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Research ArticleSPINE
Open Access

COVID-19-Associated Myelitis Involving the Dorsal and Lateral White Matter Tracts: A Case Series and Review of the Literature

H.Y. Huang, L.M. Shah, J.S. McNally, T. Sant, T.A. Hutchins, E.D. Goldstein and M.E. Peckham
American Journal of Neuroradiology August 2021, DOI: https://doi.org/10.3174/ajnr.A7256
H.Y. Huang
aFrom the Departments of Neurology (H.Y.H., E.D.G.)
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L.M. Shah
bRadiology and Imaging Sciences (L.M.S., J.S.M., T.A.H., M.E.P.)
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J.S. McNally
bRadiology and Imaging Sciences (L.M.S., J.S.M., T.A.H., M.E.P.)
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T. Sant
cSchool of Medicine (T.S.), University of Utah, Salt Lake City, Utah
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T.A. Hutchins
bRadiology and Imaging Sciences (L.M.S., J.S.M., T.A.H., M.E.P.)
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  • ORCID record for T.A. Hutchins
E.D. Goldstein
aFrom the Departments of Neurology (H.Y.H., E.D.G.)
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M.E. Peckham
bRadiology and Imaging Sciences (L.M.S., J.S.M., T.A.H., M.E.P.)
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  • ORCID record for M.E. Peckham
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Article Figures & Data

Figures

  • FIG 1.
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    FIG 1.

    Axial T2 (A), and T1 postcontrast (B) images demonstrate T2 hyperintensity involving the posterior columns and patchy enhancement predominantly in the posterior and lateral columns (arrow pointing to posterior column in A, and arrow to lateral column in B). Sagittal T2 (C) and postcontrast T1 (D) images demonstrate corresponding signal changes (arrows).

  • FIG 2.
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    FIG 2.

    Axial T2 (A) and diffusion-weighted (B) images demonstrate T2 hyperintensity involving the posterior (gray arrow) and lateral columns (white arrows) with corresponding DWI hyperintensity and ADC hypointensity (C) confirming restriction (white arrows). Findings were less conspicuous on sagittal T2 (D) and postcontrast T1 (E) images, with only faint signal changes present (white arrows).

  • FIG 3.
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    FIG 3.

    Axial T2 (A) and T1 postcontrast (B) images demonstrate T2 hyperintensity involving the posterior columns (gray arrow), with faint involvement of the lateral columns (white arrows, A). There was corresponding scattered patchy enhancement in these regions (gray arrow, B). T2 hyperintensity and expansion of the upper thoracic cord was well-demonstrated on sagittal views (white arrow, C). Brain MR imaging shows T2/FLAIR hyperintensity and corresponding enhancement surrounding the fourth ventricle (white arrows, D and E).

  • FIG 4.
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    FIG 4.

    Axial T2 image through the thoracic cord demonstrates T2 hyperintensity involving the posterior columns (white arrow). Subtle hyperintensity could be seen in this region on sagittal T2 images (white arrow).

  • FIG 5.
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    FIG 5.

    Axial T2 (A) and T1 postcontrast (B) images through the thoracic cord demonstrate T2 hyperintensity involving the posterior columns (white arrow), with no corresponding enhancement. A sagittal T2 image in the cervical spine (C) demonstrates hyperintensity along the dorsal aspect of the cord (white arrow).

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COVID-19-Associated Myelitis Involving the Dorsal and Lateral White Matter Tracts: A Case Series and Review of the Literature
H.Y. Huang, L.M. Shah, J.S. McNally, T. Sant, T.A. Hutchins, E.D. Goldstein, M.E. Peckham
American Journal of Neuroradiology Aug 2021, DOI: 10.3174/ajnr.A7256

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COVID-19-Associated Myelitis Involving the Dorsal and Lateral White Matter Tracts: A Case Series and Review of the Literature
H.Y. Huang, L.M. Shah, J.S. McNally, T. Sant, T.A. Hutchins, E.D. Goldstein, M.E. Peckham
American Journal of Neuroradiology Aug 2021, DOI: 10.3174/ajnr.A7256
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