Index by author
A
Abdulla, S.
- Adult BrainYou have accessDecreased Subcortical T2 FLAIR Signal Associated with SeizuresP. Nicholson, S. Abdulla, L. Alshafai, D.M. Mandell and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 111-114; DOI: https://doi.org/10.3174/ajnr.A6328
Ahmed, R.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Ahn, S.H.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Aigner, A.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Alaraj, A.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Almekhlafi, M.A.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Alshafai, L.
- Adult BrainYou have accessDecreased Subcortical T2 FLAIR Signal Associated with SeizuresP. Nicholson, S. Abdulla, L. Alshafai, D.M. Mandell and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 111-114; DOI: https://doi.org/10.3174/ajnr.A6328
Arai, N.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Arevalo, Y.A.
- Adult BrainYou have accessDiffusion Properties of Normal-Appearing White Matter Microstructure and Severity of Motor Impairment in Acute Ischemic StrokeC. Ingo, C. Lin, J. Higgins, Y.A. Arevalo and S. PrabhakaranAmerican Journal of Neuroradiology January 2020, 41 (1) 71-78; DOI: https://doi.org/10.3174/ajnr.A6357
Azuma, M.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
B
Baek, J.H.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Balchandani, P.
- Adult BrainOpen AccessEmerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future DirectionsJ.W. Rutland, B.N. Delman, C.M. Gill, C. Zhu, R.K. Shrivastava and P. BalchandaniAmerican Journal of Neuroradiology January 2020, 41 (1) 2-9; DOI: https://doi.org/10.3174/ajnr.A6344
Banerjee, M.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessVessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya DiseaseA. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand SudhirAmerican Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360
Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.
Bartha-Doering, L.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Baumgartner, C.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Bay, C.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Beall, D.
- EDITOR'S CHOICESpineYou have accessNumber Needed to Treat with Vertebral Augmentation to Save a LifeJ.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. OngAmerican Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367
The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.
Beheshtian, E.
- You have accessRedundant Neurovascular Imaging: Who Is to Blame and What Is the Value?E. Beheshtian, S. Emamzadehfard, S. Sahraian, R. Jalilianhasanpour and D.M. YousemAmerican Journal of Neuroradiology January 2020, 41 (1) 35-39; DOI: https://doi.org/10.3174/ajnr.A6329
Benson, J.C
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Berndt, M.T.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Bhadelia, R.A.
- Adult BrainYou have accessUnilateral Nonvisualization of a Transverse Dural Sinus on Phase-Contrast MRV: Frequency and Differentiation from Sinus Thrombosis on Noncontrast MRIY.-M. Chang, A.L. Kuhn, N. Porbandarwala, R. Rojas, V. Ivanovic and R.A. BhadeliaAmerican Journal of Neuroradiology January 2020, 41 (1) 115-121; DOI: https://doi.org/10.3174/ajnr.A6337
Bhatia, K.D.
- PediatricsYou have accessAcute Cortical Lesions in MELAS Syndrome: Anatomic Distribution, Symmetry, and EvolutionK.D. Bhatia, P. Krishnan, H. Kortman, J. Klostranec and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 167-173; DOI: https://doi.org/10.3174/ajnr.A6325
Blitz, A.M.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
Blomlie, V.
- LETTEROpen AccessManganese Uptake and Accumulation in the Human BrainV. Blomlie, R. Sivanandan and P. JyngeAmerican Journal of Neuroradiology January 2020, 41 (1) E3; DOI: https://doi.org/10.3174/ajnr.A6347
Boeckh-Behrens, T.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Bonafe, A.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Bonelli, S.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Bonham, L.W
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
Boo, S.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Bozkaya, H.
- InterventionalYou have accessReduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?I. Oran, C. Cinar, H. Bozkaya, M. Parildar and S. DumanAmerican Journal of Neuroradiology January 2020, 41 (1) 140-146; DOI: https://doi.org/10.3174/ajnr.A6343
Brekenfeld, C.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Brinjikji, W.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Broocks, G.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Byrne, D.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
C
Cagnazzo, F.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Carpenter, J.S.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Carr, C.M.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Carter, N.S.
- EDITOR'S CHOICESpineYou have accessNumber Needed to Treat with Vertebral Augmentation to Save a LifeJ.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. OngAmerican Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367
The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.
Chagnon, M.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Chandra, R.V.
