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Research ArticlePEDIATRICS
Open Access

Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium

S. Vajapeyam, D. Brown, C. Billups, Z. Patay, G. Vezina, M.S. Shiroishi, M. Law, P. Baxter, A. Onar-Thomas, J.R. Fangusaro, I.J. Dunkel and T.Y. Poussaint
American Journal of Neuroradiology April 2020, DOI: https://doi.org/10.3174/ajnr.A6499
S. Vajapeyam
aFrom the Radiology (S.V., T.Y.P.), Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts
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  • ORCID record for S. Vajapeyam
D. Brown
bDF/HCC Tumor Imaging Metrics Core (D.B.), Massachusetts General Hospital, Boston, Massachusetts
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  • ORCID record for D. Brown
C. Billups
cBiostatistics (C.B., A.O.-T.)
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  • ORCID record for C. Billups
Z. Patay
dDiagnostic Imaging (Z.P.), St. Jude Children’s Research Hospital, Memphis, Tennessee
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  • ORCID record for Z. Patay
G. Vezina
eRadiology (G.V.), Children’s National Medical Center, Washington, DC
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  • ORCID record for G. Vezina
M.S. Shiroishi
fRadiology (M.S.S.), Keck Medical Center of USC, Los Angeles, California
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  • ORCID record for M.S. Shiroishi
M. Law
gNeuroscience (M.L.), Monash University, Melbourne, Australia
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P. Baxter
hCancer and Hematology Center (P.B.), Texas Children’s Hospital, Houston, Texas
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  • ORCID record for P. Baxter
A. Onar-Thomas
cBiostatistics (C.B., A.O.-T.)
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J.R. Fangusaro
iAflac Cancer and Blood Disorders Center (J.R.F.), Children’s Healthcare of Atlanta, Atlanta, Georgia
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I.J. Dunkel
jPediatrics (I.J.D.), Memorial Sloan Kettering Cancer Center, New York, New York.
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T.Y. Poussaint
aFrom the Radiology (S.V., T.Y.P.), Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts
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Article Information

DOI 
https://doi.org/10.3174/ajnr.A6499
PubMed 
32241771

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received November 21, 2019
  • Accepted after revision February 10, 2020
  • Published online April 2, 2020.

Article Versions

  • You are currently viewing a Latest version of this article (April 2, 2020 - 09:05).
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Copyright & Usage 
© 2020 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. S. Vajapeyama,
  2. D. Brownb,
  3. C. Billupsc,
  4. Z. Patayd,
  5. G. Vezinae,
  6. M.S. Shiroishif,
  7. M. Lawg,
  8. P. Baxterh,
  9. A. Onar-Thomasc,
  10. J.R. Fangusaroi,
  11. I.J. Dunkelj and
  12. T.Y. Poussainta
  1. aFrom the Radiology (S.V., T.Y.P.), Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts
  2. bDF/HCC Tumor Imaging Metrics Core (D.B.), Massachusetts General Hospital, Boston, Massachusetts
  3. cBiostatistics (C.B., A.O.-T.)
  4. dDiagnostic Imaging (Z.P.), St. Jude Children’s Research Hospital, Memphis, Tennessee
  5. eRadiology (G.V.), Children’s National Medical Center, Washington, DC
  6. fRadiology (M.S.S.), Keck Medical Center of USC, Los Angeles, California
  7. gNeuroscience (M.L.), Monash University, Melbourne, Australia
  8. hCancer and Hematology Center (P.B.), Texas Children’s Hospital, Houston, Texas
  9. iAflac Cancer and Blood Disorders Center (J.R.F.), Children’s Healthcare of Atlanta, Atlanta, Georgia
  10. jPediatrics (I.J.D.), Memorial Sloan Kettering Cancer Center, New York, New York.
  1. Please address correspondence to Sridhar Vajapeyam, PhD, Boston Children’s Hospital and Harvard Medical School, Department of Radiology, 300 Longwood Ave, Boston, MA 02115; e-mail: sridhar.vajapeyam{at}childrens.harvard.edu
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Funding

  • American Lebanese Syrian Associated Charities

  • Pediatric Brain Tumor Consortium Foundation

  • National Cancer Institute

    P30 CA008748; UM1CA081457
  • Pediatric Brain Tumor Foundation

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Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium
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Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium
S. Vajapeyam, D. Brown, C. Billups, Z. Patay, G. Vezina, M.S. Shiroishi, M. Law, P. Baxter, A. Onar-Thomas, J.R. Fangusaro, I.J. Dunkel, T.Y. Poussaint
American Journal of Neuroradiology Apr 2020, DOI: 10.3174/ajnr.A6499

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Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium
S. Vajapeyam, D. Brown, C. Billups, Z. Patay, G. Vezina, M.S. Shiroishi, M. Law, P. Baxter, A. Onar-Thomas, J.R. Fangusaro, I.J. Dunkel, T.Y. Poussaint
American Journal of Neuroradiology Apr 2020, DOI: 10.3174/ajnr.A6499
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