Article Figures & Data
Figures
- Fig 1.
Ninety-day modified Rankin Scale scores. The distribution of 90-day modified Rankin Scale scores among patients according to the SPAN-100 index. The lines indicate the mRS category (mRS 0–2 and mRS 5–6) between SPAN-100 groups. P value refers to the significance level of the χ2 test for proportion comparison.
Tables
Outcome Entire Cohort (N = 202) SPAN-100-Positive (n = 15) SPAN-100-Negative (n = 181) Median time from stroke onset to groin puncture (min) (range) 238 (72–714) 280 (140–450) 235 (72–714) Successful recanalization (after rescue therapy) as per core laba 88% (171/194) 93% (14/15) 87% (151/173) Median time from stroke onset to TICI 2b or 3 (or final DSA run) (min) (range) 282 (100–800) 322 (188–483) 282 (100–800) Stroke onset to successful revascularization categories 0–4.5 hr 46% (92/201) 20% (3/15) 47% (84/180) 4.5–8 hr 50% (101/201) 73% (11/15) 49% (89/180) ≥8 hr 4% (8/201) 7% (1/15) 4% (7/180) Device- or procedure-related serious adverse events 7% (15/202) 7% (1/15) 8% (14/181) Any intracranial hemorrhage 19% (38/202) 27% (4/15) 19% (34/181) Symptomatic intracranial hemorrhage 1% (3/202) 0% (0/15) 2% (3/181) 90-Day clinical outcomes Death from any cause 7% (14/202) 27% (4/15) 6% (10/181) Good functional recovery (modified Rankin Scale score 0–2) 58% (117/202) 27% (4/15) 61% (110/181) ↵a Core laboratory missed the primary end point data of 8 subjects.
- Table 2:
Univariable and multivariable logistic regressions of favorable clinical outcome (mRS ≤2)
Variable Univariable Multivariable Odds Ratio 95% CI P Value Odds Ratio 95% CI P Value SPAN-100-positive 0.23 (0.07–0.77) .02 0.25 (0.07–0.91) .04 Baseline ASPECTS 1.32 (1.10–1.59) .003 1.28 (1.04–1.58) .02 Time from stroke onset to TICI 2b or 3 (or final DSA run, hr) 0.70 (0.58–0.84) <.001 0.68 (0.55–0.84) <.001 Primary end point success 1.81 (0.82–3.96) .14 1.73 (0.74–4.03) .21 IV-tPA administered (vs contraindicated or bridging) 1.05 (0.59–1.87) .87 1.27 (0.64–2.52) .49
Impact of Age and Baseline NIHSS Scores on Clinical Outcomes in the Mechanical Thrombectomy Using Solitaire FR in Acute Ischemic Stroke Study
