Abstract
Purpose
This study investigates retrospectively the clinical, neuroradiological, pathological and surgical evidence verifying the infundibulo-tuberal topography for craniopharyngiomas (CPs). Infundibulo-tuberal CPs represent a surgical challenge due to their close anatomical relationships with the hypothalamus. An accurate definition of this topographical category is essential in order to prevent any undue injury to vital diencephalic centres.
Methods
A systematic review of all scientific reports involving pathological, neuroradiological or surgical descriptions of either well-described individual cases or large series of CPs published in official journals and text books from 1892 to 2011 was carried out. A total of 1,232 documents providing pathological, surgical and/or neuroradiological evidence for the infundibulo-tuberal or hypothalamic location of CPs were finally analysed in this study.
Findings
For a total of 3,571 CPs included in 67 pathological, surgical or neuroradiological series, 1,494 CPs (42%) were classified as infundibulo-tuberal lesions. This topography was proved in the autopsy of 122 non-operated cases. The crucial morphological finding characterizing the tubero-infundibular topography was the replacement of the third ventricle floor by a lesion with a predominant intraventricular growth. This type of CP usually presents a circumferential band of tight adherence to the third ventricle floor remnants, formed by a functionless layer of rective gliosis of a variable thickness. After complete surgical removal of an infundibulo-tuberal CP, a wide defect or breach at the floor of the third ventricle is regularly observed both in the surgical field and on postoperative magnetic resonance imaging studies.
Conclusions
Infundibulo-tuberal CPs represent a major topographical category of lesions with a primary subpial development at the floor of the third ventricle. These lesions expand within the hypothalamus itself and subsequently occupy the third ventricle; consequently, they can be classified as not strictly intraventricular CPs. A tight attachment to the hypothalamus and remnants of the third ventricle floor is the pathological landmark of infundibulo-tuberal CPs.
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References
Adamson TE, Wiestler OD, Kleihues P, Yargil MG (1990) Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J Neurosurg 73:12–17
Aguado LI, Schoebitz K, Rodriguez EM (1981) Intercellular channels in the pars tuberalis of the rat hypophysis and their relationship to the subarachnoid space. Cell Tissue Res 218:345–354
Aiba T, Yamada S (1980) Surgery of craniopharyngiomas in adults. Neurol Med Chir (Tokyo) 20:439–451
Alpers BJ (1940) Personality and emotional disorders associated with hypothalamic lesions. Psychosomatic Med 2:286–303
Allegranza A (1995) Neuropathology of craniopharyngioma. In: Broggi G (ed) Craniopharyngioma. Surgical treatment. Milano, Italy, Springer, pp 1–5
Apuzzo MLJ, Zee CS, Breeze RE (1987) Anterior and mid-thirdventricular lesions: surgical overview. In: Apuzzo MLJ (ed) Surgery of the third ventricle. Williams and Wilkins, Baltimore, pp 495–542
Armstrong CN (1924) Three cases of supra-pituitary tumour presenting Frölich syndrome. Brain 45:113–125
Asa SL, Kovacs K, Bilbao JM (1983) The pars tuberalis of the human pituitary. A histologic, immunohistochemical, ultrastructural and immunoelectron microscopic analysis. Virchows Arch 399:49–59
Attwell WJ (1918) The development of the hypophysis cerebri of the rabbit (Lepus Cunilicus L.). Am J Anat 24:271–337