- EDITOR'S CHOICESpineYou have accessNumber Needed to Treat with Vertebral Augmentation to Save a LifeJ.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. OngAmerican Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367
The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.
Chandrasekharan, K.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessVessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya DiseaseA. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand SudhirAmerican Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360
Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.
Chang, Y.-M.
- Adult BrainYou have accessUnilateral Nonvisualization of a Transverse Dural Sinus on Phase-Contrast MRV: Frequency and Differentiation from Sinus Thrombosis on Noncontrast MRIY.-M. Chang, A.L. Kuhn, N. Porbandarwala, R. Rojas, V. Ivanovic and R.A. BhadeliaAmerican Journal of Neuroradiology January 2020, 41 (1) 115-121; DOI: https://doi.org/10.3174/ajnr.A6337
Chen, X.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Cho, S.J.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Choi, S.H.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Choi, Y.J.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Chung, S.R.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Cinar, C.
- InterventionalYou have accessReduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?I. Oran, C. Cinar, H. Bozkaya, M. Parildar and S. DumanAmerican Journal of Neuroradiology January 2020, 41 (1) 140-146; DOI: https://doi.org/10.3174/ajnr.A6343
Corrêa, D.G.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Costalat, V.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Craig, P.G.
- Adult BrainOpen AccessResponse Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced TechniquesD.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite and B. PoliceniAmerican Journal of Neuroradiology January 2020, 41 (1) 10-20; DOI: https://doi.org/10.3174/ajnr.A6358
Cristiano, B.C.
- SpineYou have accessSimple Fluoroscopy-Guided Transforaminal Lumbar Puncture: Safety and Effectiveness of a Coaxial Curved-Needle Technique in Patients with Spinal Muscular Atrophy and Complex SpinesJ.P. Jacobson, B.C. Cristiano and D.R. HossAmerican Journal of Neuroradiology January 2020, 41 (1) 183-188; DOI: https://doi.org/10.3174/ajnr.A6351
Cutsforth-Gregory, J.K.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Czech, T.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
D
da Cruz, L.C.H.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Dargazanli, C.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Darsaut, T.E.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
de Almeida Di Maio Ferreira, F.C.P.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
de Andrade Lopes, J.M.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Deb-Chatterji, M.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Delman, B.N.
- Adult BrainOpen AccessEmerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future DirectionsJ.W. Rutland, B.N. Delman, C.M. Gill, C. Zhu, R.K. Shrivastava and P. BalchandaniAmerican Journal of Neuroradiology January 2020, 41 (1) 2-9; DOI: https://doi.org/10.3174/ajnr.A6344
Demchuk, A.M.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Derraz, I.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
deVeber, G.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
di Carlo, D.T.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Diehn, F.E.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Dirks, P.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Dlamini, N.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Dong, L.
- LETTERYou have accessRegarding “the Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, L. Dong, H. Wang and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E2; DOI: https://doi.org/10.3174/ajnr.A6388
- LETTERYou have accessRegarding “The Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, H. Wang, L. Dong and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E1; DOI: https://doi.org/10.3174/ajnr.A6340
Dorfer, C.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Duman, S.
- InterventionalYou have accessReduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?I. Oran, C. Cinar, H. Bozkaya, M. Parildar and S. DumanAmerican Journal of Neuroradiology January 2020, 41 (1) 140-146; DOI: https://doi.org/10.3174/ajnr.A6343
E
Emamzadehfard, S.
- You have accessRedundant Neurovascular Imaging: Who Is to Blame and What Is the Value?E. Beheshtian, S. Emamzadehfard, S. Sahraian, R. Jalilianhasanpour and D.M. YousemAmerican Journal of Neuroradiology January 2020, 41 (1) 35-39; DOI: https://doi.org/10.3174/ajnr.A6329
Evans, A.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
F
Fainardi, E.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Faizy, T.D.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Farb, R.I.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Fiehler, J.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Field, T.S.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Fiorella, D.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Flottmann, F.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Foesleitner, O.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Freddi, T. A. L.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Friedrich, B.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Frohbergh, M.
- EDITOR'S CHOICESpineYou have accessNumber Needed to Treat with Vertebral Augmentation to Save a LifeJ.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. OngAmerican Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367
The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.
G
Gascou, G.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Ghostine, J.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Gill, C.M.
