Section Editor: Sandy Cheng-Yu Chen, M.D.
Taipei Medical University Hospital, Taipei, Taiwan
Figure Caption
The diagnosis of childhood multiple sclerosis is based on disease presentation that disseminates in space and time and excludes other neurological disorders that can clinically and radiologically mimic multiple sclerosis. The typical imaging features are involvement of callososeptal interface in the form of irregularity and hyperintensity as seen on sagittal FLAIR (yellow arrows in A) and hyperintensities perpendicular to long axis of corpus callosum, called Dawson’s fingers (green arrows in A and C) . Infratentorial T2 hyperintensity (yellow arrow in B), periventricular, and subcortical hyperintensities are also seen (C). After gadolinium, the lesions may or may not show enhancement(D), depending on the age of the lesions.