Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editorial Board
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editorial Board
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Research ArticleBrain

Diffusion Measures Indicate Fight Exposure–Related Damage to Cerebral White Matter in Boxers and Mixed Martial Arts Fighters

W. Shin, S.Y. Mahmoud, K. Sakaie, S.J. Banks, M.J. Lowe, M. Phillips, M.T. Modic and C. Bernick
American Journal of Neuroradiology February 2014, 35 (2) 285-290; DOI: https://doi.org/10.3174/ajnr.A3676
W. Shin
aFrom the Imaging Institute (W.S., S.Y.M., K.S., M.J.L., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.Y. Mahmoud
aFrom the Imaging Institute (W.S., S.Y.M., K.S., M.J.L., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K. Sakaie
aFrom the Imaging Institute (W.S., S.Y.M., K.S., M.J.L., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.J. Banks
cLou Ruvo Center for Brain Health (S.J.B., M.T.M.), Cleveland Clinic, Las Vegas, Nevada.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M.J. Lowe
aFrom the Imaging Institute (W.S., S.Y.M., K.S., M.J.L., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Phillips
aFrom the Imaging Institute (W.S., S.Y.M., K.S., M.J.L., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M.T. Modic
cLou Ruvo Center for Brain Health (S.J.B., M.T.M.), Cleveland Clinic, Las Vegas, Nevada.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. Bernick
bNeurological Institute (C.B.), Cleveland Clinic, Cleveland, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Bledsoe GH,
    2. Li G,
    3. Levy F
    . Injury risk in professional boxing. South Med J 2005;98:994–98
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Blonstein JL
    . Letter: Traumatic encephalopathy in a young boxer. Lancet 1974;2:1213
    PubMed
  3. 3.↵
    1. Guterman A,
    2. Smith RW
    . Neurological sequelae of boxing. Sports Med 1987;4:194–210
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Handratta V,
    2. Hsu E,
    3. Vento J,
    4. et al
    . Neuroimaging findings and brain-behavioral correlates in a former boxer with chronic traumatic brain injury. Neurocase 2010;16:125–34
    CrossRefPubMed
  5. 5.↵
    1. Harvey PK,
    2. Davis JN
    . Traumatic encephalopathy in a young boxer. Lancet 1974;2:928–29
    PubMedWeb of Science
  6. 6.↵
    1. Saing T,
    2. Dick MC,
    3. Nelson PT,
    4. et al
    . Frontal cortex neuropathology in dementia pugilistica. J Neurotrauma 2012;29:1054–70
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Zhang L,
    2. Heier LA,
    3. Zimmerman RD,
    4. et al
    . Diffusion anisotropy changes in the brains of professional boxers. AJNR Am J Neuroradiol 2006;27:2000–04
    Abstract/FREE Full Text
  8. 8.↵
    1. Zhang L,
    2. Ravdin LD,
    3. Relkin N,
    4. et al
    . Increased diffusion in the brain of professional boxers: a preclinical sign of traumatic brain injury? AJNR Am J Neuroradiol 2003;24:52–57
    Abstract/FREE Full Text
  9. 9.↵
    1. McKee AC,
    2. Cantu RC,
    3. Nowinski CJ,
    4. et al
    . Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol 2009;68:709–35
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Mendez MF
    . The neuropsychiatric aspects of boxing. Int J Psychiatr Med 1995;25:249–62
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Yuan W,
    2. Holland SK,
    3. Schmithorst VJ,
    4. et al
    . Diffusion tensor MR imaging reveals persistent white matter alteration after traumatic brain injury experienced during early childhood. AJNR Am J Neuroradiol 2007;28:1919–25
    Abstract/FREE Full Text
  12. 12.↵
    1. Wu TC,
    2. Wilde EA,
    3. Bigler ED,
    4. et al
    . Longitudinal changes in the corpus callosum following pediatric traumatic brain injury. Dev Neurosci 2010;32:361–73
    PubMed
  13. 13.↵
    1. Sidaros A,
    2. Engberg AW,
    3. Sidaros K,
    4. et al
    . Diffusion tensor imaging during recovery from severe traumatic brain injury and relation to clinical outcome: a longitudinal study. Brain 2008;131:559–72
    Abstract/FREE Full Text
  14. 14.↵
    1. Rutgers DR,
    2. Toulgoat F,
    3. Cazejust J,
    4. et al
    . White matter abnormalities in mild traumatic brain injury: a diffusion tensor imaging study. AJNR Am J Neuroradiol 2008;29:514–19
    Abstract/FREE Full Text
  15. 15.↵
    1. Matthews PM
    . Brain imaging of multiple sclerosis: the next 10 years. Neuroimaging Clin North Am 2009;19:101–12
    CrossRef
  16. 16.↵
    1. Xu J,
    2. Rasmussen IA,
    3. Lagopoulos J,
    4. et al
    . Diffuse axonal injury in severe traumatic brain injury visualized using high-resolution diffusion tensor imaging. J Neurotrauma 2007;24:753–65
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Inglese M,
    2. Makani S,
    3. Johnson G,
    4. et al
    . Diffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study. J Neurosurg 2005;103:298–303
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Shanmuganathan K,
    2. Gullapalli RP,
    3. Mirvis SE,
    4. et al
    . Whole-brain apparent diffusion coefficient in traumatic brain injury: correlation with Glasgow Coma Scale score. AJNR Am J Neuroradiol 2004;25:539–44
    Abstract/FREE Full Text
  19. 19.↵
    1. Chappell MH,
    2. Ulug AM,
    3. Zhang L,
    4. et al
    . Distribution of microstructural damage in the brains of professional boxers: a diffusion MRI study. J Magn Reson Imaging 2006;24:537–42
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Jezzard P,
    2. Balaban RS
    . Correction for geometric distortion in echo planar images from B0 field variations. Magn Reson Med 1995;34:65–73
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Sakaie KE,
    2. Shin W,
    3. Curtin KR,
    4. et al
    . Method for improving the accuracy of quantitative cerebral perfusion imaging. J Magn Reson Imaging 2005;21:512–19
    CrossRefPubMed
  22. 22.↵
    1. Basser PJ,
    2. Mattiello J,
    3. LeBihan D
    . MR diffusion tensor spectroscopy and imaging. Biophys J 1994;66:259–67
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. Basser PJ,
    2. Pierpaoli C
    . Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson 1996;111:209–19
