We would like to thank Dr. Ambrosetto for his remarks regarding this case report. In our article, we concluded that the transient abnormalities revealed by brain imaging are most likely related to cerebral vasogenic edema owing to abnormal vascular permeability, which causes reversible disruption of the blood-brain barrier.
After reviewing the case, we agree with Dr. Ambrosetto, who pointed out that because the lesions revealed by MR imaging involved mostly the gray matter and did not enhance with contrast material, these most likely represent transient changes secondary to cytotoxic edema.
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