Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Research ArticleInterventional

The FRED Flow-Diverter Stent for Intracranial Aneurysms: Clinical Study to Assess Safety and Efficacy

M.A. Möhlenbruch, C. Herweh, L. Jestaedt, S. Stampfl, S. Schönenberger, P.A. Ringleb, M. Bendszus and M. Pham
American Journal of Neuroradiology June 2015, 36 (6) 1155-1161; DOI: https://doi.org/10.3174/ajnr.A4251
M.A. Möhlenbruch
aFrom the Departments of Neuroradiology (M.A.M., C.H., L.J., S. Stampfl, M.B., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. Herweh
aFrom the Departments of Neuroradiology (M.A.M., C.H., L.J., S. Stampfl, M.B., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Jestaedt
aFrom the Departments of Neuroradiology (M.A.M., C.H., L.J., S. Stampfl, M.B., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Stampfl
aFrom the Departments of Neuroradiology (M.A.M., C.H., L.J., S. Stampfl, M.B., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Schönenberger
bNeurology (S. Schönenberger, P.A.R.); University of Heidelberg Medical Center, Heidelberg, Germany.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.A. Ringleb
bNeurology (S. Schönenberger, P.A.R.); University of Heidelberg Medical Center, Heidelberg, Germany.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Bendszus
aFrom the Departments of Neuroradiology (M.A.M., C.H., L.J., S. Stampfl, M.B., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Pham
aFrom the Departments of Neuroradiology (M.A.M., C.H., L.J., S. Stampfl, M.B., M.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Patient 1 with a 4.4-mm residual aneurysm of the initial posterior inferior cerebellar artery segment close to its origin from the V4 segment of the left vertebral artery (solid white arrow, A). After recoiling, we implanted a FRED 3.5 × 13 mm to cover the orifice of the posterior inferior cerebellar artery origin (B). The flow-diverting working zone (inner stent) is centrally positioned over the posterior inferior cerebellar artery origin (solid white bracket marked with 1 asterisk, C). The outer stent, which provides stable vessel anchorage symmetrically, overlaps the proximal and distal edge of the inner flow-diverting stent. Its distal flared ends are marked with solid white brackets and 2 asterisks (C). At 3-month follow-up, complete occlusion of the residual aneurysm was observed, with no residual inflow (D), which was also verified on different projections and 3D DSA. At the base of the coil basket, the overprojection of a proximal posterior inferior cerebellar artery loop (dashed white arrow, D) simulates residual aneurysm filling, but contrast washes out rapidly at this position after the arterial phase (not shown). Complete occlusion was also confirmed by unenhanced and enhanced TOF-MRA at 3 and 6 months.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Patient 7 with a 6.5-mm supraclinoid ICA aneurysm (A). In this case, a FRED 4.5 × 25 mm could be placed to cover the aneurysm neck with the inner stent mesh having the flow-diverting effect (dashed white line). Complete wall apposition can be appreciated along the entire carotid siphon (B). The outer stent ensuring stable vessel wall anchorage overlaps the inner flow-diverting stent over 3.5 mm at its proximal and distal ends (double-headed white arrows, B). At its termination, 4 radiopaque tips mark the flared ends. At 3-month follow-up, complete occlusion of the aneurysm could be confirmed on DSA (C) with no residual inflow, which was also confirmed by MR imaging at that time and remained stable at 6-month follow-up.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 36 (6)
American Journal of Neuroradiology
Vol. 36, Issue 6
1 Jun 2015
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The FRED Flow-Diverter Stent for Intracranial Aneurysms: Clinical Study to Assess Safety and Efficacy
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
The FRED Flow-Diverter Stent for Intracranial Aneurysms: Clinical Study to Assess Safety and Efficacy
M.A. Möhlenbruch, C. Herweh, L. Jestaedt, S. Stampfl, S. Schönenberger, P.A. Ringleb, M. Bendszus, M. Pham
American Journal of Neuroradiology Jun 2015, 36 (6) 1155-1161; DOI: 10.3174/ajnr.A4251

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The FRED Flow-Diverter Stent for Intracranial Aneurysms: Clinical Study to Assess Safety and Efficacy
M.A. Möhlenbruch, C. Herweh, L. Jestaedt, S. Stampfl, S. Schönenberger, P.A. Ringleb, M. Bendszus, M. Pham
American Journal of Neuroradiology Jun 2015, 36 (6) 1155-1161; DOI: 10.3174/ajnr.A4251
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Safety and efficacy results of the Flow Redirection Endoluminal Device (FRED) stent system in the treatment of intracranial aneurysms: US pivotal trial
  • Treatment of Ruptured Blister-Like Aneurysms with the FRED Flow Diverter: A Multicenter Experience
  • Incomplete stent apposition of low-profile visualized intraluminal support stents in the treatment of cerebral aneurysms
  • Efficacy and safety of the dual-layer flow-diverting stent (FRED) for the treatment of intracranial aneurysms
  • Advances in endovascular aneurysm management: flow modulation techniques with braided mesh devices
  • Large Neck and Strong Ostium Inflow as the Potential Causes for Delayed Occlusion of Unruptured Sidewall Intracranial Aneurysms Treated by Flow Diverter
  • Flow diversion treatment of aneurysms of the complex region of the anterior communicating artery: which stent placement strategy should 'I use? A single center experience
  • On Flow Diversion: The Changing Landscape of Intracerebral Aneurysm Management
  • Safety and efficacy of the Derivo Embolization Device for the treatment of unruptured intracranial aneurysms: a multicentric study
  • Acutely Ruptured Intracranial Aneurysms Treated with Flow-Diverter Stents: A Systematic Review and Meta-Analysis
  • Feasibility, complications, morbidity, and mortality results at 6 months for aneurysm treatment with the Flow Re-Direction Endoluminal Device: report of SAFE study
  • European Multicenter Study for the Evaluation of a Dual-Layer Flow-Diverting Stent for Treatment of Wide-Neck Intracranial Aneurysms: The European Flow-Redirection Intraluminal Device Study
  • A comparison between the new Low-profile Visualized Intraluminal Support (LVIS Blue) stent and the Flow Redirection Endoluminal Device (FRED) in bench-top and cadaver studies
  • An outcomes-based grading scale for the evaluation of cerebral aneurysms treated with flow diversion
  • Thrombogenicity of flow diverters in an ex vivo shunt model: effect of phosphorylcholine surface modification
  • Multicenter Experience with FRED Jr Flow Re-Direction Endoluminal Device for Intracranial Aneurysms in Small Arteries
  • Use of flow diverters in the treatment of unruptured saccular aneurysms of the anterior cerebral artery
  • FRED Flow Diverter: A Study on Safety and Efficacy in a Consecutive Group of 50 Patients
  • Mid-term and long-term follow-up of intracranial aneurysms treated by the p64 Flow Modulation Device: a multicenter experience
  • Treatment of Intra- and Extracranial Aneurysms Using the Flow-Redirection Endoluminal Device: Multicenter Experience and Follow-Up Results
  • Wall Apposition Is a Key Factor for Aneurysm Occlusion after Flow Diversion: A Histologic Evaluation in 41 Rabbits
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Treatment of Proximal Posterior Inferior Cerebellar Artery Aneurysms by Intrasaccular Flow Disruption: A Multicenter Experience
  • Emergency Department Visits for Chronic Subdural Hematomas within 30 Days after Surgical Evacuation with and without Middle Meningeal Artery Embolization
  • Effect of the Shelving Technique on the Outcome of Embolization in Intracranial Bifurcation Aneurysms
Show more Interventional

Similar Articles

Advertisement

News and Updates

  • Lucien Levy Best Research Article Award
  • Thanks to our 2021 Distinguished Reviewers
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2022 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire