Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Other Publications
    • ajnr

User menu

  • Subscribe
  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

  • Subscribe
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Publication Preview--Ahead of Print
    • Past Issue Archive
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • For Authors
  • About Us
    • About AJNR
    • Editors
    • American Society of Neuroradiology
  • Submit a Manuscript
  • Podcasts
    • Subscribe on iTunes
    • Subscribe on Stitcher
  • More
    • Subscribers
    • Permissions
    • Advertisers
    • Alerts
    • Feedback
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds
Research ArticleADULT BRAIN

Imaging Findings Associated with Space-Occupying Edema in Patients with Large Middle Cerebral Artery Infarcts

A.D. Horsch, J.W. Dankbaar, T.A. Stemerdink, E. Bennink, T. van Seeters, L.J. Kappelle, J. Hofmeijer, H.W. de Jong, Y. van der Graaf and B.K. Velthuis on behalf of the DUST investigators
American Journal of Neuroradiology May 2016, 37 (5) 831-837; DOI: https://doi.org/10.3174/ajnr.A4637
A.D. Horsch
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A.D. Horsch
J.W. Dankbaar
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.W. Dankbaar
T.A. Stemerdink
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T.A. Stemerdink
E. Bennink
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E. Bennink
T. van Seeters
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T. van Seeters
L.J. Kappelle
bNeurology (L.J.K.), Utrecht Stroke Center, University Medical Center Utrecht, Utrecht, the Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L.J. Kappelle
J. Hofmeijer
cDepartment of Neurology (J.H.), Rijnstate Hospital, Arnhem, the Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Hofmeijer
H.W. de Jong
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H.W. de Jong
Y. van der Graaf
dJulius Center for Health Sciences and Primary Care (Y.v.d.G.), Utrecht, the Netherlands.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Y. van der Graaf
B.K. Velthuis
aFrom the Departments of Radiology (A.D.H., J.W.D., T.A.S., E.B., T.v.S., H.W.d.J., B.K.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for B.K. Velthuis
  • Article
  • Figures & Data
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Hacke W,
    2. Schwab S,
    3. Horn M, et al
    . ‘Malignant’ middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol 1996;53:309–15 doi:10.1001/archneur.1996.00550040037012 pmid:8929152
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Berrouschot J,
    2. Sterker M,
    3. Bettin S, et al
    . Mortality of space-occupying (‘malignant’) middle cerebral artery infarction under conservative intensive care. Intensive Care Med 1998;24:620–23 doi:10.1007/s001340050625 pmid:9681786
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Heinsius T,
    2. Bogousslavsky J,
    3. Van Melle G
    . Large infarcts in the middle cerebral artery territory: etiology and outcome patterns. Neurology 1998;50:341–50 doi:10.1212/WNL.50.2.341 pmid:9484351
    Abstract/FREE Full Text
  4. 4.↵
    1. Vahedi K,
    2. Hofmeijer J,
    3. Juettler E, et al
    ; DECIMAL, DESTINY, and HAMLET investigators. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol 2007;6:215–22 doi:10.1016/S1474-4422(07)70036-4 pmid:17303527
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Hofmeijer J,
    2. Kappelle LJ,
    3. Algra A, et al
    ; HAMLET investigators. Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial. Lancet Neurol 2009;8:326–33 doi:10.1016/S1474-4422(09)70047-X pmid:19269254
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Arch AE,
    2. Sheth KN
    . Malignant cerebral edema after large anterior circulation infarction: a review. Curr Treat Options Cardiovasc Med 2014;16:275 doi:10.1007/s11936-013-0275-0 pmid:24390790
    CrossRefPubMed
  7. 7.↵
    1. Hofmeijer J,
    2. Algra A,
    3. Kappelle LJ, et al
