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Abstract

Gadolinium-DTPA-Enhanced MR Imaging of Spinal Neoplasms: Preliminary Investigation and Comparison with Unenhanced Spin-Echo and STIR Sequences

Gary K. Stimac, Bruce A. Porter, Dana O. Olson, Rebecca Gerlach and Monique Genton
American Journal of Neuroradiology September 1988, 9 (5) 839-846;
Gary K. Stimac
1First Hill Diagnostic Imaging Center, 1001 Boylston Ave., Seattle, WA 98104. Address reprint requests to G. K. Stimac
2Department of Radiology, SB–05, University of Washington, Seattle, WA 98195
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Bruce A. Porter
1First Hill Diagnostic Imaging Center, 1001 Boylston Ave., Seattle, WA 98104. Address reprint requests to G. K. Stimac
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Dana O. Olson
1First Hill Diagnostic Imaging Center, 1001 Boylston Ave., Seattle, WA 98104. Address reprint requests to G. K. Stimac
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Rebecca Gerlach
2Department of Radiology, SB–05, University of Washington, Seattle, WA 98195
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Monique Genton
1First Hill Diagnostic Imaging Center, 1001 Boylston Ave., Seattle, WA 98104. Address reprint requests to G. K. Stimac
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Abstract

Unenhanced T1- and T2-weighted spin-echo, short inversion time inversion recovery (STIR), and gadolinium-DTPA (Gd-DTPA)-enhanced spin-echo and STIR imaging techniques were used in 20 patients as part of a multicenter study to assess the safety and efficacy of Gd-DTPA in spinal imaging. Five patients had normal MR scans. Of those with lesions, both Gd-DTPA-enhanced T1-weighted spin-echo and unenhanced STIR scans improved detection and evaluation of spinal tumors over conventional spin-echo methods, particularly T2-weighted spin echo, by providing higher tissue contrast in shorter imaging times. The Gd-DTPA-enhanced T1-weighted spin-echo scans were most helpful in evaluating intradural tumors, whereas STIR sequences were most effective for extradural tumors and bone metastases. In most cases, Gd-DTPA-enhanced T1-weighted spin-echo scans best delineated tumor margins, and the enhancement was helpful in suggesting a cellular or active nature of the lesions. In some cases, the enhancement resulted in a more homogeneous and thus less abnormal-appearing marrow in vertebrae involved by tumor; therefore, a precontrast T1-weighted spin-echo scan is necessary in all patients who are to be studied with Gd-DTPA.

A combined approach that uses T1-weighted spin-echo, Gd-DTPA-enhanced T1-weighted spin-echo, and STIR images currently appears optimal for MR imaging of spinal neoplasms. T2-weighted spin-echo images add information only in occasional cases.

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American Journal of Neuroradiology
Vol. 9, Issue 5
1 Sep 1988
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Gadolinium-DTPA-Enhanced MR Imaging of Spinal Neoplasms: Preliminary Investigation and Comparison with Unenhanced Spin-Echo and STIR Sequences
Gary K. Stimac, Bruce A. Porter, Dana O. Olson, Rebecca Gerlach, Monique Genton
American Journal of Neuroradiology Sep 1988, 9 (5) 839-846;

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Gadolinium-DTPA-Enhanced MR Imaging of Spinal Neoplasms: Preliminary Investigation and Comparison with Unenhanced Spin-Echo and STIR Sequences
Gary K. Stimac, Bruce A. Porter, Dana O. Olson, Rebecca Gerlach, Monique Genton
American Journal of Neuroradiology Sep 1988, 9 (5) 839-846;
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