Attwell WJ (1926) The development of the hypophysis cerebri in man, with special reference to the pars tuberalis. Am J Anat 37:159–193
Babinsky MJ (1900) Tumeur du corps pituitaire sans acromégalie et avec arrèt de développement des organs génitaux. Rev Neurol 8:531–533
Bailey P (1924) Concerning the cerebellar symptoms produced by suprasellar tumors. Arch Neurol Psychiatr 11:137–150
Bailey P (1933) Craniopharyngiomas. Syndrome of the Hypothalamus. In: Bailey P (ed) Intracranial Tumors. Charles H Thomas, Springfield, pp 113–137
Bailey P, Buchanan DN, Bucy PC (1939) Intracranial tumors of infancy and childhood. University of Chicago Press, Chicago, pp 349–375
Beckmann JW, Kubie LS (1929) A clinical study of twenty-one cases of tumors of the hypophyseal stalk. Brain 52:127–170
Biggart JH, Dott NM (1936) Pituitary tumors: their classification and treatment. Br Med J 2(3961):1153–1155; 2(3962):1206–1208
Biggart JH (1961) Pathology of the nervous system. A student’s introduction, 3rd edn. Williams and Wilkins, Baltimore, pp 322–327
Blackburn IW (1903) Intracranial tumors among the insane. A study of twenty-nine intracranial tumors found in sixteen hundred and forty-two autopsies in cases of mental disease. Government Printing Office, Washington
Burger PC (1994) Craniopharyngiomas. In: Atlas of tumor pathology, 3rd series, fascicle 10. Tumors of the central nervous system. Armed Forces Institute of Pathology,Washington, pp 349–354
Burger PC (2002) Craniopharyngiomas. In: Burger PC, Scheithauer B, Vogel FS (eds) Surgical pathology of the nervous system and its coverings, 4th edn. Churchill Livingstone, New York, pp 475–482
Cairns H (1952) Disturbances of consciousness with lesions of the brain-stem and diencephalon. Brain 75:109–146
Carmel W (1980) Surgical syndromes of the hypothalamus. Clin Neurosurg 27:133–159
Carmichael HT (1931) Squamous epithelial rests in the hypophysis cerebri. Arch Neurol Psychiatr 26:966–975
Choux M, Lena G, Genitori L (1991) Le craniopharyngiome de l’enfant. Neurochirurgie 37(Suppl 1):7–10
Choux M, Lena G (1998) Craniopharyngioma. In: Apuzzo MLJ (ed) Surgery of the third ventricle, 2nd edn. Williams and Wilkins, Baltimore, pp 1143–1181
Chung W-Y, Pan DH-C, Shiau C-Y, Guo W-Y, Wang L-W (2000) Gamma Knife radiosurgery for craniopharyngiomas. J Neurosurg 93(Suppl 3):47–56
Ciric IS (1987) Regional embryology. In: Apuzzo MLJ (ed) Surgery of the third ventricle. Williams and Wilkins, Baltimore, pp 167–174
Ciric IS, Cozzens JW (1980) Craniopharyngiomas: transsphenoidal method of approach—for the virtuoso only? Clin Neurosurg 27:169–187
Clar HE (1985) Disturbances of the hypothalamic thermoregulation. Acta Neurochir 75:106–112
Cohen-Gadol AA, Spencer DD (2007) The legacy of Harvey Cushing: profiles of patient care. New York, Thieme, pp 1–93
Cohen-Gadol AA, Geryk B, Binder DK, Tubbs RS (2009) Conquering the third ventricular chamber. J Neurosurg 111:590–599
Critchley M, Ironside RN (1926) The pituitary adamantinomata. Brain 49:437–481
Crotty TB, Scheithauer BW, Young WF Jr, Davis DH, Shaw EG, Miller GM et al (1995) Papillary craniopharyngioma: a clinicopathological study of 48 cases. J Neurosurg 83:206–214
Cuneo HM, Rand CW (1952) Brain tumors of childhood. Charles C Thomas Springfield, pp 43–57
Cushing H (1912) The pituitary body and its disorders. JB Lippincott, Philadelphia, pp 289–291
Cushing H (1922) Les syndromes hypophysaires au point de vue chirurgical. Rev Neurol 38:779–808
Cushing H (1930) The chiasmal syndrome of primary optic atrophy and bitemporal field defects in adults with a normal sella turcica. Arch Ophthalmol 3:505–551