    . Predictors of life-threatening brain edema in middle cerebral artery infarction. Cerebrovasc Dis 2008;25:176–84 doi:10.1159/000113736 pmid:18212524
    CrossRefPubMed
  8. 8.↵
    1. Rudolf J,
    2. Grond M,
    3. Stenzel C, et al
    . Incidence of space-occupying brain edema following systemic thrombolysis of acute supratentorial ischemia. Cerebrovasc Dis 1998;8:166–71 doi:10.1159/000015843 pmid:9619700
    CrossRefPubMed
  9. 9.↵
    1. Bektas H,
    2. Wu TC,
    3. Kasam M, et al
    . Increased blood-brain barrier permeability on perfusion CT might predict malignant middle cerebral artery infarction. Stroke 2010;41:2539–44 doi:10.1161/STROKEAHA.110.591362 pmid:20847316
    Abstract/FREE Full Text
  10. 10.↵
    1. Bennink E,
    2. Riordan AJ,
    3. Horsch AD, et al
    . A fast nonlinear regression method for estimating permeability in CT perfusion imaging. J Cereb Blood Flow Metab 2013;33:1743–51 doi:10.1038/jcbfm.2013.122 pmid:23881247
    Abstract/FREE Full Text
  11. 11.↵
    1. Sykora M,
    2. Steiner T,
    3. Rocco A, et al
    . Baroreflex sensitivity to predict malignant middle cerebral artery infarction. Stroke 2012;43:714–19 doi:10.1161/STROKEAHA.111.632778 pmid:22223241
    Abstract/FREE Full Text
  12. 12.↵
    1. Jaramillo A,
    2. Góngora-Rivera F,
    3. Labreuche J, et al
    . Predictors for malignant middle cerebral artery infarctions: a postmortem analysis. Neurology 2006;66:815–20 doi:10.1212/01.wnl.0000203649.60211.0e pmid:16567697
    Abstract/FREE Full Text
  13. 13.↵
    1. Wartenberg KE
    . Malignant middle cerebral artery infarction. Curr Opin Crit Care 2012;18:152–63 doi:10.1097/MCC.0b013e32835075c5 pmid:22322256
    CrossRefPubMed
  14. 14.↵
    1. Minnerup J,
    2. Wersching H,
    3. Ringelstein EB, et al
    . Prediction of malignant middle cerebral artery infarction using computed tomography-based intracranial volume reserve measurements. Stroke 2011;42:3403–09 doi:10.1161/STROKEAHA.111.619734 pmid:21903965
    Abstract/FREE Full Text
  15. 15.↵
    1. van Seeters T,
    2. Biessels GJ,
    3. van der Schaaf IC, et al
    . Prediction of outcome in patients with suspected acute ischaemic stroke with CT perfusion and CT angiography: the Dutch Acute Stroke Trial (DUST) study protocol. BMC Neurol 2014;14:37 doi:10.1186/1471-2377-14-37 pmid:24568540
    CrossRefPubMed
  16. 16.↵
    1. Barber PA,
    2. Demchuk AM,
    3. Zhang J, et al
    . Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy: ASPECTS Study Group—Alberta Stroke Programme Early CT Score. Lancet 2000;355:1670–74 doi:10.1016/S0140-6736(00)02237-6 pmid:10905241
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Hacke W,
    2. Kaste M,
    3. Fieschi C, et al
    . Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: the European Cooperative Acute Stroke Study (ECASS). JAMA 1995;274:1017–25 doi:10.1001/jama.274.13.1017 pmid:7563451
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Dohmen C,
    2. Galldiks N,
    3. Bosche B, et al
    . The severity of ischemia determines and predicts malignant brain edema in patients with large middle cerebral artery infarction. Cerebrovasc Dis 2012;33:1–87 doi:10.1159/000338951 pmid:22143164
    CrossRefPubMed
  19. 19.↵
    1. Walcott BP,
    2. Miller JC,
    3. Kwon CS, et al
    . Outcomes in severe middle cerebral artery ischemic stroke. Neurocrit Care 2014;21:20–26 doi:10.1007/s12028-013-9838-x pmid:23839704
    CrossRefPubMed
  20. 20.↵
    1. van Seeters T,
    2. Biessels GJ,
    3. Niesten JM, et al
    ; Dust Investigators. Reliability of visual assessment of non-contrast CT, CT angiography source images and CT perfusion in patients with suspected ischemic stroke. PLoS One 2013;8:e75615 doi:10.1371/journal.pone.0075615 pmid:24116061
    CrossRefPubMed
  21. 21.↵
    1. Kasner SE,
    2. Demchuk AM,
    3. Berrouschot J, et al
    . Predictors of fatal brain edema in massive hemispheric ischemic stroke. Stroke 2001;32:2117–23 doi:10.1161/hs0901.095719 pmid:11546905
    Abstract/FREE Full Text
