Research ArticleADULT BRAIN
Imaging Biomarkers for Adult Medulloblastomas: Genetic Entities May Be Identified by Their MR Imaging Radiophenotype
V.C. Keil, M. Warmuth-Metz, C. Reh, S.J. Enkirch, C. Reinert, D. Beier, D.T.W. Jones, T. Pietsch, H.H. Schild, E. Hattingen and P. Hau
American Journal of Neuroradiology August 2017, DOI: https://doi.org/10.3174/ajnr.A5313
V.C. Keil
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
M. Warmuth-Metz
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
C. Reh
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
S.J. Enkirch
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
C. Reinert
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
D. Beier
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
D.T.W. Jones
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
T. Pietsch
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
H.H. Schild
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
E. Hattingen
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
P. Hau
From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
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- Published online August 10, 2017.
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© 2017 American Society of Neuroradiology
Author Information
- V.C. Keil,
- M. Warmuth-Metz,
- C. Reh,
- S.J. Enkirch,
- C. Reinert,
- D. Beier,
- D.T.W. Jones,
- T. Pietsch,
- H.H. Schild,
- E. Hattingen and
- P. Hau
- From the Department of Radiology and Neuroradiology (V.C.K., C.R., S.J.E., H.H.S., E.H.), University Hospital Bonn, Bonn, Germany; Institute for Diagnostic and Interventional Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center of the German Society for Neuropathology and Neuroanatomy, Bonn, Germany; Wilhelm Sander-Therapieeinheit NeuroOnkologie (C.R., P.H.) and Department of Neurology (C.R., P.H.), University Hospital Regensburg, Regensburg, Germany; Department of Neurology (D.B.), University Hospital Odense and Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Neurology (D.B.), University of Regensburg, Regensburg, Germany; and Deutsches Krebsforschungszentrum (D.T.W.J.), Division of Pediatric Neurooncology, Heidelberg, Germany.
- Please address correspondence to Vera C. Keil, MD, Universitätsklinik Bonn, Radiologische Klinik, Sigmund-Freud-Str 25, D-53127 Bonn, Germany; e-mail: vera.keil{at}ukbonn.de
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Imaging Biomarkers for Adult Medulloblastomas: Genetic Entities May Be Identified by Their MR Imaging Radiophenotype
V.C. Keil, M. Warmuth-Metz, C. Reh, S.J. Enkirch, C. Reinert, D. Beier, D.T.W. Jones, T. Pietsch, H.H. Schild, E. Hattingen, P. Hau
American Journal of Neuroradiology Aug 2017, DOI: 10.3174/ajnr.A5313
Imaging Biomarkers for Adult Medulloblastomas: Genetic Entities May Be Identified by Their MR Imaging Radiophenotype
V.C. Keil, M. Warmuth-Metz, C. Reh, S.J. Enkirch, C. Reinert, D. Beier, D.T.W. Jones, T. Pietsch, H.H. Schild, E. Hattingen, P. Hau
American Journal of Neuroradiology Aug 2017, DOI: 10.3174/ajnr.A5313
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