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Research ArticleAdult Brain
Open Access

Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation

A. Hagiwara, Y. Otsuka, M. Hori, Y. Tachibana, K. Yokoyama, S. Fujita, C. Andica, K. Kamagata, R. Irie, S. Koshino, T. Maekawa, L. Chougar, A. Wada, M.Y. Takemura, N. Hattori and S. Aoki
American Journal of Neuroradiology February 2019, 40 (2) 224-230; DOI: https://doi.org/10.3174/ajnr.A5927
A. Hagiwara
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
cDepartment of Radiology (A.H., R.I., S.K., T.M.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
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  • ORCID record for A. Hagiwara
Y. Otsuka
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
dMilliman Inc (Y.O.). Tokyo, Japan
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  • ORCID record for Y. Otsuka
M. Hori
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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Y. Tachibana
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
eApplied MRI Research (Y.T.), Department of Molecular Imaging and Theranostics, National Institute of Radiological Sciences, Chiba, Japan
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  • ORCID record for Y. Tachibana
K. Yokoyama
bNeurology (K.Y., N.H.), Juntendo University School of Medicine, Tokyo, Japan
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  • ORCID record for K. Yokoyama
S. Fujita
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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C. Andica
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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K. Kamagata
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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R. Irie
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
cDepartment of Radiology (A.H., R.I., S.K., T.M.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
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S. Koshino
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
cDepartment of Radiology (A.H., R.I., S.K., T.M.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
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T. Maekawa
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
cDepartment of Radiology (A.H., R.I., S.K., T.M.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
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L. Chougar
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
fDepartment of Radiology (L.C.), Hopital Saint-Joseph, Paris, France; and Department of Radiological Sciences.
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A. Wada
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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M.Y. Takemura
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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N. Hattori
bNeurology (K.Y., N.H.), Juntendo University School of Medicine, Tokyo, Japan
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S. Aoki
aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
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Article Information

vol. 40 no. 2 224-230
DOI 
https://doi.org/10.3174/ajnr.A5927
PubMed 
30630834

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received September 6, 2018
  • Accepted after revision November 15, 2018
  • Published online February 13, 2019.

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  • Latest version (January 10, 2019 - 07:12).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2019 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. A. Hagiwaraa,c,
  2. Y. Otsukaa,d,
  3. M. Horia,
  4. Y. Tachibanaa,e,
  5. K. Yokoyamab,
  6. S. Fujitaa,
  7. C. Andicaa,
  8. K. Kamagataa,
  9. R. Iriea,c,
  10. S. Koshinoa,c,
  11. T. Maekawaa,c,
  12. L. Chougara,f,
  13. A. Wadaa,
  14. M.Y. Takemuraa,
  15. N. Hattorib and
  16. S. Aokia
  1. aFrom the Departments of Radiology (A.H., Y.O., M.H., Y.T., S.F., C.A., K.K., R.I., S.K., T.M., L.C., A.W., M.Y.T., S.A.)
  2. bNeurology (K.Y., N.H.), Juntendo University School of Medicine, Tokyo, Japan
  3. cDepartment of Radiology (A.H., R.I., S.K., T.M.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  4. dMilliman Inc (Y.O.). Tokyo, Japan
  5. eApplied MRI Research (Y.T.), Department of Molecular Imaging and Theranostics, National Institute of Radiological Sciences, Chiba, Japan
  6. fDepartment of Radiology (L.C.), Hopital Saint-Joseph, Paris, France; and Department of Radiological Sciences.
  1. Please address correspondence to Akifumi Hagiwara, MD, Department of Radiology, Juntendo University School of Medicine, 1-2-1, Hongo, Bunkyo-ku, Tokyo, Japan, 113-8421; e-mail: a-hagiwara{at}juntendo.ac.jp
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Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation
A. Hagiwara, Y. Otsuka, M. Hori, Y. Tachibana, K. Yokoyama, S. Fujita, C. Andica, K. Kamagata, R. Irie, S. Koshino, T. Maekawa, L. Chougar, A. Wada, M.Y. Takemura, N. Hattori, S. Aoki
American Journal of Neuroradiology Feb 2019, 40 (2) 224-230; DOI: 10.3174/ajnr.A5927

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Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation
A. Hagiwara, Y. Otsuka, M. Hori, Y. Tachibana, K. Yokoyama, S. Fujita, C. Andica, K. Kamagata, R. Irie, S. Koshino, T. Maekawa, L. Chougar, A. Wada, M.Y. Takemura, N. Hattori, S. Aoki
American Journal of Neuroradiology Feb 2019, 40 (2) 224-230; DOI: 10.3174/ajnr.A5927
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