Research ArticlePEDIATRICS
Open Access
Development of a Standardized MRI Scoring Tool for CNS Demyelination In Children
L.H. Verhey, H.M. Branson, S. Laughlin, M.M. Shroff, S.M. Benseler, B.M. Feldman, D.L. Streiner, J.G. Sled and B. Banwell
American Journal of Neuroradiology January 2013, DOI: https://doi.org/10.3174/ajnr.A3382
L.H. Verhey
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
H.M. Branson
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
S. Laughlin
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
M.M. Shroff
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
S.M. Benseler
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
B.M. Feldman
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
D.L. Streiner
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
J.G. Sled
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
B. Banwell
From the Program in Neuroscience and Mental Health (L.H.V., B.B.); Division of Pediatric Neuroradiology (H.M.B., S.L., M.M.S.), Department of Diagnostic Imaging; Divisions of Rheumatology (S.M.B., B.M.F.) and Neurology (B.B.), Department of Pediatrics, and Program in Physiology and Experimental Medicine (J.G.S.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychiatry (D.L.S.), Department of Medical Biophysics (J.G.S.), Institute of Medical Science (L.H.V., B.B.), Department of Medical Imaging (H.M.B., S.L., M.M.S.), Institute of Health Policy, Management and Evaluation (S.M.B., B.M.F.); Department of Medicine (B.M.F.); and Dalla Lana School of Public Health (B.M.F.), University of Toronto, Toronto, Ontario, Canada; and Departments of Clinical Epidemiology and Biostatistics (D.L.S.) and Psychiatry and Behavioural Neurosciences (D.L.S.), McMaster University, Hamilton, Ontario, Canada.
Data supplements
Supplemental Online Appendix
Files in this Data Supplement:
- Online Appendix (PDF) -
Online Appendix: see file
Online Table 1: Description of 48 MRI parameters
Online Table 2: Frequency of MRI parameters excluded due to lack of discriminating ability
- Online Appendix (PDF) -
Advertisement
Development of a Standardized MRI Scoring Tool for CNS Demyelination In Children
L.H. Verhey, H.M. Branson, S. Laughlin, M.M. Shroff, S.M. Benseler, B.M. Feldman, D.L. Streiner, J.G. Sled, B. Banwell
American Journal of Neuroradiology Jan 2013, DOI: 10.3174/ajnr.A3382
Jump to section
Related Articles
Cited By...
This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.
- Amy Waldman, Angelo Ghezzi, Amit Bar-Or, Yann Mikaeloff, Marc Tardieu, Brenda BanwellThe Lancet Neurology 2014 13 9
- Giulia Fadda, Robert A Brown, Giulia Longoni, Denise A Castro, Julia O'Mahony, Leonard H Verhey, Helen M Branson, Patrick Waters, Amit Bar-Or, Ruth Ann Marrie, E Ann Yeh, Sridar Narayanan, Douglas L Arnold, Brenda Banwell, Katherine Wambera, Mary B Connolly, Jerome Yager, Jean K Mah, Giullaume Sebire, David Callen, Brandon Meaney, Marie-Emmanuelle Dilenge, Anne Lortie, Daniela Pohl, Asif Doja, Sunita Venkateswaran, Simon Levin, E Athen MacDonald, David Meek, Ellen Wood, David Buckley, Mark Awuku, J Burke Baird, Virender Bhan, Rozie Arnaoutelis, Danusha NandamalavanThe Lancet Child & Adolescent Health 2018 2 3
- Carolin Beuker, Antje Schmidt, Daniel Strunk, Peter B. Sporns, Heinz Wiendl, Sven G. Meuth, Jens MinnerupTherapeutic Advances in Neurological Disorders 2018 11
- Andreas Wegener-Panzer, Robert Cleaveland, Eva-Maria Wendel, Matthias Baumann, Annikki Bertolini, Martin Häusler, Ellen Knierim, Edith Reiter-Fink, Markus Breu, Özcan Sönmez, Adela Della Marina, Renate Peters, Christian Lechner, Martin Piepkorn, Claudia Roll, Romana Höftberger, Frank Leypoldt, Markus Reindl, Kevin RostásyNeurology Neuroimmunology & Neuroinflammation 2020 7 4
- Matthias Baumann, Astrid Grams, Tanja Djurdjevic, Eva-Maria Wendel, Christian Lechner, Bettina Behring, Astrid Blaschek, Katharina Diepold, Astrid Eisenkölbl, Joel Fluss, Michael Karenfort, Johannes Koch, Bahadir Konuşkan, Steffen Leiz, Andreas Merkenschlager, Daniela Pohl, Mareike Schimmel, Charlotte Thiels, Barbara Kornek, Kathrin Schanda, Markus Reindl, Kevin RostásyJournal of Neurology 2018 265 4
- Elizabeth Wells, Yael Hacohen, Amy Waldman, Jan M. Tillema, Ariane Soldatos, Beau Ances, Susanne Benseler, Bibi Bielekova, Russel C. Dale, Josep Dalmau, William Gaillard, Mark Gorman, Benjamin Greenberg, Ann Hyslop, Carlos A. Pardo, Robert C. Tasker, E. Ann Yeh, Amit Bar-Or, Sean Pittock, Adeline Vanderver, Brenda Banwell, Jessica Carpenter, Irene Cortese, Nathan Dean, Racquel Farias-Moeller, William Gallentine, Carol Glaser, Raphaela Goldbach-Mansky, Ilana Kahn, Bennett Lavenstein, William McClintock, William McDow, Jennifer Murphy, Avindra Nath, Roger Packer, Tova Ronis, David Schleyer, Stephanie Schleyer, Peter Shibuya, Ursula Utz, Gilbert Vezina, David WesselNature Reviews Neurology 2018 14 7
- M. Twilt, S. M. BenselerRheumatology 2014 53 8
- Christine Till, Austin Noguera, Leonard H. Verhey, Julia O’Mahony, E. Ann Yeh, Jean K. Mah, Katia J. Sinopoli, Brian L. Brooks, Berengere Aubert-Broche, D. Louis Collins, Sridar Narayanan, Douglas L. Arnold, Brenda L. BanwellJournal of the International Neuropsychological Society 2016 22 10
- Min Zhang, Xiaonan Du, Shuizhen Zhou, Gang Pan, Jin Shen, Wenhui Li, Lifei Yu, Yuanfeng Zhou, Yunjian Zhang, Yi Wang, Linmei ZhangJournal of Clinical Neuroscience 2021 94
More in this TOC Section
Similar Articles
Advertisement