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Research ArticlePediatrics
Open Access

MR Imaging–Based Radiomic Signatures of Distinct Molecular Subgroups of Medulloblastoma

M. Iv, M. Zhou, K. Shpanskaya, S. Perreault, Z. Wang, E. Tranvinh, B. Lanzman, S. Vajapeyam, N.A. Vitanza, P.G. Fisher, Y.J. Cho, S. Laughlin, V. Ramaswamy, M.D. Taylor, S.H. Cheshier, G.A. Grant, T. Young Poussaint, O. Gevaert and K.W. Yeom
American Journal of Neuroradiology January 2019, 40 (1) 154-161; DOI: https://doi.org/10.3174/ajnr.A5899
M. Iv
aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
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M. Zhou
aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
dStanford Center for Biomedical Informatics (M.Z., O.G., Z.W.)
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K. Shpanskaya
aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
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S. Perreault
fDepartment of Pediatrics (S.P.), Pediatric Neurology, Centre Hospitalier Universitaire Sainte Justine, University of Montréal, Montreal, Quebec, Canada
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Z. Wang
dStanford Center for Biomedical Informatics (M.Z., O.G., Z.W.)
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E. Tranvinh
aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
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B. Lanzman
aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
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S. Vajapeyam
gDepartment of Radiology (S.V., T.Y.P.), Boston Children's Hospital, Harvard University, Boston, Massachusetts
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N.A. Vitanza
hDepartment Pediatrics Hematology-Oncology (N.A.V.), Seattle Children's Hospital, University of Washington, Seattle, Washington
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P.G. Fisher
bDepartment of Pediatrics (P.G.F.), Pediatric Neurology
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Y.J. Cho
iDepartment of Pediatrics (Y.J.C.), Pediatric Neurology, Oregon Health & Science University, Portland, Oregon
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S. Laughlin
jDepartments of Radiology, Neuro-Oncology, and Neurosurgery (S.L., V.R., M.D.T.), Hospital for Sick Children, Toronto, Ontario, Canada
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V. Ramaswamy
jDepartments of Radiology, Neuro-Oncology, and Neurosurgery (S.L., V.R., M.D.T.), Hospital for Sick Children, Toronto, Ontario, Canada
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M.D. Taylor
jDepartments of Radiology, Neuro-Oncology, and Neurosurgery (S.L., V.R., M.D.T.), Hospital for Sick Children, Toronto, Ontario, Canada
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S.H. Cheshier
kDepartment of Neurosurgery (S.H.C.), Pediatric Neurosurgery, University of Utah, Salt Lake City, Utah.
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G.A. Grant
cDepartment of Neurosurgery (G.A.G.), Pediatric Neurosurgery, Lucile Packard Children's Hospital, Stanford University, Palo Alto, California
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T. Young Poussaint
gDepartment of Radiology (S.V., T.Y.P.), Boston Children's Hospital, Harvard University, Boston, Massachusetts
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O. Gevaert
dStanford Center for Biomedical Informatics (M.Z., O.G., Z.W.)
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K.W. Yeom
aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
eDepartment of Radiology (K.W.Y.), Artificial Intelligence in Medicine and Imaging, Stanford University, Stanford, California
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Article Information

vol. 40 no. 1 154-161
DOI 
https://doi.org/10.3174/ajnr.A5899
PubMed 
30523141

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received June 29, 2018
  • Accepted after revision October 6, 2018
  • Published online January 11, 2019.

Article Versions

  • Latest version (December 6, 2018 - 07:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2019 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. M. Iva,
  2. M. Zhoua,d,
  3. K. Shpanskayaa,
  4. S. Perreaultf,
  5. Z. Wangd,
  6. E. Tranvinha,
  7. B. Lanzmana,
  8. S. Vajapeyamg,
  9. N.A. Vitanzah,
  10. P.G. Fisherb,
  11. Y.J. Choi,
  12. S. Laughlinj,
  13. V. Ramaswamyj,
  14. M.D. Taylorj,
  15. S.H. Cheshierk,
  16. G.A. Grantc,
  17. T. Young Poussaintg,
  18. O. Gevaertd and
  19. K.W. Yeoma,e
  1. aFrom the Department of Radiology (M.I., M.Z., K.S., E.T., B.L., K.W.Y.)
  2. bDepartment of Pediatrics (P.G.F.), Pediatric Neurology
  3. cDepartment of Neurosurgery (G.A.G.), Pediatric Neurosurgery, Lucile Packard Children's Hospital, Stanford University, Palo Alto, California
  4. dStanford Center for Biomedical Informatics (M.Z., O.G., Z.W.)
  5. eDepartment of Radiology (K.W.Y.), Artificial Intelligence in Medicine and Imaging, Stanford University, Stanford, California
  6. fDepartment of Pediatrics (S.P.), Pediatric Neurology, Centre Hospitalier Universitaire Sainte Justine, University of Montréal, Montreal, Quebec, Canada
  7. gDepartment of Radiology (S.V., T.Y.P.), Boston Children's Hospital, Harvard University, Boston, Massachusetts
  8. hDepartment Pediatrics Hematology-Oncology (N.A.V.), Seattle Children's Hospital, University of Washington, Seattle, Washington
  9. iDepartment of Pediatrics (Y.J.C.), Pediatric Neurology, Oregon Health & Science University, Portland, Oregon
  10. jDepartments of Radiology, Neuro-Oncology, and Neurosurgery (S.L., V.R., M.D.T.), Hospital for Sick Children, Toronto, Ontario, Canada
  11. kDepartment of Neurosurgery (S.H.C.), Pediatric Neurosurgery, University of Utah, Salt Lake City, Utah.
  1. Please address correspondence to Kristen W. Yeom, MD, Lucile Packard Children's Hospital, Stanford University Medical Center, Department of Radiology, Pediatric MRI and CT, Room 0511, 725 Welch Rd, Palo Alto, CA 94304; e-mail: kyeom{at}stanford.edu.
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Funding

  • Collaborative Ependymoma Research Network

  • National Institute of Biomedical Imaging and Bioengineering

    R01EB020527

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MR Imaging–Based Radiomic Signatures of Distinct Molecular Subgroups of Medulloblastoma
M. Iv, M. Zhou, K. Shpanskaya, S. Perreault, Z. Wang, E. Tranvinh, B. Lanzman, S. Vajapeyam, N.A. Vitanza, P.G. Fisher, Y.J. Cho, S. Laughlin, V. Ramaswamy, M.D. Taylor, S.H. Cheshier, G.A. Grant, T. Young Poussaint, O. Gevaert, K.W. Yeom
American Journal of Neuroradiology Jan 2019, 40 (1) 154-161; DOI: 10.3174/ajnr.A5899

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MR Imaging–Based Radiomic Signatures of Distinct Molecular Subgroups of Medulloblastoma
M. Iv, M. Zhou, K. Shpanskaya, S. Perreault, Z. Wang, E. Tranvinh, B. Lanzman, S. Vajapeyam, N.A. Vitanza, P.G. Fisher, Y.J. Cho, S. Laughlin, V. Ramaswamy, M.D. Taylor, S.H. Cheshier, G.A. Grant, T. Young Poussaint, O. Gevaert, K.W. Yeom
American Journal of Neuroradiology Jan 2019, 40 (1) 154-161; DOI: 10.3174/ajnr.A5899
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