- Adult BrainOpen AccessEmerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future DirectionsJ.W. Rutland, B.N. Delman, C.M. Gill, C. Zhu, R.K. Shrivastava and P. BalchandaniAmerican Journal of Neuroradiology January 2020, 41 (1) 2-9; DOI: https://doi.org/10.3174/ajnr.A6344
Godoy, L.F.
- Adult BrainOpen AccessResponse Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced TechniquesD.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite and B. PoliceniAmerican Journal of Neuroradiology January 2020, 41 (1) 10-20; DOI: https://doi.org/10.3174/ajnr.A6358
Goyal, M.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Gujar, S.K.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
H
Hainc, Nicolin
- You have accessPerspectivesNicolin HaincAmerican Journal of Neuroradiology January 2020, 41 (1) 1; DOI: https://doi.org/10.3174/ajnr.P0086
Hainfellner, J.A.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Hak, J.F.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Han, W.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Heran, M.K.S.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Higgins, J.
- Adult BrainYou have accessDiffusion Properties of Normal-Appearing White Matter Microstructure and Severity of Motor Impairment in Acute Ischemic StrokeC. Ingo, C. Lin, J. Higgins, Y.A. Arevalo and S. PrabhakaranAmerican Journal of Neuroradiology January 2020, 41 (1) 71-78; DOI: https://doi.org/10.3174/ajnr.A6357
Hill, M.D.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Hirai, T.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
Hirsch, J.A.
- EDITOR'S CHOICESpineYou have accessNumber Needed to Treat with Vertebral Augmentation to Save a LifeJ.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. OngAmerican Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367
The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.
Hoss, D.R.
- SpineYou have accessSimple Fluoroscopy-Guided Transforaminal Lumbar Puncture: Safety and Effectiveness of a Coaxial Curved-Needle Technique in Patients with Spinal Muscular Atrophy and Complex SpinesJ.P. Jacobson, B.C. Cristiano and D.R. HossAmerican Journal of Neuroradiology January 2020, 41 (1) 183-188; DOI: https://doi.org/10.3174/ajnr.A6351
Huynh, P.P.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
Hwang, I.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
I
Iancu, D.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Ingo, C.
- Adult BrainYou have accessDiffusion Properties of Normal-Appearing White Matter Microstructure and Severity of Motor Impairment in Acute Ischemic StrokeC. Ingo, C. Lin, J. Higgins, Y.A. Arevalo and S. PrabhakaranAmerican Journal of Neuroradiology January 2020, 41 (1) 71-78; DOI: https://doi.org/10.3174/ajnr.A6357
Issleib, M.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Ivanovic, V.
- Adult BrainYou have accessUnilateral Nonvisualization of a Transverse Dural Sinus on Phase-Contrast MRV: Frequency and Differentiation from Sinus Thrombosis on Noncontrast MRIY.-M. Chang, A.L. Kuhn, N. Porbandarwala, R. Rojas, V. Ivanovic and R.A. BhadeliaAmerican Journal of Neuroradiology January 2020, 41 (1) 115-121; DOI: https://doi.org/10.3174/ajnr.A6337
J
Jacobson, J.P.
- SpineYou have accessSimple Fluoroscopy-Guided Transforaminal Lumbar Puncture: Safety and Effectiveness of a Coaxial Curved-Needle Technique in Patients with Spinal Muscular Atrophy and Complex SpinesJ.P. Jacobson, B.C. Cristiano and D.R. HossAmerican Journal of Neuroradiology January 2020, 41 (1) 183-188; DOI: https://doi.org/10.3174/ajnr.A6351
Jalilianhasanpour, R.
- You have accessRedundant Neurovascular Imaging: Who Is to Blame and What Is the Value?E. Beheshtian, S. Emamzadehfard, S. Sahraian, R. Jalilianhasanpour and D.M. YousemAmerican Journal of Neuroradiology January 2020, 41 (1) 35-39; DOI: https://doi.org/10.3174/ajnr.A6329
Jayanand Sudhir, B.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessVessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya DiseaseA. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand SudhirAmerican Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360
Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.
Jayaraman, M.V.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Jynge, P.
- LETTEROpen AccessManganese Uptake and Accumulation in the Human BrainV. Blomlie, R. Sivanandan and P. JyngeAmerican Journal of Neuroradiology January 2020, 41 (1) E3; DOI: https://doi.org/10.3174/ajnr.A6347
K
Kaesmacher, J.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Kan, H.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Kang, K.M.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Kasai, H.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Kasprian, G.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Kathuveetil, A.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessVessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya DiseaseA. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand SudhirAmerican Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360
Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.
