Visual-Statistical Interpretation of 18F-FDG-PET Images for Characteristic Alzheimer Patterns in a Multicenter Study: Inter-Rater Concordance and Relationship to Automated Quantitative Evaluation

^aFrom the Division of Molecular Imaging (T.Y., Y.I., T.N., M. Senda), Institute of Biomedical Research and Innovation, Kobe, Japan
^bDepartment of Radiology (Kazunari Ishii), Kinki University Faculty of Medicine, Osakasayama, Japan
^cPositron Medical Center (Kenji Ishii), Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
^dDepartment of Brain Science and Molecular Imaging (T.K., K. Ito), National Center for Geriatrics and Gerontology, Obu, Japan
^eDavid Geffen School of Medicine (D.H.S.S.), University of California, Los Angeles, Los Angeles, California
^fDepartment of Psychiatry (T.A.), University of Tsukuba, Tsukuba, Japan
^gDepartment of Geriatrics and Gerontology (H.A.), Tohoku University, Sendai, Japan
^hInstitute of Brain and Blood Vessels (M. Sugishita), Isezaki, Japan
ⁱDepartment of Neuropathology and Neuroscience (T.I.), University of Tokyo, Tokyo, Japan
^jResearch Association for Biotechnology (Y.I., T.N.), Tokyo, Japan
^kJ-ADNI Core (T.Y., Y.I., T.N., Kazunari Ishii, Kenji Ishii, T.K., Kengo Ito, M.S., T.A., H.A., M.S., T.I.).

Please address correspondence to Tomohiko Yamane, MD, PhD, Division of Molecular Imaging, Institute of Biomedical Research and Innovation, 2–2, Minatojima-minamimachi, Chuo-ku, Kobe, 650-0047, Japan; e-mail address: yamane{at}fbri.org