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Letter

Macrocyclic Gadolinium-Based Contrast Agents Do Not Cause Hyperintensity in the Dentate Nucleus

T. Kanda, H. Oba, K. Toyoda and S. Furui
American Journal of Neuroradiology May 2016, 37 (5) E41; DOI: https://doi.org/10.3174/ajnr.A4710
T. Kanda
aDepartment of Radiology Teikyo University School of Medicine Itabashi-ku, Japan
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H. Oba
aDepartment of Radiology Teikyo University School of Medicine Itabashi-ku, Japan
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K. Toyoda
aDepartment of Radiology Teikyo University School of Medicine Itabashi-ku, Japan
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S. Furui
aDepartment of Radiology Teikyo University School of Medicine Itabashi-ku, Japan
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References

  1. 1.↵
    1. Ramalho J,
    2. Semelka RC,
    3. Ramalho M, et al
    . Gadolinium-based contrast agent accumulation and toxicity: an update. AJNR Am J Neuroradiol 2015 Dec 10. [Epub ahead of print] doi:10.3174/ajnr.A4615 pmid:26659341
    Abstract/FREE Full Text
  2. 2.↵
    1. Stojanov DA,
    2. Aracki-Trenkic A,
    3. Vojinovic S, et al
    . Increasing signal intensity within the dentate nucleus and globus pallidus on unenhanced T1W magnetic resonance images in patients with relapsing-remitting multiple sclerosis: correlation with cumulative dose of a macrocyclic gadolinium-based contrast agent, gadobutrol. Eur Radiol 2016;26:807–15 doi:10.1007/s00330-015-3879-9 pmid:26105022
    CrossRefPubMed
  3. 3.↵
    1. Kanda T,
    2. Oba H,
    3. Toyoda K, et al
    . Brain gadolinium deposition after administration of gadolinium-based contrast agents. Jpn J Radiol 2016;34:3–9 doi:10.1007/s11604-015-0503-5 pmid:26608061
    CrossRefPubMed
  4. 4.↵
    1. Radbruch A,
    2. Weberling LD,
    3. Kieslich PJ, et al
    . High-signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted images: evaluation of the macrocyclic gadolinium-based contrast agent gadobutrol. Invest Radiol 2015;50:805–10 doi:10.1097/RLI.0000000000000227 pmid:26523910
    CrossRefPubMed
  5. 5.↵
    1. Jost G,
    2. Lenhard DC,
    3. Sieber MA, et al
    . Signal increase on unenhanced T1-weighted images in the rat brain after repeated, extended doses of gadolinium-based contrast agents: comparison of linear and macrocyclic agents. Invest Radiol 2016;51:83–89 doi:10.1097/RLI.0000000000000242 pmid:26606548
    CrossRefPubMed
  6. 6.↵
    1. Kanda T,
    2. Fukusato T,
    3. Matsuda M, et al
    . Gadolinium-based contrast agent accumulates in the brain even in subjects without severe renal dysfunction: evaluation of autopsy brain specimens with inductively coupled plasma mass spectroscopy. Radiology 2015;276:228–32 doi:10.1148/radiol.2015142690 pmid:25942417
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  7. 7.↵
    1. McDonald RJ,
    2. McDonald JS,
    3. Kallmes DF, et al
    . Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology 2015;275:772–82 doi:10.1148/radiol.15150025 pmid:25742194
    CrossRefPubMed
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American Journal of Neuroradiology: 37 (5)
American Journal of Neuroradiology
Vol. 37, Issue 5
1 May 2016
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Macrocyclic Gadolinium-Based Contrast Agents Do Not Cause Hyperintensity in the Dentate Nucleus
T. Kanda, H. Oba, K. Toyoda, S. Furui
American Journal of Neuroradiology May 2016, 37 (5) E41; DOI: 10.3174/ajnr.A4710

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Macrocyclic Gadolinium-Based Contrast Agents Do Not Cause Hyperintensity in the Dentate Nucleus
T. Kanda, H. Oba, K. Toyoda, S. Furui
American Journal of Neuroradiology May 2016, 37 (5) E41; DOI: 10.3174/ajnr.A4710
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