Khant, Z.A.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
Khaw, A.V.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Kim, D.K.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Kim, I.H.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Kim, J.-H.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Kim, T.M.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Kirkham, F.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Kitajima, M.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
Klostranec, J.
- PediatricsYou have accessAcute Cortical Lesions in MELAS Syndrome: Anatomic Distribution, Symmetry, and EvolutionK.D. Bhatia, P. Krishnan, H. Kortman, J. Klostranec and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 167-173; DOI: https://doi.org/10.3174/ajnr.A6325
Kortman, H.
- PediatricsYou have accessAcute Cortical Lesions in MELAS Syndrome: Anatomic Distribution, Symmetry, and EvolutionK.D. Bhatia, P. Krishnan, H. Kortman, J. Klostranec and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 167-173; DOI: https://doi.org/10.3174/ajnr.A6325
Krauel, J.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Krings, T.
- Adult BrainYou have accessDecreased Subcortical T2 FLAIR Signal Associated with SeizuresP. Nicholson, S. Abdulla, L. Alshafai, D.M. Mandell and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 111-114; DOI: https://doi.org/10.3174/ajnr.A6328
- PediatricsYou have accessAcute Cortical Lesions in MELAS Syndrome: Anatomic Distribution, Symmetry, and EvolutionK.D. Bhatia, P. Krishnan, H. Kortman, J. Klostranec and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 167-173; DOI: https://doi.org/10.3174/ajnr.A6325
Krishnan, P.
- PediatricsYou have accessAcute Cortical Lesions in MELAS Syndrome: Anatomic Distribution, Symmetry, and EvolutionK.D. Bhatia, P. Krishnan, H. Kortman, J. Klostranec and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 167-173; DOI: https://doi.org/10.3174/ajnr.A6325
Kuhn, A.L.
- Adult BrainYou have accessUnilateral Nonvisualization of a Transverse Dural Sinus on Phase-Contrast MRV: Frequency and Differentiation from Sinus Thrombosis on Noncontrast MRIY.-M. Chang, A.L. Kuhn, N. Porbandarwala, R. Rojas, V. Ivanovic and R.A. BhadeliaAmerican Journal of Neuroradiology January 2020, 41 (1) 115-121; DOI: https://doi.org/10.3174/ajnr.A6337
Kunitomo, H.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Kunz, W.G.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Kvamme, P.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
L
Langs, G.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Lavoie, P.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Leao, D.J.
- Adult BrainOpen AccessResponse Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced TechniquesD.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite and B. PoliceniAmerican Journal of Neuroradiology January 2020, 41 (1) 10-20; DOI: https://doi.org/10.3174/ajnr.A6358
Lee, J.H.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Lee, M.K.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Lee, S.-T.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Lefevre, P.-H.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Lehman, V.T.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Leischner, H.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Leite, C.C.
- Adult BrainOpen AccessResponse Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced TechniquesD.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite and B. PoliceniAmerican Journal of Neuroradiology January 2020, 41 (1) 10-20; DOI: https://doi.org/10.3174/ajnr.A6358
Li, A.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Li, Y.
- LETTERYou have accessRegarding “the Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, L. Dong, H. Wang and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E2; DOI: https://doi.org/10.3174/ajnr.A6388
- LETTERYou have accessRegarding “The Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, H. Wang, L. Dong and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E1; DOI: https://doi.org/10.3174/ajnr.A6340
Liebo, G.B.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Lin, C.
- Adult BrainYou have accessDiffusion Properties of Normal-Appearing White Matter Microstructure and Severity of Motor Impairment in Acute Ischemic StrokeC. Ingo, C. Lin, J. Higgins, Y.A. Arevalo and S. PrabhakaranAmerican Journal of Neuroradiology January 2020, 41 (1) 71-78; DOI: https://doi.org/10.3174/ajnr.A6357
Logan, W.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Lopes, F.P.P.L.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Luciano, M.G.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
M
MacGregor, D.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Maegerlein, C.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Mandell, D.M.