  22. 22.↵
    1. Soares BP,
    2. Tong E,
    3. Hom J, et al
    . Reperfusion is a more accurate predictor of follow-up infarct volume than recanalization: a proof of concept using CT in acute ischemic stroke patients. Stroke 2010;41:e34–40 doi:10.1161/STROKEAHA.109.568766 pmid:19910542
    Abstract/FREE Full Text
  23. 23.↵
    1. Puetz V,
    2. Dzialowski I,
    3. Hill MD, et al
    ; Calgary CTA Study Group. Intracranial thrombus extent predicts clinical outcome, final infarct size and hemorrhagic transformation in ischemic stroke: the clot burden score. Int J Stroke 2008;3:230–36 doi:10.1111/j.1747-4949.2008.00221.x pmid:18811738
    Abstract/FREE Full Text
  24. 24.↵
    1. Tan IY,
    2. Demchuk AM,
    3. Hopyan J, et al
    . CT angiography clot burden score and collateral score: correlation with clinical and radiologic outcomes in acute middle cerebral artery infarct. AJNR Am J Neuroradiol 2009;30:525–31 doi:10.3174/ajnr.A1408 pmid:19147716
    Abstract/FREE Full Text
  25. 25.↵
    1. Tan JC,
    2. Dillon WP,
    3. Liu S, et al
    . Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients. Ann Neurol 2007;61:533–43 doi:10.1002/ana.21130 pmid:17431875
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. El-Mitwalli A,
    2. Saad M,
    3. Christou I, et al
    . Clinical and sonographic patterns of tandem internal carotid artery/middle cerebral artery occlusion in tissue plasminogen activator-treated patients. Stroke 2002;33:99–102 doi:10.1161/hs0102.101892 pmid:11779896
    Abstract/FREE Full Text
  27. 27.↵
    1. Tomsick T,
    2. Broderick J,
    3. Carrozella J, et al
    ; Interventional Management of Stroke II Investigators. Revascularization results in the Interventional Management of Stroke II trial. AJNR Am J Neuroradiol 2008;29:582–87 doi:10.3174/ajnr.A0843 pmid:18337393
    Abstract/FREE Full Text
  28. 28.↵
    1. Heo JH,
    2. Han SW,
    3. Lee SK
    . Free radicals as triggers of brain edema formation after stroke. Free Radic Biol Med 2005;39:51–70 doi:10.1016/j.freeradbiomed.2005.03.035 pmid:15925278
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Dohmen C,
    2. Bosche B,
    3. Graf R, et al
    . Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction. Stroke 2007;38:56–61 doi:10.1161/01.STR.0000251642.18522.b6 pmid:17122439
    Abstract/FREE Full Text
  30. 30.↵
    1. Thomalla G,
    2. Hartmann F,
    3. Juettler E, et al
    ; Clinical Trial Net of the German Competence Network Stroke. Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: a prospective multicenter observational study. Ann Neurol 2010;68:435–45 doi:10.1002/ana.22125 pmid:20865766
    CrossRefPubMed
  31. 31.↵
    1. Ito U,
    2. Go KG,
    3. Walker JT Jr., et al
    . Experimental cerebral ischemia in Mongolian gerbils. III: behaviour of the blood-brain barrier. Acta Neuropathol 1976;34:1–6 doi:10.1007/BF00684938 pmid:1251683
    CrossRefPubMed
  32. 32.↵
    1. Todd NV,
    2. Picozzi P,
    3. Crockard A, et al
    . Duration of ischemia influences the development and resolution of ischemic brain edema. Stroke 1986;17:466–71 doi:10.1161/01.STR.17.3.466 pmid:3715944
    Abstract/FREE Full Text
  33. 33.↵
    1. Grossman RI,
    2. Yousem DM
    . Neuroradiology: The Requisites. 2nd ed. Philadelphia: Mosby, Elsevier; 2003:261–63
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 37 (5)
American Journal of Neuroradiology
Vol. 37, Issue 5
1 May 2016
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Imaging Findings Associated with Space-Occupying Edema in Patients with Large Middle Cerebral Artery Infarcts
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Imaging Findings Associated with Space-Occupying Edema in Patients with Large Middle Cerebral Artery Infarcts
A.D. Horsch, J.W. Dankbaar, T.A. Stemerdink, E. Bennink, T. van Seeters, L.J. Kappelle, J. Hofmeijer, H.W. de Jong, Y. van der Graaf, B.K. Velthuis
American Journal of Neuroradiology May 2016, 37 (5) 831-837; DOI: 10.3174/ajnr.A4637