    CrossRefWeb of Science
  24. 24.↵
    1. Jenkinson M,
    2. Smith S
    . A global optimisation method for robust affine registration of brain images. Med Image Analysis 2001;5:143–56
    CrossRefWeb of Science
  25. 25.↵
    1. Rutgers DR,
    2. Fillard P,
    3. Paradot G,
    4. et al
    . Diffusion tensor imaging characteristics of the corpus callosum in mild, moderate, and severe traumatic brain injury. AJNR Am J Neuroradiol 2008;29:1730–35
    Abstract/FREE Full Text
  26. 26.↵
    1. Schaefer PW,
    2. Huisman TA,
    3. Sorensen AG,
    4. et al
    . Diffusion-weighted MR imaging in closed head injury: high correlation with initial Glasgow Coma Scale score and score on modified Rankin Scale at discharge. Radiology 2004;233:58–66
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Wilde EA,
    2. Chu Z,
    3. Bigler ED,
    4. et al
    . Diffusion tensor imaging in the corpus callosum in children after moderate to severe traumatic brain injury. J Neurotrauma 2006;23:1412–26
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Farbota KD,
    2. Bendlin BB,
    3. Alexander AL,
    4. et al
    . Longitudinal diffusion tensor imaging and neuropsychological correlates in traumatic brain injury patients. Front Hum Neurosci 2012;6:160
    PubMed
  29. 29.↵
    1. Wang JY,
    2. Bakhadirov K,
    3. Abdi H,
    4. et al
    . Longitudinal changes of structural connectivity in traumatic axonal injury. Neurology 2011;77:818–26
    CrossRef
  30. 30.↵
    1. Kraus MF,
    2. Susmaras T,
    3. Caughlin BP,
    4. et al
    . White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain 2007;130:2508–19
    Abstract/FREE Full Text
  31. 31.↵
    1. Cubon VA,
    2. Putukian M,
    3. Boyer C,
    4. et al
    . A diffusion tensor imaging study on the white matter skeleton in individuals with sports-related concussion. J Neurotrauma 2011;28:189–201
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Zhang K,
    2. Johnson B,
    3. Pennell D,
    4. et al
    . Are functional deficits in concussed individuals consistent with white matter structural alterations: combined FMRI & DTI study. Exp Brain Res Experimentelle Hirnforschung 2010;204:57–70
    CrossRef
  33. 33.↵
    1. Bazarian JJ,
    2. Zhong J,
    3. Blyth B,
    4. et al
    . Diffusion tensor imaging detects clinically important axonal damage after mild traumatic brain injury: a pilot study. J Neurotrauma 2007;24:1447–59
    CrossRefPubMedWeb of Science
  34. 34.↵
    1. Wilde EA,
    2. McCauley SR,
    3. Hunter JV,
    4. et al
    . Diffusion tensor imaging of acute mild traumatic brain injury in adolescents. Neurology 2008;70:948–55
    CrossRef
  35. 35.↵
    1. McAllister TW,
    2. Ford JC,
    3. Ji S,
    4. et al
    . Maximum principal strain and strain rate associated with concussion diagnosis correlates with changes in corpus callosum white matter indices. Ann Biomed Eng 2012;40:127–40
    CrossRefPubMed
  36. 36.↵
    1. Mayer AR,
    2. Ling J,
    3. Mannell MV,
    4. et al
    . A prospective diffusion tensor imaging study in mild traumatic brain injury. Neurology 2010;74:643–50
    CrossRef
  37. 37.↵
    1. Ling JM,
    2. Pena A,
    3. Yeo RA,
    4. et al
    . Biomarkers of increased diffusion anisotropy in semi-acute mild traumatic brain injury: a longitudinal perspective. Brain 2012;135:1281–92
    Abstract/FREE Full Text
  38. 38.↵
    1. Wilde EA,
    2. McCauley SR,
    3. Barnes A,
    4. et al
    . Serial measurement of memory and diffusion tensor imaging changes within the first week following uncomplicated mild traumatic brain injury. Brain Imaging Behav 2012;6:319–28
    CrossRefPubMedWeb of Science
  39. 39.↵
    1. Chepuri NB,
    2. Yen YF,
    3. Burdette JH,
    4. et al
    . Diffusion anisotropy in the corpus callosum. AJNR Am J Neuroradiol 2002;23:803–08
    Abstract/FREE Full Text
  40. 40.↵
    1. Pfefferbaum A,
    2. Sullivan EV
    . Increased brain white matter diffusivity in normal adult aging: relationship to anisotropy and partial voluming. Magn Reson Med 2003;49:953–61
    CrossRefPubMedWeb of Science
  41. 41.↵
    1. Ardekani S,
    2. Kumar A,
    3. Bartzokis G,
    4. et al
    . Exploratory voxel-based analysis of diffusion indices and hemispheric asymmetry in normal aging. Magn Reson Imaging 2007;25:154–67
    CrossRefPubMedWeb of Science
  42. 42.↵
    1. Giorgio A,
    2. Santelli L,
    3. Tomassini V,
    4. et al
    . Age-related changes in grey and white matter structure throughout adulthood. NeuroImage 2010;51:943–51
    CrossRefPubMedWeb of Science
  43. 43.↵
    1. Mabbott DJ,
    2. Noseworthy MD,
    3. Bouffet E,
    4. et al
    . Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: correlation with IQ. Neuro-Oncology 2006;8:244–52
    Abstract/FREE Full Text
  44. 44.↵
    1. Yu C,
    2. Li J,
    3. Liu Y,
    4. et al
    . White matter tract integrity and intelligence in patients with mental retardation and healthy adults. NeuroImage 2008;40:1533–41
    CrossRefPubMed
  45. 45.↵
    1. Xu J,
    2. Li Y,
    3. Lin H,
    4. et al
    . Body mass index correlates negatively with white matter integrity in the fornix and corpus callosum: a diffusion tensor imaging study. Hum Brain Mapp 2013;34:1044–52
    CrossRefPubMed
  46. 46.↵
    1. McCrea M,
    2. Hammeke T,
    3. Olsen G,
    4. et al
    . Unreported concussion in high school football players: implications for prevention. Clin J Sport Med 2004;14:13–17
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 35 (2)
American Journal of Neuroradiology
Vol. 35, Issue 2
1 Feb 2014
  • Complete Issue (PDF)
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Diffusion Measures Indicate Fight Exposure–Related Damage to Cerebral White Matter in Boxers and Mixed Martial Arts Fighters
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
Citation Tools
Diffusion Measures Indicate Fight Exposure–Related Damage to Cerebral White Matter in Boxers and Mixed Martial Arts Fighters
W. Shin, S.Y. Mahmoud, K. Sakaie, S.J. Banks, M.J. Lowe, M. Phillips, M.T. Modic, C. Bernick
American Journal of Neuroradiology Feb 2014, 35 (2) 285-290; DOI: 10.3174/ajnr.A3676