- Adult BrainYou have accessDecreased Subcortical T2 FLAIR Signal Associated with SeizuresP. Nicholson, S. Abdulla, L. Alshafai, D.M. Mandell and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 111-114; DOI: https://doi.org/10.3174/ajnr.A6328
McTaggart, R.A.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Mendes-Pereira, V.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Menon, B.K.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Miskin, N.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Mitha, A.P.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Miyati, T.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Moghekar, A.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
Moharir, M.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Mönch, S.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Moreira, M.E.L.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Morris, J.M.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Morris, P.P.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
Moser, D.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Mück, F.G.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Murray, N.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
N
Najm, M.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Nenning, K.-H.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Nguyen, T.N.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Nicholson, P.
- Adult BrainYou have accessDecreased Subcortical T2 FLAIR Signal Associated with SeizuresP. Nicholson, S. Abdulla, L. Alshafai, D.M. Mandell and T. KringsAmerican Journal of Neuroradiology January 2020, 41 (1) 111-114; DOI: https://doi.org/10.3174/ajnr.A6328
Niu, B.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
O
Oakes, T.R.
- Adult BrainOpen AccessStructural and Volumetric Brain MRI Findings in Mild Traumatic Brain InjuryJ.B. Patel, S.H. Wilson, T.R. Oakes, P. Santhanam and L.K. WeaverAmerican Journal of Neuroradiology January 2020, 41 (1) 92-99; DOI: https://doi.org/10.3174/ajnr.A6346
Ogawa, M.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Omori, K.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Ong, K.
- EDITOR'S CHOICESpineYou have accessNumber Needed to Treat with Vertebral Augmentation to Save a LifeJ.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. OngAmerican Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367
The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.
Oran, I.
- InterventionalYou have accessReduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?I. Oran, C. Cinar, H. Bozkaya, M. Parildar and S. DumanAmerican Journal of Neuroradiology January 2020, 41 (1) 140-146; DOI: https://doi.org/10.3174/ajnr.A6343
P
Parildar, M.
- InterventionalYou have accessReduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?I. Oran, C. Cinar, H. Bozkaya, M. Parildar and S. DumanAmerican Journal of Neuroradiology January 2020, 41 (1) 140-146; DOI: https://doi.org/10.3174/ajnr.A6343
Park, C.-K.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Park, S.-H.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Pataraia, E.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Patel, J.B.
- Adult BrainOpen AccessStructural and Volumetric Brain MRI Findings in Mild Traumatic Brain InjuryJ.B. Patel, S.H. Wilson, T.R. Oakes, P. Santhanam and L.K. WeaverAmerican Journal of Neuroradiology January 2020, 41 (1) 92-99; DOI: https://doi.org/10.3174/ajnr.A6346
Perrini, P.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Policeni, B.
- Adult BrainOpen AccessResponse Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced TechniquesD.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite and B. PoliceniAmerican Journal of Neuroradiology January 2020, 41 (1) 10-20; DOI: https://doi.org/10.3174/ajnr.A6358
Porbandarwala, N.
- Adult BrainYou have accessUnilateral Nonvisualization of a Transverse Dural Sinus on Phase-Contrast MRV: Frequency and Differentiation from Sinus Thrombosis on Noncontrast MRIY.-M. Chang, A.L. Kuhn, N. Porbandarwala, R. Rojas, V. Ivanovic and R.A. BhadeliaAmerican Journal of Neuroradiology January 2020, 41 (1) 115-121; DOI: https://doi.org/10.3174/ajnr.A6337
Prabhakaran, S.
- Adult BrainYou have accessDiffusion Properties of Normal-Appearing White Matter Microstructure and Severity of Motor Impairment in Acute Ischemic StrokeC. Ingo, C. Lin, J. Higgins, Y.A. Arevalo and S. PrabhakaranAmerican Journal of Neuroradiology January 2020, 41 (1) 71-78; DOI: https://doi.org/10.3174/ajnr.A6357
Prayer, D.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Q
Qin, L.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
R
Raymond, J.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Rempel, J.L.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Rigamonti, D.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
Riquelme, C.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessFlow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-AnalysisF. Cagnazzo, P.-H. Lefevre, I. Derraz, C. Dargazanli, G. Gascou, D.T. di Carlo, P. Perrini, R. Ahmed, J.F. Hak, C. Riquelme, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology January 2020, 41 (1) 134-139; DOI: https://doi.org/10.3174/ajnr.A6352
The authors’ aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions. Fifteen studies (213 aneurysms) were included in the analysis. The long-term adequate occlusion rate was 85.3%. Treatment-related complications were 17.4%. Overall, 15% were ischemic events. They conclude that unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with a flow-diversion strategy. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (>10 mm) significantly increased the risk of procedure-related adverse events among nonsaccular lesions.