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Imaging Findings Associated with Space-Occupying Edema in Patients with Large Middle Cerebral Artery Infarcts
A.D. Horsch, J.W. Dankbaar, T.A. Stemerdink, E. Bennink, T. van Seeters, L.J. Kappelle, J. Hofmeijer, H.W. de Jong, Y. van der Graaf, B.K. Velthuis
American Journal of Neuroradiology May 2016, 37 (5) 831-837; DOI: 10.3174/ajnr.A4637
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Predictors of malignant brain edema after mechanical thrombectomy for acute ischemic stroke
  • Thalamic Diaschisis in Acute Ischemic Stroke: Occurrence, Perfusion Characteristics, and Impact on Outcome
  • Early Imaging Prediction of Malignant Cerebellar Edema Development in Acute Ischemic Stroke
  • A Biophysical Model for Cytotoxic Cell Swelling
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

ADULT BRAIN

  • CTA Evaluation of Basilar Septations: An Entity Better Characterized as Aberrant Basilar Fenestrations
  • Inversion Recovery Ultrashort TE MR Imaging of Myelin is Significantly Correlated with Disability in Patients with Multiple Sclerosis
  • A Stacked Generalization of 3D Orthogonal Deep Learning Convolutional Neural Networks for Improved Detection of White Matter Hyperintensities in 3D FLAIR Images
Show more ADULT BRAIN

INTERVENTIONAL

  • CTA Evaluation of Basilar Septations: An Entity Better Characterized as Aberrant Basilar Fenestrations
  • Inversion Recovery Ultrashort TE MR Imaging of Myelin is Significantly Correlated with Disability in Patients with Multiple Sclerosis
  • A Stacked Generalization of 3D Orthogonal Deep Learning Convolutional Neural Networks for Improved Detection of White Matter Hyperintensities in 3D FLAIR Images
Show more INTERVENTIONAL

Similar Articles

Advertisement

News and Updates

  • Lucien Levy Best Research Article Award
  • Thanks to our 2020 Distinguished Reviewers
  • Press Releases

Resources

  • Evidence-Based Medicine Level Guide
  • How to Participate in a Tweet Chat
  • AJNR Podcast Archive
  • Ideas for Publicizing Your Research
  • Librarian Resources
  • Terms and Conditions

Opportunities

  • Share Your Art in Perspectives
  • Get Peer Review Credit from Publons
  • Moderate a Tweet Chat

American Society of Neuroradiology

  • Neurographics
  • ASNR Annual Meeting
  • Fellowship Portal
  • Position Statements

© 2021 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire