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Research ArticleBrain

Susceptibility-Weighted MR Imaging: A Better Technique in the Detection of Capillary Telangiectasia Compared with T2* Gradient-Echo

U.S. Chaudhry, D.E. De Bruin and B.A. Policeni
American Journal of Neuroradiology December 2014, 35 (12) 2302-2305; DOI: https://doi.org/10.3174/ajnr.A4082
U.S. Chaudhry
aFrom the Department of Radiology (U.S.C., D.E.D., B.A.P.)
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D.E. De Bruin
aFrom the Department of Radiology (U.S.C., D.E.D., B.A.P.)
bSection of Neuroradiology (D.E.D., B.A.P.), University of Iowa Hospitals and Clinics, Iowa City, Iowa.
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B.A. Policeni
aFrom the Department of Radiology (U.S.C., D.E.D., B.A.P.)
bSection of Neuroradiology (D.E.D., B.A.P.), University of Iowa Hospitals and Clinics, Iowa City, Iowa.
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Abstract

BACKGROUND AND PURPOSE: Enhancing lesions on brain MR imaging can present a diagnostic quandary as both benign lesions such as brain capillary telangiectasia and pathologic lesions such as demyelination may appear similar. Stagnation of blood in low-flow venous channels of brain capillary telangiectasias results in susceptibility effect secondary to the increased local deoxyhemoglobin. Both T2* gradient-echo imaging and SWI were demonstrated as valuable in the diagnosis of brain capillary telangiectasia. Because SWI is more sensitive to susceptibility changes than gradient-echo, we aim to demonstrate increased diagnostic value of SWI compared with gradient-echo in making the diagnosis of brain capillary telangiectasia.

MATERIALS AND METHODS: We retrospectively reviewed the MR images of 17 patients with a presumed diagnosis of brain capillary telangiectasia and who were examined from June 2010 to September 2012. All patients underwent MR imaging at 1.5T with T1, T2, FLAIR, gradient-echo, SWI, and gadolinium-enhanced T1 sequences. Lesions were evaluated for the presence or absence of signal abnormality on each particular sequence.

RESULTS: All 17 brain capillary telangiectasias demonstrated distinct signal-intensity loss on SWI compared with 7 of 17 (41%) who showed signal-intensity loss on gradient-echo. The increased frequency of detection using SWI versus gradient-echo is statistically significant (z = 2.85, P < .01; χ2 = 8.10, P < .01). Six of the lesions showed signal-intensity changes on T1 and/or T2 whereas the remaining lesions were isointense to normal brain.

CONCLUSIONS: Brain capillary telangiectasias are more conspicuous on SWI than gradient-echo imaging and other precontrast MR imaging. SWI is a valuable tool in diagnosing these benign lesions and should serve to increase diagnostic confidence.

ABBREVIATIONS:

BCT
brain capillary telangiectasia
GRE
gradient-echo
  • © 2014 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 35 (12)
American Journal of Neuroradiology
Vol. 35, Issue 12
1 Dec 2014
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Susceptibility-Weighted MR Imaging: A Better Technique in the Detection of Capillary Telangiectasia Compared with T2* Gradient-Echo
U.S. Chaudhry, D.E. De Bruin, B.A. Policeni
American Journal of Neuroradiology Dec 2014, 35 (12) 2302-2305; DOI: 10.3174/ajnr.A4082

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Susceptibility-Weighted MR Imaging: A Better Technique in the Detection of Capillary Telangiectasia Compared with T2* Gradient-Echo
U.S. Chaudhry, D.E. De Bruin, B.A. Policeni
American Journal of Neuroradiology Dec 2014, 35 (12) 2302-2305; DOI: 10.3174/ajnr.A4082
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