Cushing H (1932) Intracranial tumors. Notes upon a series of two thousand verified cases with surgical mortality percentages pertaining thereto. Charles C. Thomas, Springfield, pp 93–98
Cushing H (1932) Papers relating to the pituitary body. Hypothalamus and parasympathetic nervous system. Charles C Thomas, Springfield, pp 43–56
Davison C, Demuth EL (1946) Disturbances in sleep mechanism. A clinicopathologic study Arch Neurol Psychiatry 55:111–125
de Divitiis E, Cappabianca P, Cavallo LM, Esposito F, de Divitiis O, Messina A (2007) Extended endoscopic transsphenoidal approach for extrasellar craniopharyngiomas. Neurosurgery 61 (ONS Suppl 2):ONS219–ONS228
De Vile CJ, Grant DB, Kendall BE, Neville BGR, Stanhope R, Watkins KE, Hayward RD (1996) Management of childhood craniopharyngioma: can the morbidity of radical surgery be predicted? J Neurosurg 85:73–81
De Vile CJ, Grant DB, Hayward RD, Kendall BE, Neville BGR, Stanhope R (1996) Obesity in childhood craniopharyngioma: relation to post-operative hypothalamic damage shown by magnetic resonance imaging. J Clin Endocrinol 81:2734–2737
Del Vivo RE, Armenise B, Regli F (1962) Varietà formali e problema istogenetici del craniofaringioma. Studio istopatologico su 30 observazioni. Arch de Vecchi Anat Pathol 38:1–79
Dialti G (1910) Patologia e Chirurgia della Ipofisi. Siena, Tipografia Editrice S. Bernardino, pp 20–24
Dott NM (1938) Surgical aspects of the hypothalamus. In: Clarke WE, Beattie J, Riddoch G, Dott NM (eds) the hypothalamus. Oliver and Boyd, Edinburgh, pp 131–199
Duffy WC (1920) Hypophyseal duct tumors. Ann Surg 72(537–555):725–757
Eldevik OP, Blaivas M, Gabrielsen TO, Hald JK, Chandler WF (1996) Craniopharyngioma: radiologic and histologic findings and recurrence. AJNR Am J Neuroradiol 17:1427–1439
Erdheim J (1904) (1904) Über Hypophysengangsgeschwulste und Hirmcholesteatome. Sitzungsb Kais Akad Wissen Math Naturw Klin 113:537–726
Frank G, Pasquini E, Doglietto F, Mazzatenta D, Sciaretta V, Farneti G, Calbucci F (2006) The endoscopic extended transsphenoidal approach for craniopharyngiomas. Oper Neurosurg 59:75–83
Frazier CH, Alpers BJ (1931) Adamantinoma of the craniopharyngeal duct. Arch Neurol Psychiatr 26:905–965
Frazier CH (1936) A review, clinical and pathological, of parahypophyseal lesions. Surg Gynec Obst 62:1–33
Fukushima T, Yamakawa K (1989) Surgical management of craniopharyngiomas. Comparison of results by different operative approaches. In: Holtzman RNN, Stein BM (eds) Surgery of the diencephalon. Plenum, New York, pp 259–269
Fulton JF, Bailey P (1929) Tumors in the region of the third ventricle: their diagnosis and relation to pathological sleep. J Nerv Mental Dis 69:1–25, 145–164, 261–277
Ghatak NR, Hirano A, Zimmerman HM (1978) Ultrastructure of a craniopharyngioma. Cancer 27:425–430
Globus JH, Gang KM (1945) Craniopharyngeoma and suprasellar adamantinoma. J Mt Sinai Hosp 12:220–276
Goldberg GM, Eshbaugh DE (1960) Squamous cell nests of the pituitary gland as related to the origin of craniopharyngiomas. Arch Pathol 70:293–299
Goldstein K (1928) Kasuistiche Mitteilungen zur Klinik und pathologischen anatomie der nervenkrankheiten. I. Cohn H, Goldstein K: Zur klinik und pathologie hypophysärer erkrankungen, im besonderen der tumoren der hypophysengegend. Deutsch Zeitschr Nervenheilkund 103:225–274
Grekhov VV (1959) Topography of craniopharyngioma. Vopr Neirokhir 23:12–17
Grekhov VV (1959) Structure of parenchyma of craniopharyngiomas. Vopr Neirokhir 23:1–5
Harbitz F (1935) Tumors arising from the hypophysial duct, and other neoplasms related thereto. Chordomas Acta Pathol Microbiol Scand 12:38–78
Harrison MJ, Morgello S, Post KD (1994) Epithelial cystic lesions of the sellar and parasellar region: a continuum of ectodermal derivatives? J Neurosurg 80:1018–1025
Hazlerigg DG (2001) What is the role of melatonin within the anterior pituitary? J Endocrinol 170:493–501
Henke F, Lubarsch O (1926) Handbuch der Speziellen Pathologischen Anatomie und Histologie, Bd 8: Drusen mit innerer secretion. Springer, Berlin
Hirsch O, Hamlin H (1959) Symptomatology and treatment of the hypophyseal duct tumors (craniopharyngiomas). Confin Neurol 19:153–219
Hoffman HJ, Hendrick EB, Humphreys RP, Buncic JR, Armstrong DL, Jenkin RDT (1977) Management of craniopharyngioma in children. J Neurosurg 47:218–227
Hoffman HJ, De Silva M, Humphreys RP, Drake JM, Smith ML, Blaser SI (1992) Agressive surgical management of craniopharyngiomas in children. J Neurosurg 76:47–52
Hunter IJ (1955) Squamous metaplasia of cells of the anterior pituitary gland. J Path Bact 69:141–145
Ingraham FD, Scott HW (1946) Craniopharyngiomas in children. J Pediatrics 29:95–116
Kahn EA (1955) Tumors of the sellar region. In: Kahn EA, Bassett RC, Schneider RC, Crosby EC (eds) Correlative neurosurgery. Charles C Thomas, Springfield, pp 174–181
Kahn EA, Gosch HH, Seeger J, Hicks JF (1973) Forty-five years experience with craniopharyngiomas. Surg Neurol 1:5–12
Kassam AB, Gardner PA, Snyderman CH, Carrau RL, Mintz AH, Prevedello DM (2008) Expanded endonasal approach, a fully endoscopic transnasal approach for the resection of midline suprasellar craniopharyngiomas: a new classification based on the infundibulum. J Neurosurg 108:715–728
Kaufmann E (1929) Lehrbuch der Pathologischen Anatomie. Translated by SP Reinmann SP, vol III. Blackiston, Philadelphia
Kim EH, Ahn JY, Kim SH (2011) (2011) Technique and outcome of endoscopy-assisted microscopic extended transsphenoidal surgery for suprasellar craniopharyngiomas. J Neurosurg 114:1338–1349
King TT (1979) Removal of intraventricular craniopharyngiomas through the lamina terminalis. Acta Neurochir (Wien) 45:277–286
Kobayashi T, Kageyama N, Yoshida J, Shibuya N, Yonezawa T (1981) Pathological and clinical basis of the indications for treatment of craniopharyngiomas. Neurol Med Chir (Tokyo) 21:39–47
Kobayashi T, Tanaka T, Kida Y (1994) Stereotactic gamma radiosurgery of craniopharyngiomas. Pediatr Neurosurg 21(Suppl 1):69–74
Konovalov AN (1981) Operative management of craniopharyngiomas. Adv Tech Stand Neurosurg 8:281–318
Konovalov AN, Goralyshev SK (1992) Surgical treatment of anterior third ventricle tumours. Acta Neurochir 118:33–39
Konovalov AN (1993) Craniopharyngioma: complications and their avoidance. In: Apuzzo MLJ (ed) Brain surgery: complications avoidance and management. Churchill Livingstone, New York, pp 362–368
Konovalov AN (1998) Technique and strategies of direct surgical management of craniopharyngiomas. In: Apuzzo MLJ (ed) Surgery of the third ventricle, 2nd edn. Williams and Wilkins, Baltimore, pp 1133–1142
Kornienko VN, Pronin IN (2009) Diagnostic neuroradiology. Springer, Berlin, pp 558–573
Kubota T, Yamamoto S, Kohno H, Ito H, Hayashi M (1980) Operative procedures of craniopharyngiomas estimated by autopsy findings. Neurol Med Chir (Tokyo) 20:341–354
Landolt A (1972) Die ultrastruktur des kraniopharyngeoms. Schweiz Arch Neurol Neurochir Psychiatry 111:313–329
Langer F (1892) Über cystiche tumoren im bereiche des infundibulum cerebri. Zeitschr f Heilkunde 13:57–68
Laufer I, Anand VK, Schwartz TH (2007) Endoscopic, endonasal extended transsphenoidal, transplanum transtuberculum approach for resection of suprasellar lesions. J Neurosurg 106:400–406
Lee Y-Y, Wong T-T, Fang Y-T, Chang K-P, Chen Y-W, Niu D-M (2008) Comparison of hypothalamopituitary axis of dysfunction of intrasellar and third ventricular craniopharyngiomas in children. Brain & Development 30:189–194
Lena G, Paredes AP, Scavarda D, Giusiano B (2005) Craniopharyngioma in children: Marseille experience. Childs Nerv Syst 21:778–784
Liszczak T, Richardson EP, Phillips JP, Jacobson S, Kornblith PL (1978) Morphological, biochemical, ultrastructural, tissue culture and clinical observations of typical and aggressive craniopharyngiomas. Acta Neuropathol (Berl) 43:191–203
Long DM, Chou SN (1973) Transcallosal removal of craniopharyngiomas within the third ventricle. J Neurosurg 39:563–567
Lopes CAS, Mair WGP (1974) Ultrastructure of the outer cortex and the pia mater in man. Acta Neuropathol (Berl) 28:79–86
Luse SA, Kernohan JW (1955) Squamous-cell nests of the pituitary gland. Cancer 8:623–628
Malamud N (1967) Psychiatric disorder with intracranial tumors of limbic system. Arch Neurol 17:113–123
Meuric S, Brauner R, Trivin C, Souberbielle J-C, Zerah M, Sainte-Rose C (2005) Influence of tumor location on the presentation and evolution of craniopharyngiomas. J Neurosurg 103(5 Suppl Pediatr):421–426
Morgan PJ, Williams LM (1996) The pars tuberalis of the pituitary: a Gateway for neuroendocrine output. Rev Reprod 1:153–161
Mortini P, Losa M, Pozzobon G, Barzaghi R, Riva M, Acerno S, Angius D, Weber G, Chiumello G, Giovanelli M (2011) Neurosurgical treatment of craniopharyngioma in adults and children: early and long-term results in a large case series. J Neurosurg 114:1350–1359
Mott FW, Barratt JOW (1899) Three cases of tumor of the third ventricle. Arch Neurol Psychiatry 1:417–439
Newmark L (1917) A case of infundibular tumor in a child. Arch Int Med 19:550–563
Northfield DWC (1957) Rathke-pouch tumours. Brain 80:293–312
Northfield DWC (1973) The surgery of the central nervous system: a textbook for postgraduate students. Blackwell, London, pp 280–330
O’Rahilly R, Müller F (1986) The meninges in human development. J Neuropathol Exp Neurol 45:588–608
O’Rahilly RR, Miller F (2001) Human embryology and teratology. Wiley-Liss, New York
Orthner H, Rettinger E (1965) An intraventricular craniopharyngioma, with a contribution to a hypothalamically induced Korsakoff syndrome. Comparative review of the hypothalamically inducible disorders of the memory and instinctual life in humans and animals Fortschr Neurol Psychiatr Grenzgeb 33:299–331
Pan J, Qi S, Lu Y, Fan J, Zhang X, Zhou J, Pen J (2011) Intraventricular craniopharyngioma: morphological analysis and outcome evaluation of 17 cases. Acta Neurochir (Wien) 153:773–784
Pang D (2005) Craniopharyngiomas. In: Rengachary SS, Ellenbogen RG (eds) Principles of neurosurgery, 2nd edn. Elsevier Mosby, Edinburgh, pp 621–646
Pascual JM, González-Llanos F, Barrios L, Roda JM (2004) Intraventricular craniopharyngiomas: topographical classification and surgical approach selection based on an extensive overview. Acta Neurochir (Wien) 146:785–802
Pascual JM, Carrasco R, Prieto R, Gonzalez-Llanos F, Alvarez F, Roda JM (2008) Craniopharyngioma classification. J Neurosurg 109:1180–1183, Letter
Pascual JM, Prieto R, Navas M, Carrasco R (2010) Conquest of third ventricle craniopharyngiomas. J Neurosurg 112:1156–1161, Letter
Pertuiset B, Janny P, Allègre G, Olivier L (1962) Cranio-pharyngiomes simulant une tumeur antérieure du III ventricule. Presse Med 70:1846–1848
Pertuiset B (1975) Craniopharyngiomas. In: Vinken PJ, Bruin GW (eds) Handbook of clinical neurology, vol 19. Part II: Tumors of the brain and skull. North Holland, Amsterdam, pp 531–572
Petito CK, DeGirolami U, Earle KM (1976) Craniopharyngiomas: a clinical and pathological review. Cancer 37:1944–1952
Pierre-Kahn A, Brauner R, Renier D, Saint-Rose C, Gangemi MA, Rappaport R, Hirsch JF (1988) Traitement des craniopharyngiomes de l’enfant. Arch Fr Pediatr 45:163–167
Poretti A, Grotzer MA, Ribi K, Schonle E, Boltshauser E (2004) Outcome of craniopharyngioma in children: long term complications and quality of life. Dev Med Child Neurol 46:220–229
Puget S, Garnett M, Wray A, Grill J, Habrand JL, Bodaert N, Zerah M, Bezerra M, Renier D, Pierre-Kahn A, Sainte-Rose C (2007) Pediatric craniopharyngiomas: classification and treatment according to the degree of hypothalamic involvement. J Neurosurg 106(1 Suppl):3–12
Qi S, Lu Y, Pan J, Zhang X, Long H, Fan J (2011) Anatomic relations of the arachnoidea around the pituitary stalk: relevance for surgical removal of craniopharyngiomas Acta Neurochir (Wien) 153:785–96
Raybaud C, Rabehanta P, Girard N (1991) Aspects radiologiques des craniopharyngiomas. Neurochirurgie 37(Suppl 1):44–58
Reeves AG, Plum F (1969) Hyperphagia, rage and dementia accompanying a ventromedial hypothalamic neoplasm. Arch Neurol 20:616–624
Rossi A, Cama A, Consales A, Gandolfo C, Garrè ML, Milanaccio C, Pavanello M, Piatelli G, Ravegnani M, Tortori Donati P (2006) Neuroimaging of pediatric craniopharyngiomas: a pictorial essay. J Pediatr Endocrinol Metab 19(Suppl 1):299–319
Rougerie J, Fardeau M (1962) Les Cranio-pharyngiomes. Masson, Paris
Rougerie J (1979) What can be expected from surgical treatment of cranioparyngiomas in children? Childs Brain 5:433–449
Roussy G, Mossinger M (1934) Les méninges périhypophysaires; leurs rapports avec l’hypophyse. Rev Neurol 1:568–570
Rouvière H, Giroud A, Desclaux P, Roux P (1947) Le développement du lobe antérieur de l’hypophyse et ses consequences physio-pathologiques. Ann Anat Path 17:113–124
Rushing EJ, Giangaspero F, Paulus W, Burger PC (2007) Craniopharyngioma. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) WHO classification of tumors of the central nervous system, 4th edn. International Agency for Research of Cancer, Lyon, pp 238–240
Saeki N, Murai H, Kubota M, Fujimoto N, Iuchi T, Yamaura A, Sunami K (2002) Heavily T2 weighted MR images of anterior optic pathways in patients with sellar and parasellar tumours-prediction of surgical anatomy. Acta Neurochir 144: 25–35
Saint Rose C, Puget S, Wray A, Zerah M, Grill J, Brauner R, Boddaert N, Pierre-Khan A (2005) Craniopharyngioma: the pendulum of surgical management. Childs Nerv Syst 21:691–695
Samii M, Tatagiba M (1995) Craniopharyngioma. In: Kaye AH, Laws ER Jr (eds) Brain tumors. An encyclopedic approach. Churchill Livingstone, New York
Sartoretti-Schefer S, Wichmann W, Aguzzi A, Valavanis A (1997) MR Differentiation of adamantinomatous and squamous-papillary craniopharyngiomas. AJNR 18:77–87
Schäfer EA (1922) Discussion on disease of the pituitary body. The structure and functions of the pituitary. In: Biedl A Physiologie und Pathologie der hypophyse. von JF Bergmann, München Wiesbaden, pp 1–20
Schilder P, Weissmann M (1927) Amente psychose bei hypophysengangtumor. Ztschr Neurol Psychiatr 110:767–778
Schmidt B, Gherardi R, Poirier J, Caron JP (1984) Craniopharyngiome pediculè du troisième ventricule. Rev Neurol 140:281–283
