RT Journal Article SR Electronic T1 Thrombectomy Using the EmboTrap Clot-Retrieving Device for the Treatment of Acute Ischemic Stroke: A Glimpse of Clinical Evidence JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology DO 10.3174/ajnr.A7708 A1 X. Bai A1 Z. Fu A1 Z. Sun A1 R. Xu A1 X. Guo A1 Q. Tian A1 A.A. Dmytriw A1 H. Zhao A1 W. Wang A1 X. Wang A1 A.B. Patel A1 B. Yang A1 L. Jiao YR 2022 UL http://www.ajnr.org/content/early/2022/12/01/ajnr.A7708.abstract AB BACKGROUND: The EmboTrap Recanalization Device is a novel stent retriever for thrombectomy in the setting of acute ischemic stroke due to large-vessel occlusion.PURPOSE: Our aim was to summarize the safety and efficacy of the EmboTrap Recanalization Device in acute ischemic stroke–large-vessel occlusion through a systematic review and meta-analysis.DATA SOURCES: Medline, EMBASE, the Cochrane Library, Web of Science, and Google Scholar were searched up to April 2022.STUDY SELECTION: Nine observational studies using the EmboTrap Recanalization Device were selected.DATA ANALYSIS: We adapted effect size with 95% CIs for dichotomous data. P value <.05 was statistically significant.DATA SYNTHESIS: The estimated rate of successful recanalization (modified TICI 2b–3) was 90% (95% CI, 86%–95%; I2 = 82.4%); 90-day favorable outcome (mRS 0–2), 53% (95% CI, 42%–63%; I2 = 88.6%); modified first-pass effect, 43% (95% CI, 35%–51%; I2 = 63.7%); and first-pass effect, 36% (95% CI, 29%–46%; I2 = 10.7%). The rate of any intracerebral hemorrhage was 19% (95% CI, 16%–22%; I2 = 0.0%); symptomatic intracerebral hemorrhage, 5% (95% CI, 1%–8%; I2 = 84.6%); and 90-day mortality, 14% (95% CI, 9%–19%; I2 = 79.3%). Subgroup analysis showed higher rates of complete recanalization for EmboTrap II than for the EmboTrap System.LIMITATIONS: The included studies are single-arm without direct comparison with other stent retrievers. Some of the studies recruited had a small sample size and were limited by the retrospective study design. In addition, the uncertain heterogeneity among studies was high.CONCLUSIONS: The EmboTrap Recanalization Device is safe and efficient in treating acute ischemic stroke due to large-vessel occlusion.AISacute ischemic strokeFPEfirst-pass effectICHintracerebral hemorrhageLVOlarge-vessel occlusionmFPEmodified first-pass effectMTmechanical thrombectomymTICImodified TICIsICHsymptomatic intracerebral hemorrhage