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Research ArticlePEDIATRICS
Open Access

A Uniform Description of Perioperative Brain MRI Findings in Infants with Severe Congenital Heart Disease: Results of a European Collaboration

R. Stegeman, M. Feldmann, N.H.P. Claessens, N.J.G. Jansen, J.M.P.J. Breur, L.S. de Vries, T. Logeswaran, B. Reich, W. Knirsch, R. Kottke, C. Hagmann, B. Latal, J. Simpson, K. Pushparajah, A.F. Bonthrone, C.J. Kelly, S. Arulkumaran, M.A. Rutherford, S.J. Counsell, M.J.N.L. Benders and the European Association Brain in Congenital Heart Disease Consortium
American Journal of Neuroradiology October 2021, DOI: https://doi.org/10.3174/ajnr.A7328
R. Stegeman
aFrom the Departments of Neonatology (R.S., N.H.P.C., L.S.d.V., M.J.N.L.B.)
bPediatric Intensive Care (R.S., N.H.P.C., N.J.G.J.)
cPediatric Cardiology (R.S., N.H.P.C., J.M.P.J.B.), Wilhelmina Children’s Hospital, UMC Utrecht, Utrecht, the Netherlands
dUtrecht Brain Center (R.S., L.S.d.V., M.J.N.L.B.), UMC Utrecht, Utrecht University, Utrecht, the Netherlands
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M. Feldmann
eChild Development Center (M.F., B.L.)
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  • ORCID record for M. Feldmann
N.H.P. Claessens
aFrom the Departments of Neonatology (R.S., N.H.P.C., L.S.d.V., M.J.N.L.B.)
bPediatric Intensive Care (R.S., N.H.P.C., N.J.G.J.)
cPediatric Cardiology (R.S., N.H.P.C., J.M.P.J.B.), Wilhelmina Children’s Hospital, UMC Utrecht, Utrecht, the Netherlands
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N.J.G. Jansen
bPediatric Intensive Care (R.S., N.H.P.C., N.J.G.J.)
iDepartment of Pediatrics (N.J.G.J.), Beatrix Children’s Hospital, UMC Groningen, Groningen, the Netherlands
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  • ORCID record for N.J.G. Jansen
J.M.P.J. Breur
cPediatric Cardiology (R.S., N.H.P.C., J.M.P.J.B.), Wilhelmina Children’s Hospital, UMC Utrecht, Utrecht, the Netherlands
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L.S. de Vries
aFrom the Departments of Neonatology (R.S., N.H.P.C., L.S.d.V., M.J.N.L.B.)
dUtrecht Brain Center (R.S., L.S.d.V., M.J.N.L.B.), UMC Utrecht, Utrecht University, Utrecht, the Netherlands
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T. Logeswaran
jPediatric Heart Center (T.L., B.R.), University Hospital Giessen, Justus-Liebig-University Giessen, Giessen, Germany
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  • ORCID record for T. Logeswaran
B. Reich
jPediatric Heart Center (T.L., B.R.), University Hospital Giessen, Justus-Liebig-University Giessen, Giessen, Germany
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  • ORCID record for B. Reich
W. Knirsch
fDivision of Pediatric Cardiology (W.K.), Pediatric Heart Center
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R. Kottke
gDepartment of Diagnostic Imaging (R.K.)
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C. Hagmann
hDepartment of Neonatology and Pediatric Intensive Care (C.H.), University Children’s Hospital Zurich, Zurich, Switzerland
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B. Latal
eChild Development Center (M.F., B.L.)
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J. Simpson
kDepartment of Pediatric Cardiology (J.S., K.P.), Evelina Children’s Hospital London, London, UK
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K. Pushparajah
kDepartment of Pediatric Cardiology (J.S., K.P.), Evelina Children’s Hospital London, London, UK
lCentre for the Developing Brain (K.P., A.F.B., C.J.K., S.A., M.A.R., S.J.C.), School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK
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A.F. Bonthrone
lCentre for the Developing Brain (K.P., A.F.B., C.J.K., S.A., M.A.R., S.J.C.), School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK
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C.J. Kelly
lCentre for the Developing Brain (K.P., A.F.B., C.J.K., S.A., M.A.R., S.J.C.), School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK
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S. Arulkumaran
lCentre for the Developing Brain (K.P., A.F.B., C.J.K., S.A., M.A.R., S.J.C.), School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK
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M.A. Rutherford
lCentre for the Developing Brain (K.P., A.F.B., C.J.K., S.A., M.A.R., S.J.C.), School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK
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S.J. Counsell
lCentre for the Developing Brain (K.P., A.F.B., C.J.K., S.A., M.A.R., S.J.C.), School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK
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M.J.N.L. Benders
aFrom the Departments of Neonatology (R.S., N.H.P.C., L.S.d.V., M.J.N.L.B.)
dUtrecht Brain Center (R.S., L.S.d.V., M.J.N.L.B.), UMC Utrecht, Utrecht University, Utrecht, the Netherlands
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    Proportion of infants with CHD with any kind of brain lesions. Any lesion included white matter injury, arterial ischemic stroke, hypoxic-ischemic watershed injury, intraparenchymal cerebral hemorrhage, cerebellar hemorrhage, intraventricular hemorrhage, and cerebral sinovenous thrombosis. Subdural hemorrhage was recorded but was not considered brain injury, being extra-axial and given its frequent occurrence in the healthy neonatal population.

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A Uniform Description of Perioperative Brain MRI Findings in Infants with Severe Congenital Heart Disease: Results of a European Collaboration
R. Stegeman, M. Feldmann, N.H.P. Claessens, N.J.G. Jansen, J.M.P.J. Breur, L.S. de Vries, T. Logeswaran, B. Reich, W. Knirsch, R. Kottke, C. Hagmann, B. Latal, J. Simpson, K. Pushparajah, A.F. Bonthrone, C.J. Kelly, S. Arulkumaran, M.A. Rutherford, S.J. Counsell, M.J.N.L. Benders, the European Association Brain in Congenital Heart Disease Consortium
American Journal of Neuroradiology Oct 2021, DOI: 10.3174/ajnr.A7328

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A Uniform Description of Perioperative Brain MRI Findings in Infants with Severe Congenital Heart Disease: Results of a European Collaboration
R. Stegeman, M. Feldmann, N.H.P. Claessens, N.J.G. Jansen, J.M.P.J. Breur, L.S. de Vries, T. Logeswaran, B. Reich, W. Knirsch, R. Kottke, C. Hagmann, B. Latal, J. Simpson, K. Pushparajah, A.F. Bonthrone, C.J. Kelly, S. Arulkumaran, M.A. Rutherford, S.J. Counsell, M.J.N.L. Benders, the European Association Brain in Congenital Heart Disease Consortium
American Journal of Neuroradiology Oct 2021, DOI: 10.3174/ajnr.A7328
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