Shi XE, Wu B, Zhou ZG, Fan T, Zhang YL (2006) Microsurgical treatment of craniopharyngiomas: report of 284 patients. Chin Med J 119:1653–1663
Shillito J (1980) Craniopharyngiomas: the subfrontal approach or none at all? Clin Neurosurg 27:188–205
Simonds JP (1922) The pathological anatomy and histology of the hypophysis. In: Barker LF (ed): Endocrinology and metabolism, vol 1. D. Appleton, New York, p 799
Solov’ev GS, Bogdanov AV, Panteleev SM, Yanin VL (2008) Embryonic morphogenesis of the human pituitary. Neurosci Behav Physiol 38:829–833
Steiner L, Payne BR, Prasad D, Lindquist C, Steiner M (2000) Gamma surgery in cerebral vascular lesions, malformations, tumors, and functional disorders of the nervous system. In: Schmidek HH, Sweet WH (eds) Operative neurosurgical techniques, indications, methods and results, 4th edn. WB Saunders, Philadelphia, pp 670–706
Steno J (1985) Microsurgical topography of craniopharyngiomas. Acta Neurochir (Suppl) 35:94–100
Steno J, Malácek M, Bízik I (2004) Tumor-third ventricular relationships in supradiaphragmatic craniopharyngiomas: correlation on morphological, magnetic resonance imaging, and operative findings. Neurosurgery 54:1051–1060
Strada F (1911) Beitrage zur Kenntniss der Gerschwulste der hypophyse und der hypophysengegend. Virchows Arch f Path Anat 203:1–65
Sumi T, Stefeneanu L, Kovacs K (1993) Squamous-cell nests in the pars tuberalis of the human pituitary: immunocytochemical and in situ hybridization studies. Endocrine Pathol 4:155–161
Sunderland S (1945) The meningeal relations of the human hypophysis cerebri. J Anat 79:33–37
Svolos DG (1969) Craniopharyngiomas. A study based on 108 verified cases. Acta Chir Scand Suppl 403:8–44
Sweet WH (1976) Radical surgical treatment of craniopharyngioma. Clin Neurosurg 23:52–79
Sweet WH (1988) Craniopharyngiomas, with a note on Rathke’s cleft or epithelial cyst and on suprasellar cysts. In: Schmideck HH, Sweet WH (eds) Operative neurosurgical techniques, indications, methods and results, 2nd edn. Grune and Stratton, New York, pp 349–379
Szeifert GT, Pasztor E (1993) Could craniopharyngiomas produce pituitary hormones? Neurol Res 15:68–69
Tachibana O, Yamashima T, Yamashita J, Takabatake Y (1994) Immunohistochemical expression of human chorionic gonadotropin and P-glycoprotein in human pituitary glands and craniopharyngiomas. J Neurosurg 80:79–84
Thapar K, Kovacs K (1998) Neoplasms of the sellar region. In: Bigner DD, McLendon RE, Bruner JM (eds): Russell and Rubenstein’s Pathology of tumors of the nervous system, 6th edn, vol 2. Edward Arnold, London, pp 561–680
Tomita T, Bowman RM (2005) Craniopharyngiomas in children: surgical experience at children’s memorial hospital. Childs Nerv Syst 21:729–746
Van Den Bergh R, Brucher JM (1970) (1970) L’abord transventriculaire dans les craniopharyngiomes du troisième ventricule. Aspects neuro-chirurgicaux et neuropathologiques Neurochirurgie 16:51–65
Van Effenterre R, Boch AL (2002) Craniopharyngioma in adults and children: a study of 122 surgical cases. J Neurosurg 97:3–11
Von Mihalkovics V (1875) Wirbelsaite und Hirnanhang. Arch f Mikr Anat 11:389–441
Wang K-C, Kim S-K, Choe G, Chi JG, Cho B-K (2002) Growth patterns of craniopharyngioma in children: role of the diaphragm sellae and its surgical implication. Surg Neurol 57:25–33
Weiner HL, Wisoff JH, Rosenberg ME, Kupersmith MJ, Cohen H, Zagzag D, Shiminski-Maher T, Flamm ES, Epstein FJ, Miller DC (1994) Craniopharyngiomas: a clinicopathological analysis of factors predictive of recurrence and functional outcome. Neurosurgery 35:1001–1011
Wheatley T, Clark JDA, Stewart S (1986) Craniopharyngioma with hyperprolactinaemia due to a prolactinoma. J Neurol Neurosurg Psychiatr 49:1305–1307
Williams M, Pennybacker J (1954) Memory disturbances in third ventricle tumours. J Neurol Neurosurg Psychiat 17:115–123
Wislocki GB (1936) The meningeal relations of the hypophysis cerebri. I The relations in adult mammals Anat Rec 67:273–293
Wislocki GB (1937) The meningeal relationships of the hypophysis cerebri. II An embryological study of the meninges and blood vessels of the human hypophysis Am J Anat 61:95–125
Yamada H, Haratake J, Narasaki T, Oda T (1995) Embryonal craniopharyngioma. Case report of the morphogenesis of a craniopharyngioma Cancer 75:2971–2977
Yasargil MG (1996) Craniopharyngioma. In: Yasargil MG (ed) Microneurosurgery, vol IV-B: microneurosurgery of CNS tumors. Georg Thieme, Stuttgart New York, pp 205–223
Zada G, Lin N, Ojerholm E, Ramkissoon S, Laws ER (2010) Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships. Neurosurg Focus 28:E4
Zhang YQ, Wang CC, Ma ZY (2002) Pediatric craniopharyngiomas: clinicomorphological study of 189 cases. Pediatr Neurosurg 36:80–84
Zhang YQ, Ma ZY, Wu ZB, Luo SQ, Wang ZC (2008) Radical resection of 202 pediatric craniopharyngiomas with special reference to the surgical approaches and hypothalamic protection. Pediatr Neurosurg 44:435–443
Zhou L, You C (2009) Craniopharyngioma classification. J Neurosurg 111:197–199, Letter
Ziegler E (1902) Lehrbuch der Speziellen Pathologische Anatomie. Von Gustav Fischer, Jena, p 403
Zuccaro G (2005) Radical resection of craniopharyngioma. Childs Nerv Syst 21:679–690
Zülch KJ (1975) Atlas of gross neurosurgical pathology. Springer, New York, pp 155–160
Zülch KJ (1986) Brain tumors. Their biology and pathology, 3rd edn. Springer, Berlin, pp 426–432
Acknowledgements
We especially thank Crystal Smith, Reference Librarian of the History of Medicine Department of the National Library of Medicine (NLM) at the National Intitutes of Health, Bethesda, MD, USA for her kind guidance and assistance at the National Library of Medicine during our process of search and review of the articles and monographs used in this study. We are also indebted to Lucretia MacLure and all the staff at The Francis Countway Medical Library at Harvard Medical School, Boston, MA, USA for their invaluable help in obtaining a considerable amount of the original research material used for this study. Finally, we want to thank George Hamilton for his critical review of language and style of the manuscript.
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This substantial piece of work makes a compelling case for a new classification of craniopharyngiomas. Whereas the “Not strictly intraventricular” name does not quite slip off the tongue, the concept will give those working in the field, particularly those adept in the extended endoscopic transsphenoidal procedure, some help in deciding on the radicality of their resection. Also to add a word of caution, as things stand, radiation techniques do continue to have a very major place in the management of these tumours. There is little mention of the role of this therapy here.
Michael Powell
London, UK
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Pascual, J.M., Prieto, R. & Carrasco, R. Infundibulo-tuberal or not strictly intraventricular craniopharyngioma: evidence for a major topographical category. Acta Neurochir 153, 2403–2426 (2011). https://doi.org/10.1007/s00701-011-1149-4
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DOI: https://doi.org/10.1007/s00701-011-1149-4