Robertson, A.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Rohr, A.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Rohr, B.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Rojas, R.
- Adult BrainYou have accessUnilateral Nonvisualization of a Transverse Dural Sinus on Phase-Contrast MRV: Frequency and Differentiation from Sinus Thrombosis on Noncontrast MRIY.-M. Chang, A.L. Kuhn, N. Porbandarwala, R. Rojas, V. Ivanovic and R.A. BhadeliaAmerican Journal of Neuroradiology January 2020, 41 (1) 115-121; DOI: https://doi.org/10.3174/ajnr.A6337
Roy, D.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Rubiera, M.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327
Rueda-Lopes, F.C.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Rutland, J.W.
- Adult BrainOpen AccessEmerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future DirectionsJ.W. Rutland, B.N. Delman, C.M. Gill, C. Zhu, R.K. Shrivastava and P. BalchandaniAmerican Journal of Neuroradiology January 2020, 41 (1) 2-9; DOI: https://doi.org/10.3174/ajnr.A6344
S
Sahraian, S.
- You have accessRedundant Neurovascular Imaging: Who Is to Blame and What Is the Value?E. Beheshtian, S. Emamzadehfard, S. Sahraian, R. Jalilianhasanpour and D.M. YousemAmerican Journal of Neuroradiology January 2020, 41 (1) 35-39; DOI: https://doi.org/10.3174/ajnr.A6329
Salmeen, A.K.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Santhanam, P.
- Adult BrainOpen AccessStructural and Volumetric Brain MRI Findings in Mild Traumatic Brain InjuryJ.B. Patel, S.H. Wilson, T.R. Oakes, P. Santhanam and L.K. WeaverAmerican Journal of Neuroradiology January 2020, 41 (1) 92-99; DOI: https://doi.org/10.3174/ajnr.A6346
Schmidbauer, V.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Schmiedeskamp, H.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Schwarz, M.
- FunctionalYou have accessLesion-Specific Language Network Alterations in Temporal Lobe EpilepsyO. Foesleitner, K.-H. Nenning, L. Bartha-Doering, C. Baumgartner, E. Pataraia, D. Moser, M. Schwarz, V. Schmidbauer, J.A. Hainfellner, T. Czech, C. Dorfer, G. Langs, D. Prayer, S. Bonelli and G. KasprianAmerican Journal of Neuroradiology January 2020, 41 (1) 147-154; DOI: https://doi.org/10.3174/ajnr.A6350
Senthilvelan, S.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessVessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya DiseaseA. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand SudhirAmerican Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360
Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.
Settecase, F.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Shankar, J.J.S.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Shibamoto, Y.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Shrivastava, R.K.
- Adult BrainOpen AccessEmerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future DirectionsJ.W. Rutland, B.N. Delman, C.M. Gill, C. Zhu, R.K. Shrivastava and P. BalchandaniAmerican Journal of Neuroradiology January 2020, 41 (1) 2-9; DOI: https://doi.org/10.3174/ajnr.A6344
Shroff, M.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Sivanandan, R.
- LETTEROpen AccessManganese Uptake and Accumulation in the Human BrainV. Blomlie, R. Sivanandan and P. JyngeAmerican Journal of Neuroradiology January 2020, 41 (1) E3; DOI: https://doi.org/10.3174/ajnr.A6347
Slim, M.
- PediatricsYou have accessPredicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with MoyamoyaN. Dlamini, M. Slim, F. Kirkham, M. Shroff, P. Dirks, M. Moharir, D. MacGregor, A. Robertson, G. deVeber and W. LoganAmerican Journal of Neuroradiology January 2020, 41 (1) 160-166; DOI: https://doi.org/10.3174/ajnr.A6324
Sohn, C.-H.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Sorte, D.E.
- Adult BrainYou have accessHigh-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal PatencyA.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. RigamontiAmerican Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
Suh, C.H.