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Diffusion Measures Indicate Fight Exposure–Related Damage to Cerebral White Matter in Boxers and Mixed Martial Arts Fighters
W. Shin, S.Y. Mahmoud, K. Sakaie, S.J. Banks, M.J. Lowe, M. Phillips, M.T. Modic, C. Bernick
American Journal of Neuroradiology Feb 2014, 35 (2) 285-290; DOI: 10.3174/ajnr.A3676
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • Scopus
  • PubMed
  • Google Scholar

Cited By...

  • Concussion management in combat sports: consensus statement from the Association of Ringside Physicians
  • Prevalence of Traumatic Findings on Routine MRI in a Large Cohort of Professional Fighters
  • Scopus (34)
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • SWI or T2*: Which MRI Sequence to Use in the Detection of Cerebral Microbleeds? The Karolinska Imaging Dementia Study
  • Progression of Microstructural Damage in Spinocerebellar Ataxia Type 2: A Longitudinal DTI Study
  • Statin Therapy Does Not Affect the Radiographic and Clinical Profile of Patients with TIA and Minor Stroke
Show more BRAIN

Similar Articles

Advertisement

News and Updates

  • Thanks to our 2018 Reviewers
  • 2017 Lucien Levy Best Research Article Award
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat
  • Free CME for Literature Searches

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2019 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire