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Review ArticleReview Article
Open Access

Reversible Cerebral Vasoconstriction Syndrome, Part 1: Epidemiology, Pathogenesis, and Clinical Course

T.R. Miller, R. Shivashankar, M. Mossa-Basha and D. Gandhi
American Journal of Neuroradiology August 2015, 36 (8) 1392-1399; DOI: https://doi.org/10.3174/ajnr.A4214
T.R. Miller
aFrom the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland
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R. Shivashankar
aFrom the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland
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M. Mossa-Basha
bDepartment of Diagnostic Radiology (M.M.-B.), Section of Neuroradiology, University of Washington, Seattle, Washington.
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D. Gandhi
aFrom the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland
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Abstract

SUMMARY: Reversible cerebral vasoconstriction syndrome is a clinical and radiologic syndrome that represents a common presentation of a diverse group of disorders. The syndrome is characterized by thunderclap headache and reversible vasoconstriction of cerebral arteries, which can either be spontaneous or related to an exogenous trigger. The pathophysiology of reversible cerebral vasoconstriction syndrome is unknown, though alterations in cerebral vascular tone are thought to be a key underlying mechanism. The syndrome typically follows a benign course; however, reversible cerebral vasoconstriction syndrome may result in permanent disability or death in a small minority of patients secondary to complications such as ischemic stroke or intracranial hemorrhage.

ABBREVIATIONS:

RCVS
reversible cerebral vasoconstriction syndrome
PRES
posterior reversible encephalopathy syndrome
  • © 2015 by American Journal of Neuroradiology

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American Journal of Neuroradiology: 36 (8)
American Journal of Neuroradiology
Vol. 36, Issue 8
1 Aug 2015
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Reversible Cerebral Vasoconstriction Syndrome, Part 1: Epidemiology, Pathogenesis, and Clinical Course
T.R. Miller, R. Shivashankar, M. Mossa-Basha, D. Gandhi
American Journal of Neuroradiology Aug 2015, 36 (8) 1392-1399; DOI: 10.3174/ajnr.A4214

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Reversible Cerebral Vasoconstriction Syndrome, Part 1: Epidemiology, Pathogenesis, and Clinical Course
T.R. Miller, R. Shivashankar, M. Mossa-Basha, D. Gandhi
American Journal of Neuroradiology Aug 2015, 36 (8) 1392-1399; DOI: 10.3174/ajnr.A4214
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