- Head & NeckYou have accessCT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic ReviewC.H. Suh, J.H. Lee, M.K. Lee, S.J. Cho, S.R. Chung, Y.J. Choi and J.H. BaekAmerican Journal of Neuroradiology January 2020, 41 (1) 155-159; DOI: https://doi.org/10.3174/ajnr.A6336
Sylaja, P.N.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessVessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya DiseaseA. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand SudhirAmerican Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360
Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.
T
Takeshima, H.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
Takizawa, M.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Thomalla, G.
- InterventionalYou have accessEmergency Conversion to General Anesthesia Is a Tolerable Risk in Patients Undergoing Mechanical ThrombectomyF. Flottmann, H. Leischner, G. Broocks, T.D. Faizy, A. Aigner, M. Deb-Chatterji, G. Thomalla, J. Krauel, M. Issleib, J. Fiehler and C. BrekenfeldAmerican Journal of Neuroradiology January 2020, 41 (1) 122-127; DOI: https://doi.org/10.3174/ajnr.A6321
Turk, A.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Turner, R.D.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
U
Uchida, Y.
- Adult BrainYou have accessVisualization of Nigrosome 1 from the Viewpoint of Anatomic StructureN. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. ShibamotoAmerican Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
Uetani, H.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
V
van Adel, B.A.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Verdoorn, J.T.
- SpineOpen AccessLateral Decubitus Digital Subtraction Myelography: Tips, Tricks, and PitfallsD.K. Kim, W. Brinjikji, P.P. Morris, F.E. Diehn, V.T. Lehman, G.B. Liebo, J.M. Morris, J.T. Verdoorn, J.K. Cutsforth-Gregory, R.I. Farb, J.C Benson and C.M. CarrAmerican Journal of Neuroradiology January 2020, 41 (1) 21-28; DOI: https://doi.org/10.3174/ajnr.A6368
W
Walsh, J.P.
- EDITOR'S CHOICEAdult BrainYou have accessPrediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal SinusD. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. RohrAmerican Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345
The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.
Wang, H.
- LETTERYou have accessRegarding “the Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, L. Dong, H. Wang and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E2; DOI: https://doi.org/10.3174/ajnr.A6388
- LETTERYou have accessRegarding “The Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, H. Wang, L. Dong and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E1; DOI: https://doi.org/10.3174/ajnr.A6340
Watanabe, T.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
Weaver, L.K.
- Adult BrainOpen AccessStructural and Volumetric Brain MRI Findings in Mild Traumatic Brain InjuryJ.B. Patel, S.H. Wilson, T.R. Oakes, P. Santhanam and L.K. WeaverAmerican Journal of Neuroradiology January 2020, 41 (1) 92-99; DOI: https://doi.org/10.3174/ajnr.A6346
Weill, A.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Werner, H.
- PediatricsYou have accessBrain MR Imaging of Patients with Perinatal Chikungunya Virus InfectionD.G. Corrêa, T. A. L. Freddi, H. Werner, F.P.P.L. Lopes, M.E.L. Moreira, F.C.P. de Almeida Di Maio Ferreira, J.M. de Andrade Lopes, F.C. Rueda-Lopes and L.C.H. da CruzAmerican Journal of Neuroradiology January 2020, 41 (1) 174-177; DOI: https://doi.org/10.3174/ajnr.A6339
Wilson, S.H.
- Adult BrainOpen AccessStructural and Volumetric Brain MRI Findings in Mild Traumatic Brain InjuryJ.B. Patel, S.H. Wilson, T.R. Oakes, P. Santhanam and L.K. WeaverAmerican Journal of Neuroradiology January 2020, 41 (1) 92-99; DOI: https://doi.org/10.3174/ajnr.A6346
Wirth, S.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Won, J.K.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Woo, H.H.
- EDITOR'S CHOICEInterventionalOpen AccessDoes Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results of Embolization of Intracranial Aneurysms at 1 Year: A Randomized TrialJ. Raymond, J. Ghostine, B.A. van Adel, J.J.S. Shankar, D. Iancu, A.P. Mitha, P. Kvamme, R.D. Turner, A. Turk, V. Mendes-Pereira, J.S. Carpenter, S. Boo, A. Evans, H.H. Woo, D. Fiorella, A. Alaraj, D. Roy, A. Weill, P. Lavoie, M. Chagnon, T.N. Nguyen, J.L. Rempel and T.E. DarsautAmerican Journal of Neuroradiology January 2020, 41 (1) 29-34; DOI: https://doi.org/10.3174/ajnr.A6362
Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental group) or 10-caliber coils (control group) was randomized 1:1 using a Web-based platform. The primary efficacy outcome was a major recurrence or a residual aneurysm at follow-up angiography at 12 ± 2 months adjudicated by an independent core lab blinded to the treatment allocation. The trial was stopped after 210 patients were recruited between November 2013 and June 2017 when funding was interrupted. On an intent-to-treat analysis, the primary outcome was reached in 37 patients allocated to 15-caliber coils and 36 patients allocated to 10-caliber coils. Safety and other clinical outcomes were similar. Coiling of aneurysms randomized to 15-caliber coils achieved higher packing densities compared with 10-caliber coils, but this had no impact on the angiographic outcomes at 1 year, which were primarily driven by aneurysm size and initial angiographic results.
Wunderlich, S.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
X
Xu, X.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Y
Yokogami, K.
- Adult BrainYou have accessUsefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic CraniopharyngiomaM. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. HiraiAmerican Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359
Yoo, R.-E.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Young, G.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Yousem, D.M.
- You have accessRedundant Neurovascular Imaging: Who Is to Blame and What Is the Value?E. Beheshtian, S. Emamzadehfard, S. Sahraian, R. Jalilianhasanpour and D.M. YousemAmerican Journal of Neuroradiology January 2020, 41 (1) 35-39; DOI: https://doi.org/10.3174/ajnr.A6329
Yu, K.-H.
- FELLOWS' JOURNAL CLUBAdult BrainOpen AccessDeep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade GliomasW. Han, L. Qin, C. Bay, X. Chen, K.-H. Yu, N. Miskin, A. Li, X. Xu and G. YoungAmerican Journal of Neuroradiology January 2020, 41 (1) 40-48; DOI: https://doi.org/10.3174/ajnr.A6365
Fifty patients with high-grade gliomas from the authors’ hospital and 128 patients with high-grade gliomas from The Cancer Genome Atlas were included in this study. For each patient, the authors calculated 348 hand-crafted radiomics features and 8192 deep features generated by a pretrained convolutional neural network. They then applied feature selection and Elastic Net-Cox modeling to differentiate patients into long- and short-term survivors. In the 50 patients with high-grade gliomas from their institution, the combined feature analysis framework classified the patients into long- and short-term survivor groups with a log-rank test P value <.001. In the 128 patients from The Cancer Genome Atlas, the framework classified patients into long- and short-term survivors with a log-rank test P value of .014. In conclusion, the authors report successful production and initial validation of a deep transfer learning model combining radiomics and deep features to predict overall survival of patients with glioblastoma from postcontrast T1-weighed brain MR imaging.
Yun, T.J.
- Adult BrainOpen AccessDynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic ValueI. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. SohnAmerican Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
Z
Zhang, J.
- LETTERYou have accessRegarding “the Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, L. Dong, H. Wang and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E2; DOI: https://doi.org/10.3174/ajnr.A6388
- LETTERYou have accessRegarding “The Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI”J. Zhang, H. Wang, L. Dong and Y. LiAmerican Journal of Neuroradiology January 2020, 41 (1) E1; DOI: https://doi.org/10.3174/ajnr.A6340
Zhu, C.
- Adult BrainOpen AccessEmerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future DirectionsJ.W. Rutland, B.N. Delman, C.M. Gill, C. Zhu, R.K. Shrivastava and P. BalchandaniAmerican Journal of Neuroradiology January 2020, 41 (1) 2-9; DOI: https://doi.org/10.3174/ajnr.A6344
Zimmer, C.
- Adult BrainYou have accessMicrostructural Integrity of Salvaged Penumbra after Mechanical ThrombectomyM.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. KaesmacherAmerican Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
Zini, A.
- InterventionalYou have accessImaging Triage of Patients with Late-Window (6–24 Hours) Acute Ischemic Stroke: A Comparative Study Using Multiphase CT Angiography versus CT PerfusionM.A. Almekhlafi, W.G. Kunz, R.A. McTaggart, M.V. Jayaraman, M. Najm, S.H. Ahn, E. Fainardi, M. Rubiera, A.V. Khaw, A. Zini, M.D. Hill, A.M. Demchuk, M. Goyal and B.K. MenonAmerican Journal of Neuroradiology January 2020, 41 (1) 129-133; DOI: https://doi.org/10.3174/ajnr.A6327