More articles from Brain
- Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence
Sixty-eight patients with treated high-grade gliomas who developed increasing enhancing masses of indeterminate nature underwent DWI and DSC as part of their studies. Pseudoprogression was found in 15% who showed higher ADC as well as lower relative cerebral blood volume when compared with those with recurrent tumors.
- Neurovascular Manifestations in Hereditary Hemorrhagic Telangiectasia: Imaging Features and Genotype-Phenotype Correlations
Imaging features were correlated with genotypes in 75 patients with hereditary hemorrhagic telangiectasia. Sixty-one percent of patients showed small, superficial, capillary malformations without shunting, whereas 43% had true AVMs of small size and low Spetzler-Martin grade. High-flow AVFs were present in 12% of patients and multiple malformations were seen in 44%. No correlation between gene mutations and lesion types was found.
- Evaluation of Virtual Noncontrast Images Obtained from Dual-Energy CTA for Diagnosing Subarachnoid Hemorrhage
A group of 37 patients underwent noncontrast CT and dual-energy CTA for diagnosis of SAH. From the latter, virtual noncontrast images were reconstructed and assessed for SAH. Agreement between true and virtual noncontrast images for diagnosis of SAH was 92%. Thus, virtual noncontrast CT images reliably diagnosed SAH while reducing radiation dose. (See accompanying commentary by Brisman.)
- Imaging the Intracranial Atherosclerotic Vessel Wall Using 7T MRI: Initial Comparison with Histopathology
In this preliminary study, 7T imaging was capable of identifying not only intracranial wall thickening but different plaque components such as foamy macrophages and collagen. Signal heterogeneity was typical of advanced atherosclerotic disease.