ≥15 mm2217%
        <15 mm11183%
        ≥20 mm129%
        <20 mm12191%
    Method B (3-tiered system)
        Category 1, 2, or 33123%
        Category 122%
        Category 297%
        Category 32015%
        Not categorized10277%
    Total133
    • ↵a Incidental thyroid nodules from retrospective CT review were stratified by size cutoff (method A) and the 3-tiered system (method B). The nodules smaller than the size cutoff and in the “not categorized” group for method B would represent nodules that would not receive work-up if the methods were applied.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 34 (9)
American Journal of Neuroradiology
Vol. 34, Issue 9
1 Sep 2013
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Incidental Thyroid Nodules on CT: Evaluation of 2 Risk-Categorization Methods for Work-Up of Nodules
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Incidental Thyroid Nodules on CT: Evaluation of 2 Risk-Categorization Methods for Work-Up of Nodules
X.V. Nguyen, K. Roy Choudhury, J.D. Eastwood, G.H. Lyman, R.M. Esclamado, J.D. Werner, J.K. Hoang
American Journal of Neuroradiology Sep 2013, 34 (9) 1812-1817; DOI: 10.3174/ajnr.A3487

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Incidental Thyroid Nodules on CT: Evaluation of 2 Risk-Categorization Methods for Work-Up of Nodules
X.V. Nguyen, K. Roy Choudhury, J.D. Eastwood, G.H. Lyman, R.M. Esclamado, J.D. Werner, J.K. Hoang
American Journal of Neuroradiology Sep 2013, 34 (9) 1812-1817; DOI: 10.3174/ajnr.A3487
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Benign and Malignant Thyroid Incidentalomas Are Rare in Routine Clinical Practice: A Review of 97,908 Imaging Studies
  • Radiology Reports for Incidental Thyroid Nodules on CT and MRI: High Variability across Subspecialties
  • Imaging-Detected Incidental Thyroid Nodules that Undergo Surgery: A Single-Center Experience Over 1 Year
  • High Variability in Radiologists' Reporting Practices for Incidental Thyroid Nodules Detected on CT and MRI
  • An Exponential Growth in Incidence of Thyroid Cancer: Trends and Impact of CT Imaging
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Phosphaturic Mesenchymal Tumor
  • Microstructural Visual Pathway White Matter Alterations in Primary Open-Angle Glaucoma: A Neurite Orientation Dispersion and Density Imaging Study
  • Iodine Maps from Dual-Energy CT to Predict Extrathyroidal Extension and Recurrence in Papillary Thyroid Cancer Based on a Radiomics Approach
Show more HEAD & NECK

Similar Articles

Advertisement

News and Updates

  • Lucien Levy Best Research Article Award
  • Thanks to our 2021 Distinguished Reviewers
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2022 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire